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Example 6 with LocalParameter

use of cbit.vcell.mapping.ParameterContext.LocalParameter in project vcell by virtualcell.

the class Xmlproducer method getXML.

private Element getXML(RbmKineticLaw param) {
    Element kinetics = new Element(XMLTags.KineticsTag);
    switch(param.getRateLawType()) {
        case MassAction:
            {
                kinetics.setAttribute(XMLTags.KineticsTypeAttrTag, XMLTags.RbmKineticTypeMassAction);
                break;
            }
        case MichaelisMenten:
            {
                kinetics.setAttribute(XMLTags.KineticsTypeAttrTag, XMLTags.RbmKineticTypeMichaelisMenten);
                break;
            }
        case Saturable:
            {
                kinetics.setAttribute(XMLTags.KineticsTypeAttrTag, XMLTags.RbmKineticTypeSaturable);
                break;
            }
    }
    HashMap<ParameterRoleEnum, String> roleHash = new HashMap<ParameterRoleEnum, String>();
    roleHash.put(RbmKineticLawParameterType.MassActionForwardRate, XMLTags.RbmMassActionKfRole);
    roleHash.put(RbmKineticLawParameterType.MassActionReverseRate, XMLTags.RbmMassActionKrRole);
    roleHash.put(RbmKineticLawParameterType.MichaelisMentenKcat, XMLTags.RbmMichaelisMentenKcatRole);
    roleHash.put(RbmKineticLawParameterType.MichaelisMentenKm, XMLTags.RbmMichaelisMentenKmRole);
    roleHash.put(RbmKineticLawParameterType.SaturableVmax, XMLTags.RbmSaturableVmaxRole);
    roleHash.put(RbmKineticLawParameterType.SaturableKs, XMLTags.RbmSaturableKsRole);
    roleHash.put(RbmKineticLawParameterType.RuleRate, XMLTags.RbmRuleRateRole);
    roleHash.put(RbmKineticLawParameterType.UserDefined, XMLTags.RbmUserDefinedRole);
    // Add Kinetics Parameters
    LocalParameter[] parameters = param.getLocalParameters();
    for (int i = 0; i < parameters.length; i++) {
        LocalParameter parm = parameters[i];
        Element tempparameter = new Element(XMLTags.ParameterTag);
        // Get parameter attributes
        tempparameter.setAttribute(XMLTags.NameAttrTag, mangle(parm.getName()));
        tempparameter.setAttribute(XMLTags.ParamRoleAttrTag, roleHash.get(parm.getRole()));
        VCUnitDefinition unit = parm.getUnitDefinition();
        if (unit != null) {
            tempparameter.setAttribute(XMLTags.VCUnitDefinitionAttrTag, unit.getSymbol());
        }
        Expression expression = parm.getExpression();
        if (expression != null) {
            tempparameter.addContent(mangleExpression(expression));
        }
        // Add the parameter to the general kinetics object
        kinetics.addContent(tempparameter);
    }
    return kinetics;
}
Also used : LocalParameter(cbit.vcell.mapping.ParameterContext.LocalParameter) VCUnitDefinition(cbit.vcell.units.VCUnitDefinition) HashMap(java.util.HashMap) Expression(cbit.vcell.parser.Expression) Element(org.jdom.Element) ParameterRoleEnum(cbit.vcell.mapping.ParameterContext.ParameterRoleEnum)

Example 7 with LocalParameter

use of cbit.vcell.mapping.ParameterContext.LocalParameter in project vcell by virtualcell.

the class BioModelParametersTableModel method propertyChange.

@Override
public void propertyChange(java.beans.PropertyChangeEvent evt) {
    super.propertyChange(evt);
    if (evt.getSource() instanceof EditableSymbolTableEntry) {
        int changeRow = getRowIndex((EditableSymbolTableEntry) evt.getSource());
        if (changeRow >= 0) {
            fireTableRowsUpdated(changeRow, changeRow);
        }
    } else {
        String propertyName = evt.getPropertyName();
        if (evt.getSource() == bioModel.getModel()) {
            if (propertyName.equals(Model.PROPERTY_NAME_MODEL_PARAMETERS)) {
                ModelParameter[] oldValue = (ModelParameter[]) evt.getOldValue();
                if (oldValue != null) {
                    for (EditableSymbolTableEntry parameter : oldValue) {
                        parameter.removePropertyChangeListener(this);
                    }
                }
                ModelParameter[] newValue = (ModelParameter[]) evt.getNewValue();
                if (newValue != null) {
                    for (EditableSymbolTableEntry parameter : newValue) {
                        parameter.addPropertyChangeListener(this);
                    }
                }
                refreshData();
            } else if (propertyName.equals(Model.PROPERTY_NAME_SPECIES_CONTEXTS)) {
                SpeciesContext[] oldValue = (SpeciesContext[]) evt.getOldValue();
                if (oldValue != null) {
                    for (SpeciesContext sc : oldValue) {
                        sc.removePropertyChangeListener(this);
                    }
                }
                SpeciesContext[] newValue = (SpeciesContext[]) evt.getNewValue();
                if (newValue != null) {
                    for (SpeciesContext sc : newValue) {
                        sc.addPropertyChangeListener(this);
                    }
                }
                refreshData();
            } else if (propertyName.equals(Model.PROPERTY_NAME_REACTION_STEPS)) {
                ReactionStep[] oldValue = (ReactionStep[]) evt.getOldValue();
                if (oldValue != null) {
                    for (ReactionStep reactionStep : oldValue) {
                        reactionStep.removePropertyChangeListener(this);
                        reactionStep.getKinetics().removePropertyChangeListener(this);
                        for (KineticsParameter kineticsEditableSymbolTableEntry : reactionStep.getKinetics().getKineticsParameters()) {
                            kineticsEditableSymbolTableEntry.removePropertyChangeListener(this);
                        }
                        for (ProxyParameter proxyEditableSymbolTableEntry : reactionStep.getKinetics().getProxyParameters()) {
                            proxyEditableSymbolTableEntry.removePropertyChangeListener(this);
                        }
                        for (UnresolvedParameter unresolvedEditableSymbolTableEntry : reactionStep.getKinetics().getUnresolvedParameters()) {
                            unresolvedEditableSymbolTableEntry.removePropertyChangeListener(this);
                        }
                    }
                }
                ReactionStep[] newValue = (ReactionStep[]) evt.getNewValue();
                if (newValue != null) {
                    for (ReactionStep reactionStep : newValue) {
                        reactionStep.addPropertyChangeListener(this);
                        reactionStep.getKinetics().addPropertyChangeListener(this);
                        for (KineticsParameter kineticsEditableSymbolTableEntry : reactionStep.getKinetics().getKineticsParameters()) {
                            kineticsEditableSymbolTableEntry.addPropertyChangeListener(this);
                        }
                        for (ProxyParameter proxyEditableSymbolTableEntry : reactionStep.getKinetics().getProxyParameters()) {
                            proxyEditableSymbolTableEntry.addPropertyChangeListener(this);
                        }
                        for (UnresolvedParameter unresolvedEditableSymbolTableEntry : reactionStep.getKinetics().getUnresolvedParameters()) {
                            unresolvedEditableSymbolTableEntry.addPropertyChangeListener(this);
                        }
                    }
                }
                refreshData();
            } else if (evt.getPropertyName().equals(RbmModelContainer.PROPERTY_NAME_REACTION_RULE_LIST)) {
                List<ReactionRule> oldValue = (List<ReactionRule>) evt.getOldValue();
                if (oldValue != null) {
                    for (ReactionRule rs : oldValue) {
                        rs.removePropertyChangeListener(this);
                    }
                }
                List<ReactionRule> newValue = (List<ReactionRule>) evt.getNewValue();
                if (newValue != null) {
                    for (ReactionRule rs : newValue) {
                        rs.addPropertyChangeListener(this);
                    }
                }
                refreshData();
            }
        } else if (evt.getSource() == bioModel) {
            if (propertyName.equals(BioModel.PROPERTY_NAME_SIMULATION_CONTEXTS)) {
                SimulationContext[] oldValue = (SimulationContext[]) evt.getOldValue();
                for (SimulationContext simulationContext : oldValue) {
                    simulationContext.removePropertyChangeListener(this);
                    simulationContext.getGeometryContext().removePropertyChangeListener(this);
                    for (StructureMapping mapping : simulationContext.getGeometryContext().getStructureMappings()) {
                        mapping.removePropertyChangeListener(this);
                        for (EditableSymbolTableEntry parameter : mapping.getParameters()) {
                            parameter.removePropertyChangeListener(this);
                        }
                    }
                    simulationContext.getReactionContext().removePropertyChangeListener(this);
                    for (SpeciesContextSpec spec : simulationContext.getReactionContext().getSpeciesContextSpecs()) {
                        spec.removePropertyChangeListener(this);
                        for (EditableSymbolTableEntry parameter : spec.getParameters()) {
                            parameter.removePropertyChangeListener(this);
                        }
                    }
                    for (ElectricalStimulus elect : simulationContext.getElectricalStimuli()) {
                        elect.removePropertyChangeListener(this);
                        for (EditableSymbolTableEntry parameter : elect.getParameters()) {
                            parameter.removePropertyChangeListener(this);
                        }
                    }
                    for (SpatialObject spatialObject : simulationContext.getSpatialObjects()) {
                        spatialObject.removePropertyChangeListener(this);
                    }
                    for (SpatialProcess spatialProcess : simulationContext.getSpatialProcesses()) {
                        spatialProcess.removePropertyChangeListener(this);
                        for (LocalParameter p : spatialProcess.getParameters()) {
                            p.removePropertyChangeListener(this);
                        }
                    }
                    for (SimulationContextParameter p : simulationContext.getSimulationContextParameters()) {
                        p.removePropertyChangeListener(this);
                    }
                }
                SimulationContext[] newValue = (SimulationContext[]) evt.getNewValue();
                for (SimulationContext simulationContext : newValue) {
                    simulationContext.addPropertyChangeListener(this);
                    simulationContext.getGeometryContext().addPropertyChangeListener(this);
                    for (StructureMapping mapping : simulationContext.getGeometryContext().getStructureMappings()) {
                        mapping.addPropertyChangeListener(this);
                        for (EditableSymbolTableEntry parameter : mapping.getParameters()) {
                            parameter.addPropertyChangeListener(this);
                        }
                    }
                    simulationContext.getReactionContext().addPropertyChangeListener(this);
                    for (SpeciesContextSpec spec : simulationContext.getReactionContext().getSpeciesContextSpecs()) {
                        spec.addPropertyChangeListener(this);
                        for (EditableSymbolTableEntry parameter : spec.getParameters()) {
                            parameter.addPropertyChangeListener(this);
                        }
                    }
                    for (ElectricalStimulus elect : simulationContext.getElectricalStimuli()) {
                        elect.addPropertyChangeListener(this);
                        for (EditableSymbolTableEntry parameter : elect.getParameters()) {
                            parameter.addPropertyChangeListener(this);
                        }
                    }
                    for (SpatialObject spatialObject : simulationContext.getSpatialObjects()) {
                        spatialObject.addPropertyChangeListener(this);
                    }
                    for (SpatialProcess spatialProcess : simulationContext.getSpatialProcesses()) {
                        spatialProcess.addPropertyChangeListener(this);
                        for (LocalParameter p : spatialProcess.getParameters()) {
                            p.addPropertyChangeListener(this);
                        }
                    }
                    for (SimulationContextParameter p : simulationContext.getSimulationContextParameters()) {
                        p.addPropertyChangeListener(this);
                    }
                }
                refreshData();
            }
        } else if (evt.getSource() instanceof GeometryContext && evt.getPropertyName().equals(GeometryContext.PROPERTY_STRUCTURE_MAPPINGS)) {
            StructureMapping[] oldValue = (StructureMapping[]) evt.getOldValue();
            if (oldValue != null) {
                for (StructureMapping mapping : oldValue) {
                    mapping.removePropertyChangeListener(this);
                    for (EditableSymbolTableEntry parameter : mapping.getParameters()) {
                        parameter.removePropertyChangeListener(this);
                    }
                }
            }
            StructureMapping[] newValue = (StructureMapping[]) evt.getNewValue();
            if (newValue != null) {
                for (StructureMapping mapping : newValue) {
                    mapping.addPropertyChangeListener(this);
                    for (EditableSymbolTableEntry parameter : mapping.getParameters()) {
                        parameter.addPropertyChangeListener(this);
                    }
                }
            }
            refreshData();
        } else if (evt.getSource() instanceof ReactionStep && (evt.getPropertyName().equals(ReactionStep.PROPERTY_NAME_KINETICS))) {
            Kinetics oldValue = (Kinetics) evt.getOldValue();
            if (oldValue != null) {
                oldValue.removePropertyChangeListener(this);
                for (KineticsParameter kineticsEditableSymbolTableEntry : oldValue.getKineticsParameters()) {
                    kineticsEditableSymbolTableEntry.removePropertyChangeListener(this);
                }
                for (ProxyParameter proxyEditableSymbolTableEntry : oldValue.getProxyParameters()) {
                    proxyEditableSymbolTableEntry.removePropertyChangeListener(this);
                }
                for (UnresolvedParameter unresolvedEditableSymbolTableEntry : oldValue.getUnresolvedParameters()) {
                    unresolvedEditableSymbolTableEntry.removePropertyChangeListener(this);
                }
            }
            Kinetics newValue = (Kinetics) evt.getNewValue();
            if (newValue != null) {
                newValue.addPropertyChangeListener(this);
                for (KineticsParameter kineticsEditableSymbolTableEntry : newValue.getKineticsParameters()) {
                    kineticsEditableSymbolTableEntry.addPropertyChangeListener(this);
                }
                for (ProxyParameter proxyEditableSymbolTableEntry : newValue.getProxyParameters()) {
                    proxyEditableSymbolTableEntry.addPropertyChangeListener(this);
                }
                for (UnresolvedParameter unresolvedEditableSymbolTableEntry : newValue.getUnresolvedParameters()) {
                    unresolvedEditableSymbolTableEntry.addPropertyChangeListener(this);
                }
            }
            refreshData();
        } else if (evt.getSource() instanceof SimulationContext && evt.getPropertyName().equals(SimulationContext.PROPERTY_NAME_SPATIALPROCESSES)) {
            SpatialProcess[] oldValue = (SpatialProcess[]) evt.getOldValue();
            if (oldValue != null) {
                for (SpatialProcess process : oldValue) {
                    process.removePropertyChangeListener(this);
                    for (EditableSymbolTableEntry parameter : process.getParameters()) {
                        parameter.removePropertyChangeListener(this);
                    }
                }
            }
            SpatialProcess[] newValue = (SpatialProcess[]) evt.getNewValue();
            if (newValue != null) {
                for (SpatialProcess process : newValue) {
                    process.addPropertyChangeListener(this);
                    for (EditableSymbolTableEntry parameter : process.getParameters()) {
                        parameter.addPropertyChangeListener(this);
                    }
                }
            }
            refreshData();
        } else if (evt.getSource() instanceof SimulationContext && evt.getPropertyName().equals(SimulationContext.PROPERTY_NAME_SPATIALOBJECTS)) {
            SpatialObject[] oldValue = (SpatialObject[]) evt.getOldValue();
            if (oldValue != null) {
                for (SpatialObject spatialObject : oldValue) {
                    spatialObject.removePropertyChangeListener(this);
                }
            }
            SpatialObject[] newValue = (SpatialObject[]) evt.getNewValue();
            if (newValue != null) {
                for (SpatialObject spatialObject : newValue) {
                    spatialObject.addPropertyChangeListener(this);
                }
            }
            refreshData();
        } else if (evt.getSource() instanceof SpatialObject && evt.getPropertyName().equals(SpatialObject.PROPERTY_NAME_QUANTITYCATEGORIESENABLED)) {
            refreshData();
        } else if (evt.getSource() instanceof SimulationContext && evt.getPropertyName().equals(SimulationContext.PROPERTY_NAME_SIMULATIONCONTEXTPARAMETERS)) {
            SimulationContextParameter[] oldValue = (SimulationContextParameter[]) evt.getOldValue();
            if (oldValue != null) {
                for (SimulationContextParameter param : oldValue) {
                    param.removePropertyChangeListener(this);
                }
            }
            SimulationContextParameter[] newValue = (SimulationContextParameter[]) evt.getNewValue();
            if (newValue != null) {
                for (SimulationContextParameter param : newValue) {
                    param.addPropertyChangeListener(this);
                }
            }
            refreshData();
        } else if (evt.getSource() instanceof Kinetics && (evt.getPropertyName().equals(Kinetics.PROPERTY_NAME_KINETICS_PARAMETERS))) {
            EditableSymbolTableEntry[] oldValue = (EditableSymbolTableEntry[]) evt.getOldValue();
            if (oldValue != null) {
                for (int i = 0; i < oldValue.length; i++) {
                    oldValue[i].removePropertyChangeListener(this);
                }
            }
            EditableSymbolTableEntry[] newValue = (EditableSymbolTableEntry[]) evt.getNewValue();
            if (newValue != null) {
                for (int i = 0; i < newValue.length; i++) {
                    newValue[i].addPropertyChangeListener(this);
                }
            }
            refreshData();
        // } else if(evt.getSource() instanceof ReactionRuleEmbedded) {
        // ReactionRuleEmbedded reactionRule = (ReactionRuleEmbedded) evt.getSource();
        // int changeRow = getRowIndex(reactionRule);
        // if (changeRow >= 0) {
        // fireTableRowsUpdated(changeRow, changeRow);
        // }
        }
    }
}
Also used : UnresolvedParameter(cbit.vcell.model.Kinetics.UnresolvedParameter) SpeciesContext(cbit.vcell.model.SpeciesContext) SpeciesContextSpec(cbit.vcell.mapping.SpeciesContextSpec) StructureMapping(cbit.vcell.mapping.StructureMapping) SpatialObject(cbit.vcell.mapping.spatial.SpatialObject) KineticsParameter(cbit.vcell.model.Kinetics.KineticsParameter) SpatialProcess(cbit.vcell.mapping.spatial.processes.SpatialProcess) ArrayList(java.util.ArrayList) List(java.util.List) GeometryContext(cbit.vcell.mapping.GeometryContext) ReactionRule(cbit.vcell.model.ReactionRule) SimulationContext(cbit.vcell.mapping.SimulationContext) SimulationContextParameter(cbit.vcell.mapping.SimulationContext.SimulationContextParameter) LocalParameter(cbit.vcell.mapping.ParameterContext.LocalParameter) ModelParameter(cbit.vcell.model.Model.ModelParameter) ElectricalStimulus(cbit.vcell.mapping.ElectricalStimulus) ProxyParameter(cbit.vcell.model.ProxyParameter) ReactionStep(cbit.vcell.model.ReactionStep) Kinetics(cbit.vcell.model.Kinetics) EditableSymbolTableEntry(cbit.vcell.model.EditableSymbolTableEntry)

Example 8 with LocalParameter

use of cbit.vcell.mapping.ParameterContext.LocalParameter in project vcell by virtualcell.

the class MathMapping_4_8 method getMathSymbol0.

/**
 * Substitutes appropriate variables for speciesContext bindings
 *
 * @return cbit.vcell.parser.Expression
 * @param origExp cbit.vcell.parser.Expression
 * @param structureMapping cbit.vcell.mapping.StructureMapping
 */
private String getMathSymbol0(SymbolTableEntry ste, StructureMapping structureMapping) throws MappingException {
    String steName = ste.getName();
    if (ste instanceof Kinetics.KineticsParameter) {
        Integer count = localNameCountHash.get(steName);
        if (count == null) {
            throw new MappingException("KineticsParameter " + steName + " not found in local name count");
        }
        if (count > 1 || steName.equals("J")) {
            return steName + "_" + ste.getNameScope().getName();
        // return getNameScope().getSymbolName(ste);
        } else {
            return steName;
        }
    }
    if (ste instanceof MathMapping_4_8.ProbabilityParameter) {
        // be careful here, to see if we need mangle the reaction name
        MathMapping_4_8.ProbabilityParameter probParm = (MathMapping_4_8.ProbabilityParameter) ste;
        return probParm.getName();
    }
    if (ste instanceof MathMapping_4_8.SpeciesConcentrationParameter) {
        MathMapping_4_8.SpeciesConcentrationParameter concParm = (MathMapping_4_8.SpeciesConcentrationParameter) ste;
        return concParm.getSpeciesContextSpec().getSpeciesContext().getName() + MATH_FUNC_SUFFIX_SPECIES_CONCENTRATION;
    }
    if (ste instanceof MathMapping_4_8.SpeciesCountParameter) {
        MathMapping_4_8.SpeciesCountParameter countParm = (MathMapping_4_8.SpeciesCountParameter) ste;
        return countParm.getSpeciesContextSpec().getSpeciesContext().getName() + MATH_VAR_SUFFIX_SPECIES_COUNT;
    }
    if (ste instanceof MathMapping_4_8.EventAssignmentInitParameter) {
        MathMapping_4_8.EventAssignmentInitParameter eventInitParm = (MathMapping_4_8.EventAssignmentInitParameter) ste;
        return eventInitParm.getName() + MATH_FUNC_SUFFIX_EVENTASSIGN_INIT;
    }
    if (ste instanceof Model.ReservedSymbol) {
        return steName;
    }
    if (ste instanceof Membrane.MembraneVoltage) {
        return steName;
    }
    if (ste instanceof Structure.StructureSize) {
        Structure structure = ((Structure.StructureSize) ste).getStructure();
        StructureMapping.StructureMappingParameter sizeParameter = simContext.getGeometryContext().getStructureMapping(structure).getSizeParameter();
        return getMathSymbol(sizeParameter, structureMapping);
    }
    if (ste instanceof ProxyParameter) {
        ProxyParameter pp = (ProxyParameter) ste;
        return getMathSymbol0(pp.getTarget(), structureMapping);
    }
    // 
    Model model = simContext.getModel();
    if (ste instanceof ModelParameter) {
        ModelParameter mp = (ModelParameter) ste;
        if (simContext.getGeometry().getDimension() == 0) {
            return mp.getName();
        } else {
            if (mp.getExpression().getSymbols() == null) {
                return mp.getName();
            }
            // check if global param variant name exists in globalVarsHash. If so, return it, else, throw exception.
            Hashtable<String, Expression> smVariantsHash = globalParamVariantsHash.get(mp);
            String variantName = mp.getName() + "_" + TokenMangler.fixTokenStrict(structureMapping.getStructure().getName());
            if (smVariantsHash.get(variantName) != null) {
                return variantName;
            } else {
                // global param variant doesn't exist in the hash, so get the substituted expression for global param and
                // gather all symbols (speciesContexts) that do not match with arg 'structureMapping' to display a proper error message.
                Expression expr = null;
                try {
                    expr = substituteGlobalParameters(mp.getExpression());
                } catch (ExpressionException e) {
                    e.printStackTrace(System.out);
                    throw new RuntimeException("Could not substitute expression for global parameter '" + mp.getName() + "' with expression '" + "'" + e.getMessage());
                }
                // find symbols (typically speciesContexts) in 'exp' that do not match with the arg 'structureMapping'
                String[] symbols = expr.getSymbols();
                String msg = "";
                if (symbols != null) {
                    Vector<String> spContextNamesVector = new Vector<String>();
                    for (int j = 0; j < symbols.length; j++) {
                        SpeciesContext sc = model.getSpeciesContext(symbols[j]);
                        if (sc != null) {
                            if (!sc.getStructure().compareEqual(structureMapping.getStructure())) {
                                spContextNamesVector.addElement(sc.getName());
                            }
                        }
                    }
                    for (int i = 0; (spContextNamesVector != null && i < spContextNamesVector.size()); i++) {
                        if (i == 0) {
                            msg += "'" + spContextNamesVector.elementAt(i) + ", ";
                        } else if (i == spContextNamesVector.size() - 1) {
                            msg += spContextNamesVector.elementAt(i) + "'";
                        } else {
                            msg += spContextNamesVector.elementAt(i) + ", ";
                        }
                    }
                }
                throw new RuntimeException("Global parameter '" + mp.getName() + "' is not defined in compartment '" + structureMapping.getStructure().getName() + "', but was referenced in that compartment." + "\n\nExpression '" + mp.getExpression().infix() + "' for global parameter '" + mp.getName() + "' expands to '" + expr.infix() + "' " + "and contains species " + msg + " that is/are not in adjacent compartments.");
            }
        // return (mp.getName()+"_"+TokenMangler.fixTokenStrict(structureMapping.getStructure().getName()));
        }
    }
    if (ste instanceof SpeciesContextSpec.SpeciesContextSpecParameter) {
        SpeciesContextSpec.SpeciesContextSpecParameter scsParm = (SpeciesContextSpec.SpeciesContextSpecParameter) ste;
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_InitialConcentration) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + MATH_FUNC_SUFFIX_SPECIES_INIT_CONCENTRATION;
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_InitialCount) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + MATH_FUNC_SUFFIX_SPECIES_INIT_COUNT;
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_DiffusionRate) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_diffusionRate";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_BoundaryValueXm) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_boundaryXm";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_BoundaryValueXp) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_boundaryXp";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_BoundaryValueYm) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_boundaryYm";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_BoundaryValueYp) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_boundaryYp";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_BoundaryValueZm) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_boundaryZm";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_BoundaryValueZp) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_boundaryZp";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_VelocityX) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_velocityX";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_VelocityY) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_velocityY";
        }
        if (scsParm.getRole() == SpeciesContextSpec.ROLE_VelocityZ) {
            return ((SpeciesContextSpec) (scsParm.getNameScope().getScopedSymbolTable())).getSpeciesContext().getName() + "_velocityZ";
        }
    }
    if (ste instanceof ElectricalDevice.ElectricalDeviceParameter) {
        ElectricalDevice.ElectricalDeviceParameter edParm = (ElectricalDevice.ElectricalDeviceParameter) ste;
        ElectricalDevice electricalDevice = (ElectricalDevice) edParm.getNameScope().getScopedSymbolTable();
        if (electricalDevice instanceof MembraneElectricalDevice) {
            String nameWithScope = ((MembraneElectricalDevice) electricalDevice).getMembraneMapping().getMembrane().getNameScope().getName();
            if (edParm.getRole() == ElectricalDevice.ROLE_TotalCurrent) {
                return "I_" + nameWithScope;
            }
            if (edParm.getRole() == ElectricalDevice.ROLE_TransmembraneCurrent) {
                return "F_" + nameWithScope;
            }
        // }else if (electricalDevice instanceof CurrentClampElectricalDevice) {
        // if (edParm.getRole()==ElectricalDevice.ROLE_TotalCurrentDensity){
        // return "I_"+((CurrentClampElectricalDevice)electricalDevice).getCurrentClampStimulus().getNameScope().getName();
        // }
        // if (edParm.getRole()==ElectricalDevice.ROLE_TransmembraneCurrentDensity){
        // return "F_"+((CurrentClampElectricalDevice)electricalDevice).getCurrentClampStimulus().getNameScope().getName();
        // }
        // }else if (electricalDevice instanceof VoltageClampElectricalDevice) {
        // if (edParm.getRole()==ElectricalDevice.ROLE_TotalCurrentDensity){
        // return "I_"+((VoltageClampElectricalDevice)electricalDevice).getVoltageClampStimulus().getNameScope().getName();
        // }
        // if (edParm.getRole()==ElectricalDevice.ROLE_TransmembraneCurrentDensity){
        // return "F_"+((VoltageClampElectricalDevice)electricalDevice).getVoltageClampStimulus().getNameScope().getName();
        // }
        }
    }
    if (ste instanceof LocalParameter && ((LocalParameter) ste).getNameScope() instanceof ElectricalStimulus.ElectricalStimulusNameScope) {
        LocalParameter esParm = (LocalParameter) ste;
        String nameWithScope = esParm.getNameScope().getName();
        if (esParm.getRole() == ElectricalStimulusParameterType.TotalCurrent) {
            return "I_" + nameWithScope;
        } else if (esParm.getRole() == ElectricalStimulusParameterType.Voltage) {
            return "V_" + nameWithScope;
        }
    }
    StructureTopology structTopology = model.getStructureTopology();
    if (ste instanceof StructureMapping.StructureMappingParameter) {
        StructureMapping.StructureMappingParameter smParm = (StructureMapping.StructureMappingParameter) ste;
        Structure structure = ((StructureMapping) (smParm.getNameScope().getScopedSymbolTable())).getStructure();
        int role = smParm.getRole();
        if (role == StructureMapping.ROLE_VolumeFraction) {
            return "VolFract_" + (structTopology.getInsideFeature((Membrane) structure)).getNameScope().getName();
        } else {
            String nameWithScope = structure.getNameScope().getName();
            if (role == StructureMapping.ROLE_SurfaceToVolumeRatio) {
                return "SurfToVol_" + nameWithScope;
            } else if (role == StructureMapping.ROLE_InitialVoltage) {
                return smParm.getName();
            } else if (role == StructureMapping.ROLE_SpecificCapacitance) {
                return "C_" + nameWithScope;
            } else if (role == StructureMapping.ROLE_AreaPerUnitArea) {
                return "AreaPerUnitArea_" + nameWithScope;
            } else if (role == StructureMapping.ROLE_AreaPerUnitVolume) {
                return "AreaPerUnitVolume_" + nameWithScope;
            } else if (role == StructureMapping.ROLE_VolumePerUnitArea) {
                return "VolumePerUnitArea_" + nameWithScope;
            } else if (role == StructureMapping.ROLE_VolumePerUnitVolume) {
                return "VolumePerUnitVolume_" + nameWithScope;
            } else if (role == StructureMapping.ROLE_Size) {
                if (simContext.getGeometry().getDimension() == 0) {
                    // if geometry is compartmental, make sure compartment sizes are set if referenced in model.
                    if (smParm.getExpression() == null || smParm.getExpression().isZero()) {
                        throw new MappingException("\nIn non-spatial application '" + getSimulationContext().getName() + "', " + "size of structure '" + structure.getName() + "' must be assigned a " + "positive value if referenced in the model.\n\nPlease go to 'Structure Mapping' tab to check the size.");
                    }
                }
                return "Size_" + nameWithScope;
            }
        }
    }
    // 
    if (ste instanceof SpeciesContext) {
        SpeciesContext sc = (SpeciesContext) ste;
        SpeciesContextMapping scm = getSpeciesContextMapping(sc);
        // 
        if (structureMapping instanceof FeatureMapping) {
            // 
            if (scm.getVariable() != null && !scm.getVariable().getName().equals(steName)) {
                return scm.getVariable().getName();
            }
        // 
        // for reactions within a spatially resolved membrane, may need "_INSIDE" or "_OUTSIDE" for jump condition
        // 
        // if the membrane is distributed, then always use the plain variable.
        // 
        } else if (structureMapping instanceof MembraneMapping) {
            Membrane membrane = ((MembraneMapping) structureMapping).getMembrane();
            // 
            if (sc.getStructure() instanceof Membrane || getResolved(structureMapping) == false) {
                if (scm.getVariable() != null && !(scm.getVariable().getName().equals(steName))) {
                    return scm.getVariable().getName();
                }
            // 
            // if the speciesContext is outside the membrane
            // 
            } else {
                SpeciesContextSpec scs = simContext.getReactionContext().getSpeciesContextSpec(sc);
                if (sc.getStructure() == structTopology.getInsideFeature(membrane) || sc.getStructure() == structTopology.getOutsideFeature(membrane)) {
                    if (getResolved(structureMapping) && !scs.isConstant()) {
                        if (!scs.isDiffusing()) {
                            throw new MappingException("Enable diffusion in Application '" + simContext.getName() + "'. This must be done for any species (e.g '" + sc.getName() + "') in flux reactions.\n\n" + "To save or run simulations, set the diffusion rate to a non-zero " + "value in Initial Conditions or disable those reactions in Specifications->Reactions.");
                        }
                        return scm.getVariable().getName() + (sc.getStructure() == structTopology.getInsideFeature(membrane) ? "_INSIDE" : "_OUTSIDE");
                    } else {
                        return scm.getSpeciesContext().getName();
                    }
                } else {
                    throw new MappingException(sc.getName() + " shouldn't be involved with structure " + structureMapping.getStructure().getName());
                }
            }
        }
    }
    return getNameScope().getSymbolName(ste);
}
Also used : MembraneMapping(cbit.vcell.mapping.MembraneMapping) SpeciesContextMapping(cbit.vcell.mapping.SpeciesContextMapping) SpeciesContext(cbit.vcell.model.SpeciesContext) StructureMappingParameter(cbit.vcell.mapping.StructureMapping.StructureMappingParameter) SpeciesContextSpec(cbit.vcell.mapping.SpeciesContextSpec) StructureMapping(cbit.vcell.mapping.StructureMapping) ExpressionException(cbit.vcell.parser.ExpressionException) MappingException(cbit.vcell.mapping.MappingException) KineticsParameter(cbit.vcell.model.Kinetics.KineticsParameter) FeatureMapping(cbit.vcell.mapping.FeatureMapping) Membrane(cbit.vcell.model.Membrane) Structure(cbit.vcell.model.Structure) Vector(java.util.Vector) SpeciesContextSpecParameter(cbit.vcell.mapping.SpeciesContextSpec.SpeciesContextSpecParameter) SpeciesContextSpecParameter(cbit.vcell.mapping.SpeciesContextSpec.SpeciesContextSpecParameter) StructureTopology(cbit.vcell.model.Model.StructureTopology) LocalParameter(cbit.vcell.mapping.ParameterContext.LocalParameter) ModelParameter(cbit.vcell.model.Model.ModelParameter) ElectricalStimulus(cbit.vcell.mapping.ElectricalStimulus) ProxyParameter(cbit.vcell.model.ProxyParameter) SpeciesContextSpecProxyParameter(cbit.vcell.mapping.SpeciesContextSpec.SpeciesContextSpecProxyParameter) StructureMappingParameter(cbit.vcell.mapping.StructureMapping.StructureMappingParameter) Expression(cbit.vcell.parser.Expression) Model(cbit.vcell.model.Model)

Example 9 with LocalParameter

use of cbit.vcell.mapping.ParameterContext.LocalParameter in project vcell by virtualcell.

the class BioEvent method setTriggerType.

public void setTriggerType(TriggerType triggerType) {
    if (triggerType == this.triggerType) {
        return;
    }
    this.triggerType = triggerType;
    ModelUnitSystem modelUnitSystem = getSimulationContext().getModel().getUnitSystem();
    VCUnitDefinition unit_TBD = modelUnitSystem.getInstance_TBD();
    VCUnitDefinition unit_Dimensionless = modelUnitSystem.getInstance_DIMENSIONLESS();
    VCUnitDefinition unit_modelTime = modelUnitSystem.getTimeUnit();
    LocalParameter delayParam = parameterContext.new LocalParameter(BioEventParameterType.TriggerDelay.getDefaultName(), new Expression(0.0), BioEventParameterType.TriggerDelay, unit_modelTime, BioEventParameterType.TriggerDelay.getDescription());
    LocalParameter generatedGeneralTriggerParam = parameterContext.new LocalParameter(BioEventParameterType.GeneralTriggerFunction.getDefaultName(), null, BioEventParameterType.GeneralTriggerFunction, unit_Dimensionless, BioEventParameterType.GeneralTriggerFunction.getDescription());
    switch(triggerType) {
        case GeneralTrigger:
            {
                try {
                    parameterContext.setLocalParameters(new LocalParameter[] { delayParam, parameterContext.new LocalParameter(BioEventParameterType.GeneralTriggerFunction.getDefaultName(), new Expression(0.0), BioEventParameterType.GeneralTriggerFunction, unit_Dimensionless, BioEventParameterType.GeneralTriggerFunction.getDescription()) });
                } catch (PropertyVetoException | ExpressionBindingException e) {
                    e.printStackTrace();
                    throw new RuntimeException(e.getMessage(), e);
                }
                break;
            }
        case ObservableAboveThreshold:
        case ObservableBelowThreshold:
            {
                try {
                    parameterContext.setLocalParameters(new LocalParameter[] { delayParam, generatedGeneralTriggerParam, parameterContext.new LocalParameter(BioEventParameterType.Observable.getDefaultName(), null, BioEventParameterType.Observable, unit_TBD, BioEventParameterType.Observable.getDescription()), parameterContext.new LocalParameter(BioEventParameterType.Threshold.getDefaultName(), new Expression(1.0), BioEventParameterType.Threshold, unit_TBD, BioEventParameterType.Threshold.getDescription()) });
                } catch (PropertyVetoException | ExpressionBindingException e) {
                    e.printStackTrace();
                    throw new RuntimeException(e.getMessage(), e);
                }
                break;
            }
        case SingleTriggerTime:
            {
                try {
                    parameterContext.setLocalParameters(new LocalParameter[] { delayParam, generatedGeneralTriggerParam, parameterContext.new LocalParameter(BioEventParameterType.SingleTriggerTime.getDefaultName(), new Expression(1.0), BioEventParameterType.SingleTriggerTime, unit_modelTime, BioEventParameterType.SingleTriggerTime.getDescription()) });
                } catch (PropertyVetoException | ExpressionBindingException e) {
                    e.printStackTrace();
                    throw new RuntimeException(e.getMessage(), e);
                }
                break;
            }
        case LinearRangeTimes:
        case LogRangeTimes:
            {
                try {
                    parameterContext.setLocalParameters(new LocalParameter[] { delayParam, generatedGeneralTriggerParam, parameterContext.new LocalParameter(BioEventParameterType.RangeMinTime.getDefaultName(), new Expression(1.0), BioEventParameterType.RangeMinTime, unit_modelTime, BioEventParameterType.RangeMinTime.getDescription()), parameterContext.new LocalParameter(BioEventParameterType.RangeMaxTime.getDefaultName(), new Expression(10.0), BioEventParameterType.RangeMaxTime, unit_modelTime, BioEventParameterType.RangeMaxTime.getDescription()), parameterContext.new LocalParameter(BioEventParameterType.RangeNumTimes.getDefaultName(), new Expression(9), BioEventParameterType.RangeNumTimes, unit_modelTime, BioEventParameterType.RangeNumTimes.getDescription()) });
                } catch (PropertyVetoException | ExpressionBindingException e) {
                    e.printStackTrace();
                    throw new RuntimeException(e.getMessage(), e);
                }
                break;
            }
        case ListOfTimes:
            {
                try {
                    parameterContext.setLocalParameters(new LocalParameter[] { delayParam, generatedGeneralTriggerParam, parameterContext.new LocalParameter(BioEventParameterType.TimeListItem.getDefaultName() + "0", new Expression(1.0), BioEventParameterType.TimeListItem, unit_modelTime, BioEventParameterType.TimeListItem.getDescription()), parameterContext.new LocalParameter(BioEventParameterType.TimeListItem.getDefaultName() + "1", new Expression(2.0), BioEventParameterType.TimeListItem, unit_modelTime, BioEventParameterType.TimeListItem.getDescription()), parameterContext.new LocalParameter(BioEventParameterType.TimeListItem.getDefaultName() + "2", new Expression(3.0), BioEventParameterType.TimeListItem, unit_modelTime, BioEventParameterType.TimeListItem.getDescription()) });
                } catch (PropertyVetoException | ExpressionBindingException e) {
                    e.printStackTrace();
                    throw new RuntimeException(e.getMessage(), e);
                }
                break;
            }
        default:
            {
                throw new RuntimeException("unsupported rule-based kinetic law " + triggerType);
            }
    }
}
Also used : LocalParameter(cbit.vcell.mapping.ParameterContext.LocalParameter) VCUnitDefinition(cbit.vcell.units.VCUnitDefinition) Expression(cbit.vcell.parser.Expression) ModelUnitSystem(cbit.vcell.model.ModelUnitSystem)

Example 10 with LocalParameter

use of cbit.vcell.mapping.ParameterContext.LocalParameter in project vcell by virtualcell.

the class BioEvent method gatherIssues.

public void gatherIssues(IssueContext issueContext, List<Issue> issueList) {
    // check all event assignment symbols
    if (eventAssignmentList != null) {
        for (EventAssignment ea : eventAssignmentList) {
            // the target of the event assignment
            SymbolTableEntry ste = simulationContext.getEntry(ea.getTarget().getName());
            // SymbolTableEntry ste = parameterContext.getEntry(ea.getTarget().getName());
            if (ste == null) {
                String msg = "Missing Parameter '" + ea.getTarget().getName() + "' used in BioEvent '" + name + "'.";
                String tip = "Remove the Action containing the missing parameter from the BioEvent '" + name + "'.";
                issueList.add(new Issue(this, issueContext, IssueCategory.Identifiers, msg, tip, Issue.Severity.ERROR));
                // found one issue on this event assignment, we show it and go to next
                break;
            }
            // the expression of the event assignment
            Expression exp = ea.assignmentExpression;
            String[] symbols = exp.getSymbols();
            if (symbols != null) {
                boolean found = false;
                for (String symbol : symbols) {
                    ste = simulationContext.getEntry(symbol);
                    if (ste == null) {
                        String msg = "Missing Symbol '" + symbol + "' in Assignment Expression for BioEvent '" + name + "'.";
                        String tip = "Remove the Action containing the missing Symbol from the Assignment Expression of the BioEvent '" + name + "'.";
                        issueList.add(new Issue(this, issueContext, IssueCategory.Identifiers, msg, tip, Issue.Severity.ERROR));
                        found = true;
                        break;
                    }
                }
                if (found == true) {
                    // found one issue on this event assignment, we show it and go to next
                    break;
                }
            }
        }
    } else {
        String msg = "No Action assigned to BioEvent '" + name + "'.";
        String tip = "Please assign an Action to the BioEvent '" + name + "'.";
        issueList.add(new Issue(this, issueContext, IssueCategory.Identifiers, msg, tip, Issue.Severity.WARNING));
    }
    // check all trigger condition symbols
    for (LocalParameter lp : getEventParameters()) {
        if (lp.getExpression() != null && lp.getExpression().getSymbols() != null) {
            String[] symbols = lp.getExpression().getSymbols();
            boolean found = false;
            for (String symbol : symbols) {
                SymbolTableEntry ste = simulationContext.getEntry(symbol);
                if (ste == null) {
                    String msg = "Missing Symbol '" + symbol + "' in the Trigger Condition for BioEvent '" + name + "'.";
                    String tip = "Remove the Action containing the missing Symbol from the Trigger Condition of the BioEvent '" + name + "'.";
                    issueList.add(new Issue(this, issueContext, IssueCategory.Identifiers, msg, tip, Issue.Severity.ERROR));
                    found = true;
                    break;
                }
            }
            if (found == true) {
                // found one issue with a parameter on this trigger condition, we show it and stop
                break;
            }
        }
    }
}
Also used : LocalParameter(cbit.vcell.mapping.ParameterContext.LocalParameter) SymbolTableEntry(cbit.vcell.parser.SymbolTableEntry) Issue(org.vcell.util.Issue) EventAssignment(cbit.vcell.mapping.BioEvent.EventAssignment) Expression(cbit.vcell.parser.Expression)

Aggregations

LocalParameter (cbit.vcell.mapping.ParameterContext.LocalParameter)45 Expression (cbit.vcell.parser.Expression)31 VCUnitDefinition (cbit.vcell.units.VCUnitDefinition)17 PropertyVetoException (java.beans.PropertyVetoException)12 ModelParameter (cbit.vcell.model.Model.ModelParameter)11 SpeciesContext (cbit.vcell.model.SpeciesContext)11 ExpressionException (cbit.vcell.parser.ExpressionException)11 ModelUnitSystem (cbit.vcell.model.ModelUnitSystem)9 Parameter (cbit.vcell.model.Parameter)9 ArrayList (java.util.ArrayList)9 SymbolTableEntry (cbit.vcell.parser.SymbolTableEntry)8 Element (org.jdom.Element)8 ProxyParameter (cbit.vcell.model.ProxyParameter)7 CurrentDensityClampStimulus (cbit.vcell.mapping.CurrentDensityClampStimulus)6 LocalProxyParameter (cbit.vcell.mapping.ParameterContext.LocalProxyParameter)6 TotalCurrentClampStimulus (cbit.vcell.mapping.TotalCurrentClampStimulus)6 Model (cbit.vcell.model.Model)6 ElectricalStimulus (cbit.vcell.mapping.ElectricalStimulus)5 CompartmentSubDomain (cbit.vcell.math.CompartmentSubDomain)5 Domain (cbit.vcell.math.Variable.Domain)5