use of dr.inference.mcmc.MCMC in project beast-mcmc by beast-dev.
the class LognormalPriorTest method testLognormalPrior.
public void testLognormalPrior() {
// ConstantPopulation constant = new ConstantPopulation(Units.Type.YEARS);
// constant.setN0(popSize); // popSize
Parameter popSize = new Parameter.Default(6.0);
popSize.setId(ConstantPopulationModelParser.POPULATION_SIZE);
ConstantPopulationModel demo = new ConstantPopulationModel(popSize, Units.Type.YEARS);
//Likelihood
Likelihood dummyLikelihood = new DummyLikelihood(demo);
// Operators
OperatorSchedule schedule = new SimpleOperatorSchedule();
MCMCOperator operator = new ScaleOperator(popSize, 0.75);
operator.setWeight(1.0);
schedule.addOperator(operator);
// Log
ArrayLogFormatter formatter = new ArrayLogFormatter(false);
MCLogger[] loggers = new MCLogger[2];
loggers[0] = new MCLogger(formatter, 1000, false);
// loggers[0].add(treeLikelihood);
loggers[0].add(popSize);
loggers[1] = new MCLogger(new TabDelimitedFormatter(System.out), 100000, false);
// loggers[1].add(treeLikelihood);
loggers[1].add(popSize);
// MCMC
MCMC mcmc = new MCMC("mcmc1");
MCMCOptions options = new MCMCOptions(1000000);
// meanInRealSpace="false"
DistributionLikelihood logNormalLikelihood = new DistributionLikelihood(new LogNormalDistribution(1.0, 1.0), 0);
logNormalLikelihood.addData(popSize);
List<Likelihood> likelihoods = new ArrayList<Likelihood>();
likelihoods.add(logNormalLikelihood);
Likelihood prior = new CompoundLikelihood(0, likelihoods);
likelihoods.clear();
likelihoods.add(dummyLikelihood);
Likelihood likelihood = new CompoundLikelihood(-1, likelihoods);
likelihoods.clear();
likelihoods.add(prior);
likelihoods.add(likelihood);
Likelihood posterior = new CompoundLikelihood(0, likelihoods);
mcmc.setShowOperatorAnalysis(true);
mcmc.init(options, posterior, schedule, loggers);
mcmc.run();
// time
System.out.println(mcmc.getTimer().toString());
// Tracer
List<Trace> traces = formatter.getTraces();
ArrayTraceList traceList = new ArrayTraceList("LognormalPriorTest", traces, 0);
for (int i = 1; i < traces.size(); i++) {
traceList.analyseTrace(i);
}
// <expectation name="param" value="4.48168907"/>
TraceCorrelation popSizeStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(ConstantPopulationModelParser.POPULATION_SIZE));
System.out.println("Expectation of Log-Normal(1,1) is e^(M+S^2/2) = e^(1.5) = " + Math.exp(1.5));
assertExpectation(ConstantPopulationModelParser.POPULATION_SIZE, popSizeStats, Math.exp(1.5));
}
use of dr.inference.mcmc.MCMC in project beast-mcmc by beast-dev.
the class GeneralSubstitutionModelTest method testGeneralSubstitutionModel.
public void testGeneralSubstitutionModel() {
// Sub model
FrequencyModel freqModel = new FrequencyModel(dataType, alignment.getStateFrequencies());
// dimension="5" value="1.0"
Parameter ratesPara = new Parameter.Default(GeneralSubstitutionModelParser.RATES, 5, 1.0);
// relativeTo="5"
GeneralSubstitutionModel generalSubstitutionModel = new GeneralSubstitutionModel(dataType, freqModel, ratesPara, 4);
//siteModel
GammaSiteModel siteModel = new GammaSiteModel(generalSubstitutionModel);
Parameter mu = new Parameter.Default(GammaSiteModelParser.MUTATION_RATE, 1.0, 0, Double.POSITIVE_INFINITY);
siteModel.setMutationRateParameter(mu);
//treeLikelihood
SitePatterns patterns = new SitePatterns(alignment, null, 0, -1, 1, true);
TreeLikelihood treeLikelihood = new TreeLikelihood(patterns, treeModel, siteModel, null, null, false, false, true, false, false);
treeLikelihood.setId(TreeLikelihoodParser.TREE_LIKELIHOOD);
// Operators
OperatorSchedule schedule = new SimpleOperatorSchedule();
MCMCOperator operator = new ScaleOperator(ratesPara, 0.5);
operator.setWeight(1.0);
schedule.addOperator(operator);
Parameter rootHeight = treeModel.getRootHeightParameter();
rootHeight.setId(TREE_HEIGHT);
operator = new ScaleOperator(rootHeight, 0.5);
operator.setWeight(1.0);
schedule.addOperator(operator);
Parameter internalHeights = treeModel.createNodeHeightsParameter(false, true, false);
operator = new UniformOperator(internalHeights, 10.0);
schedule.addOperator(operator);
operator = new SubtreeSlideOperator(treeModel, 1, 1, true, false, false, false, CoercionMode.COERCION_ON);
schedule.addOperator(operator);
operator = new ExchangeOperator(ExchangeOperator.NARROW, treeModel, 1.0);
// operator.doOperation();
schedule.addOperator(operator);
operator = new ExchangeOperator(ExchangeOperator.WIDE, treeModel, 1.0);
// operator.doOperation();
schedule.addOperator(operator);
operator = new WilsonBalding(treeModel, 1.0);
// operator.doOperation();
schedule.addOperator(operator);
// Log
ArrayLogFormatter formatter = new ArrayLogFormatter(false);
MCLogger[] loggers = new MCLogger[2];
loggers[0] = new MCLogger(formatter, 1000, false);
loggers[0].add(treeLikelihood);
loggers[0].add(rootHeight);
loggers[0].add(ratesPara);
loggers[1] = new MCLogger(new TabDelimitedFormatter(System.out), 100000, false);
loggers[1].add(treeLikelihood);
loggers[1].add(rootHeight);
loggers[1].add(ratesPara);
// MCMC
MCMC mcmc = new MCMC("mcmc1");
MCMCOptions options = new MCMCOptions(10000000);
mcmc.setShowOperatorAnalysis(true);
mcmc.init(options, treeLikelihood, schedule, loggers);
mcmc.run();
// time
System.out.println(mcmc.getTimer().toString());
// Tracer
List<Trace> traces = formatter.getTraces();
ArrayTraceList traceList = new ArrayTraceList("GeneralSubstitutionModelTest", traces, 0);
for (int i = 1; i < traces.size(); i++) {
traceList.analyseTrace(i);
}
// <expectation name="likelihood" value="-1815.75"/>
// <expectation name="treeModel.rootHeight" value="6.42048E-2"/>
// <expectation name="rateAC" value="6.08986E-2"/>
TraceCorrelation likelihoodStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(TreeLikelihoodParser.TREE_LIKELIHOOD));
assertExpectation(TreeLikelihoodParser.TREE_LIKELIHOOD, likelihoodStats, -1815.75);
TraceCorrelation treeHeightStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(TREE_HEIGHT));
assertExpectation(TREE_HEIGHT, treeHeightStats, 0.0640787258170083);
TraceCorrelation rateACStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(GeneralSubstitutionModelParser.RATES + "1"));
assertExpectation(GeneralSubstitutionModelParser.RATES + "1", rateACStats, 0.061071756742081366);
}
use of dr.inference.mcmc.MCMC in project beast-mcmc by beast-dev.
the class ARGAddRemoveOperatorTest method flatPriorTester.
private void flatPriorTester(ARGModel arg, int chainLength, int sampleTreeEvery, double nodeCountSetting, double rootHeightAlpha, double rootHeightBeta, int maxCount) throws IOException, Importer.ImportException {
MCMC mcmc = new MCMC("mcmc1");
MCMCOptions options = new MCMCOptions(chainLength);
// double nodeCountSetting = 2.0;
// double rootHeightAlpha = 100;
// double rootHeightBeta = 0.5;
OperatorSchedule schedule = getSchedule(arg);
ARGUniformPrior uniformPrior = new ARGUniformPrior(arg, maxCount, arg.getExternalNodeCount());
PoissonDistribution poisson = new PoissonDistribution(nodeCountSetting);
DistributionLikelihood nodeCountPrior = new DistributionLikelihood(poisson, 0.0);
ARGReassortmentNodeCountStatistic nodeCountStatistic = new ARGReassortmentNodeCountStatistic("nodeCount", arg);
nodeCountPrior.addData(nodeCountStatistic);
DistributionLikelihood rootPrior = new DistributionLikelihood(new GammaDistribution(rootHeightAlpha, rootHeightBeta), 0.0);
CompoundParameter rootHeight = (CompoundParameter) arg.createNodeHeightsParameter(true, false, false);
rootPrior.addData(rootHeight);
List<Likelihood> likelihoods = new ArrayList<Likelihood>();
likelihoods.add(uniformPrior);
likelihoods.add(rootPrior);
likelihoods.add(nodeCountPrior);
CompoundLikelihood compoundLikelihood = new CompoundLikelihood(1, likelihoods);
compoundLikelihood.setId("likelihood1");
MCLogger[] loggers = new MCLogger[3];
loggers[0] = new MCLogger(new TabDelimitedFormatter(System.out), 10000, false);
loggers[0].add(compoundLikelihood);
loggers[0].add(arg);
File file = new File("test.args");
file.deleteOnExit();
FileOutputStream out = new FileOutputStream(file);
loggers[1] = new ARGLogger(arg, new TabDelimitedFormatter(out), sampleTreeEvery, "test");
ArrayLogFormatter formatter = new ArrayLogFormatter(false);
loggers[2] = new MCLogger(formatter, sampleTreeEvery, false);
loggers[2].add(arg);
arg.getRootHeightParameter().setId("root");
loggers[2].add(arg.getRootHeightParameter());
mcmc.setShowOperatorAnalysis(true);
mcmc.init(options, compoundLikelihood, schedule, loggers);
mcmc.run();
out.flush();
out.close();
List<Trace> traces = formatter.getTraces();
// Set<String> uniqueTrees = new HashSet<String>();
//
// NexusImporter importer = new NexusImporter(new FileReader(file));
// while (importer.hasTree()) {
// Tree t = importer.importNextTree();
// uniqueTrees.add(Tree.Utils.uniqueNewick(t, t.getRoot()));
// }
//
// TestCase.assertEquals(numTopologies, uniqueTrees.size()); List<Trace> traces = formatter.getTraces();
ArrayTraceList traceList = new ArrayTraceList("ARGTest", traces, 0);
for (int i = 1; i < traces.size(); i++) {
traceList.analyseTrace(i);
}
TraceCorrelation nodeCountStats = traceList.getCorrelationStatistics(1);
TraceCorrelation rootHeightStats = traceList.getCorrelationStatistics(4);
assertExpectation("nodeCount", nodeCountStats, poisson.truncatedMean(maxCount));
assertExpectation(TreeModelParser.ROOT_HEIGHT, rootHeightStats, rootHeightAlpha * rootHeightBeta);
}
use of dr.inference.mcmc.MCMC in project beast-mcmc by beast-dev.
the class RandomLocalClockTestProblem method testRandomLocalClock.
public void testRandomLocalClock() throws Exception {
Parameter popSize = new Parameter.Default(ConstantPopulationModelParser.POPULATION_SIZE, 0.077, 0, Double.POSITIVE_INFINITY);
ConstantPopulationModel constantModel = createRandomInitialTree(popSize);
CoalescentLikelihood coalescent = new CoalescentLikelihood(treeModel, null, new ArrayList<TaxonList>(), constantModel);
coalescent.setId("coalescent");
// clock model
Parameter ratesParameter = new Parameter.Default(RandomLocalClockModelParser.RATES, 10, 1);
Parameter rateIndicatorParameter = new Parameter.Default(RandomLocalClockModelParser.RATE_INDICATORS, 10, 1);
Parameter meanRateParameter = new Parameter.Default(RandomLocalClockModelParser.CLOCK_RATE, 1, 1.0);
RandomLocalClockModel branchRateModel = new RandomLocalClockModel(treeModel, meanRateParameter, rateIndicatorParameter, ratesParameter, false, 0.5);
SumStatistic rateChanges = new SumStatistic("rateChangeCount", true);
rateChanges.addStatistic(rateIndicatorParameter);
RateStatistic meanRate = new RateStatistic("meanRate", treeModel, branchRateModel, true, true, RateStatisticParser.MEAN);
RateStatistic coefficientOfVariation = new RateStatistic(RateStatisticParser.COEFFICIENT_OF_VARIATION, treeModel, branchRateModel, true, true, RateStatisticParser.COEFFICIENT_OF_VARIATION);
RateCovarianceStatistic covariance = new RateCovarianceStatistic("covariance", treeModel, branchRateModel);
// Sub model
Parameter freqs = new Parameter.Default(alignment.getStateFrequencies());
Parameter kappa = new Parameter.Default(HKYParser.KAPPA, 1.0, 0, Double.POSITIVE_INFINITY);
FrequencyModel f = new FrequencyModel(Nucleotides.INSTANCE, freqs);
HKY hky = new HKY(kappa, f);
//siteModel
GammaSiteModel siteModel = new GammaSiteModel(hky);
Parameter mu = new Parameter.Default(GammaSiteModelParser.MUTATION_RATE, 1.0, 0, Double.POSITIVE_INFINITY);
siteModel.setMutationRateParameter(mu);
//treeLikelihood
SitePatterns patterns = new SitePatterns(alignment, null, 0, -1, 1, true);
TreeLikelihood treeLikelihood = new TreeLikelihood(patterns, treeModel, siteModel, branchRateModel, null, false, false, true, false, false);
treeLikelihood.setId(TreeLikelihoodParser.TREE_LIKELIHOOD);
// Operators
OperatorSchedule schedule = new SimpleOperatorSchedule();
MCMCOperator operator = new ScaleOperator(kappa, 0.75);
operator.setWeight(1.0);
schedule.addOperator(operator);
operator = new ScaleOperator(ratesParameter, 0.75);
operator.setWeight(10.0);
schedule.addOperator(operator);
operator = new BitFlipOperator(rateIndicatorParameter, 15.0, true);
schedule.addOperator(operator);
operator = new ScaleOperator(popSize, 0.75);
operator.setWeight(3.0);
schedule.addOperator(operator);
Parameter rootHeight = treeModel.getRootHeightParameter();
rootHeight.setId(TREE_HEIGHT);
operator = new ScaleOperator(rootHeight, 0.75);
operator.setWeight(3.0);
schedule.addOperator(operator);
Parameter internalHeights = treeModel.createNodeHeightsParameter(false, true, false);
operator = new UniformOperator(internalHeights, 30.0);
schedule.addOperator(operator);
operator = new SubtreeSlideOperator(treeModel, 15.0, 0.0077, true, false, false, false, CoercionMode.COERCION_ON);
schedule.addOperator(operator);
operator = new ExchangeOperator(ExchangeOperator.NARROW, treeModel, 15.0);
// operator.doOperation();
schedule.addOperator(operator);
operator = new ExchangeOperator(ExchangeOperator.WIDE, treeModel, 3.0);
// operator.doOperation();
schedule.addOperator(operator);
operator = new WilsonBalding(treeModel, 3.0);
// operator.doOperation();
schedule.addOperator(operator);
//CompoundLikelihood
OneOnXPrior likelihood1 = new OneOnXPrior();
likelihood1.addData(popSize);
OneOnXPrior likelihood2 = new OneOnXPrior();
likelihood2.addData(kappa);
DistributionLikelihood likelihood3 = new DistributionLikelihood(new GammaDistribution(0.5, 2.0), 0.0);
likelihood3.addData(ratesParameter);
DistributionLikelihood likelihood4 = new DistributionLikelihood(new PoissonDistribution(1.0), 0.0);
likelihood4.addData(rateChanges);
List<Likelihood> likelihoods = new ArrayList<Likelihood>();
likelihoods.add(likelihood1);
likelihoods.add(likelihood2);
likelihoods.add(likelihood3);
likelihoods.add(likelihood4);
likelihoods.add(coalescent);
Likelihood prior = new CompoundLikelihood(0, likelihoods);
prior.setId(CompoundLikelihoodParser.PRIOR);
likelihoods.clear();
likelihoods.add(treeLikelihood);
Likelihood likelihood = new CompoundLikelihood(-1, likelihoods);
likelihoods.clear();
likelihoods.add(prior);
likelihoods.add(likelihood);
Likelihood posterior = new CompoundLikelihood(0, likelihoods);
posterior.setId(CompoundLikelihoodParser.POSTERIOR);
// Log
ArrayLogFormatter formatter = new ArrayLogFormatter(false);
MCLogger[] loggers = new MCLogger[2];
loggers[0] = new MCLogger(formatter, 1000, false);
loggers[0].add(posterior);
loggers[0].add(prior);
loggers[0].add(treeLikelihood);
loggers[0].add(rootHeight);
loggers[0].add(kappa);
// loggers[0].add(meanRate);
loggers[0].add(rateChanges);
loggers[0].add(coefficientOfVariation);
loggers[0].add(covariance);
loggers[0].add(popSize);
loggers[0].add(coalescent);
loggers[1] = new MCLogger(new TabDelimitedFormatter(System.out), 10000, false);
loggers[1].add(posterior);
loggers[1].add(treeLikelihood);
loggers[1].add(rootHeight);
loggers[1].add(meanRate);
loggers[1].add(rateChanges);
// MCMC
MCMC mcmc = new MCMC("mcmc1");
MCMCOptions options = new MCMCOptions(1000000);
mcmc.setShowOperatorAnalysis(true);
mcmc.init(options, posterior, schedule, loggers);
mcmc.run();
// time
System.out.println(mcmc.getTimer().toString());
// Tracer
List<Trace> traces = formatter.getTraces();
ArrayTraceList traceList = new ArrayTraceList("RandomLocalClockTest", traces, 0);
for (int i = 1; i < traces.size(); i++) {
traceList.analyseTrace(i);
}
// <expectation name="posterior" value="-1818.26"/>
// <expectation name="prior" value="-2.70143"/>
// <expectation name="likelihood" value="-1815.56"/>
// <expectation name="treeModel.rootHeight" value="6.363E-2"/>
// <expectation name="constant.popSize" value="9.67405E-2"/>
// <expectation name="hky.kappa" value="30.0394"/>
// <expectation name="coefficientOfVariation" value="7.02408E-2"/>
// covariance 0.47952
// <expectation name="rateChangeCount" value="0.40786"/>
// <expectation name="coalescent" value="7.29521"/>
TraceCorrelation likelihoodStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(CompoundLikelihoodParser.POSTERIOR));
assertExpectation(CompoundLikelihoodParser.POSTERIOR, likelihoodStats, -1818.26);
likelihoodStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(CompoundLikelihoodParser.PRIOR));
assertExpectation(CompoundLikelihoodParser.PRIOR, likelihoodStats, -2.70143);
likelihoodStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(TreeLikelihoodParser.TREE_LIKELIHOOD));
assertExpectation(TreeLikelihoodParser.TREE_LIKELIHOOD, likelihoodStats, -1815.56);
TraceCorrelation treeHeightStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(TREE_HEIGHT));
assertExpectation(TREE_HEIGHT, treeHeightStats, 6.363E-2);
TraceCorrelation kappaStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(HKYParser.KAPPA));
assertExpectation(HKYParser.KAPPA, kappaStats, 30.0394);
TraceCorrelation rateChangeStats = traceList.getCorrelationStatistics(traceList.getTraceIndex("rateChangeCount"));
assertExpectation("rateChangeCount", rateChangeStats, 0.40786);
TraceCorrelation coefficientOfVariationStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(RateStatisticParser.COEFFICIENT_OF_VARIATION));
assertExpectation(RateStatisticParser.COEFFICIENT_OF_VARIATION, coefficientOfVariationStats, 7.02408E-2);
TraceCorrelation covarianceStats = traceList.getCorrelationStatistics(traceList.getTraceIndex("covariance"));
assertExpectation("covariance", covarianceStats, 0.47952);
TraceCorrelation popStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(ConstantPopulationModelParser.POPULATION_SIZE));
assertExpectation(ConstantPopulationModelParser.POPULATION_SIZE, popStats, 9.67405E-2);
TraceCorrelation coalescentStats = traceList.getCorrelationStatistics(traceList.getTraceIndex("coalescent"));
assertExpectation("coalescent", coalescentStats, 7.29521);
}
use of dr.inference.mcmc.MCMC in project beast-mcmc by beast-dev.
the class TestCalibratedYuleModel method yuleTester.
private void yuleTester(TreeModel treeModel, OperatorSchedule schedule, Parameter brParameter, double S, int chainLength) throws IOException, TreeUtils.MissingTaxonException {
MCMC mcmc = new MCMC("mcmc1");
MCMCOptions options = new MCMCOptions(chainLength);
TreeLengthStatistic tls = new TreeLengthStatistic(TL, treeModel);
TreeHeightStatistic rootHeight = new TreeHeightStatistic(TREE_HEIGHT, treeModel);
SpeciationModel speciationModel = new BirthDeathGernhard08Model("yule", brParameter, null, null, BirthDeathGernhard08Model.TreeType.UNSCALED, Units.Type.SUBSTITUTIONS, false);
Likelihood speciationLikelihood = new SpeciationLikelihood(treeModel, speciationModel, "yule.like");
Taxa halfTaxa = new Taxa();
for (int i = 0; i < taxa.getTaxonCount() / 2; i++) {
halfTaxa.addTaxon(new Taxon("T" + Integer.toString(i)));
}
TMRCAStatistic tmrca = new TMRCAStatistic("tmrca(halfTaxa)", treeModel, halfTaxa, false, false);
DistributionLikelihood logNormalLikelihood = new DistributionLikelihood(new LogNormalDistribution(M, S), // meanInRealSpace="false"
0);
logNormalLikelihood.addData(tmrca);
MonophylyStatistic monophylyStatistic = new MonophylyStatistic("monophyly(halfTaxa)", treeModel, halfTaxa, null);
BooleanLikelihood booleanLikelihood = new BooleanLikelihood();
booleanLikelihood.addData(monophylyStatistic);
//CompoundLikelihood
List<Likelihood> likelihoods = new ArrayList<Likelihood>();
likelihoods.add(speciationLikelihood);
likelihoods.add(logNormalLikelihood);
likelihoods.add(booleanLikelihood);
Likelihood prior = new CompoundLikelihood(0, likelihoods);
prior.setId(CompoundLikelihoodParser.PRIOR);
ArrayLogFormatter logformatter = new ArrayLogFormatter(false);
MCLogger[] loggers = new MCLogger[1];
loggers[0] = new MCLogger(logformatter, (int) (options.getChainLength() / 10000), false);
loggers[0].add(speciationLikelihood);
loggers[0].add(rootHeight);
loggers[0].add(tmrca);
loggers[0].add(tls);
loggers[0].add(brParameter);
mcmc.setShowOperatorAnalysis(false);
mcmc.init(options, prior, schedule, loggers);
mcmc.run();
List<Trace> traces = logformatter.getTraces();
ArrayTraceList traceList = new ArrayTraceList("yuleModelTest", traces, 1000);
for (int i = 1; i < traces.size(); i++) {
traceList.analyseTrace(i);
}
NumberFormatter formatter = new NumberFormatter(8);
TraceCorrelation tlStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(TL));
TraceCorrelation treeHeightStats = traceList.getCorrelationStatistics(traceList.getTraceIndex("tmrca(halfTaxa)"));
// out.write("tmrcaHeight = \t");
out.write(formatter.format(treeHeightStats.getMean()));
out.write("\t");
double expectedNodeHeight = Math.pow(Math.E, (M + (Math.pow(S, 2) / 2)));
// out.write("expectation = \t");
out.write(formatter.format(expectedNodeHeight));
out.write("\t");
double error = Math.abs((treeHeightStats.getMean() - expectedNodeHeight) / expectedNodeHeight);
NumberFormat percentFormatter = NumberFormat.getNumberInstance();
percentFormatter.setMinimumFractionDigits(5);
percentFormatter.setMinimumFractionDigits(5);
// out.write("error = \t");
out.write(percentFormatter.format(error));
out.write("\t");
// out.write("tl.ess = \t");
out.write(Double.toString(tlStats.getESS()));
System.out.println("tmrcaHeight = " + formatter.format(treeHeightStats.getMean()) + "; expectation = " + formatter.format(expectedNodeHeight) + "; error = " + percentFormatter.format(error) + "; tl.ess = " + tlStats.getESS());
}
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