Examples with CompoundLikelihood dr.inference.model.CompoundLikelihood used on opensource projects

Example 11 with CompoundLikelihood

use of dr.inference.model.CompoundLikelihood in project beast-mcmc by beast-dev.

the class MCMCParser method parseXMLObject.

/**
     * @return an mcmc object based on the XML element it was passed.
     */
public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    MCMC mcmc = new MCMC(xo.getAttribute(NAME, "mcmc1"));
    long chainLength = xo.getLongIntegerAttribute(CHAIN_LENGTH);
    boolean useCoercion = xo.getAttribute(COERCION, true);
    long coercionDelay = chainLength / 100;
    if (xo.hasAttribute(PRE_BURNIN)) {
        coercionDelay = xo.getIntegerAttribute(PRE_BURNIN);
    }
    coercionDelay = xo.getAttribute(COERCION_DELAY, coercionDelay);
    double temperature = xo.getAttribute(TEMPERATURE, 1.0);
    long fullEvaluationCount = xo.getAttribute(FULL_EVALUATION, 2000);
    double evaluationTestThreshold = MarkovChain.EVALUATION_TEST_THRESHOLD;
    if (System.getProperty("mcmc.evaluation.threshold") != null) {
        evaluationTestThreshold = Double.parseDouble(System.getProperty("mcmc.evaluation.threshold"));
    }
    evaluationTestThreshold = xo.getAttribute(EVALUATION_THRESHOLD, evaluationTestThreshold);
    int minOperatorCountForFullEvaluation = xo.getAttribute(MIN_OPS_EVALUATIONS, 1);
    MCMCOptions options = new MCMCOptions(chainLength, fullEvaluationCount, minOperatorCountForFullEvaluation, evaluationTestThreshold, useCoercion, coercionDelay, temperature);
    OperatorSchedule opsched = (OperatorSchedule) xo.getChild(OperatorSchedule.class);
    Likelihood likelihood = (Likelihood) xo.getChild(Likelihood.class);
    likelihood.setUsed();
    if (Boolean.valueOf(System.getProperty("show_warnings", "false"))) {
        // check that all models, parameters and likelihoods are being used
        for (Likelihood l : Likelihood.FULL_LIKELIHOOD_SET) {
            if (!l.isUsed()) {
                java.util.logging.Logger.getLogger("dr.inference").warning("Likelihood, " + l.getId() + ", of class " + l.getClass().getName() + " is not being handled by the MCMC.");
            }
        }
        for (Model m : Model.FULL_MODEL_SET) {
            if (!m.isUsed()) {
                java.util.logging.Logger.getLogger("dr.inference").warning("Model, " + m.getId() + ", of class " + m.getClass().getName() + " is not being handled by the MCMC.");
            }
        }
        for (Parameter p : Parameter.FULL_PARAMETER_SET) {
            if (!p.isUsed()) {
                java.util.logging.Logger.getLogger("dr.inference").warning("Parameter, " + p.getId() + ", of class " + p.getClass().getName() + " is not being handled by the MCMC.");
            }
        }
    }
    ArrayList<Logger> loggers = new ArrayList<Logger>();
    for (int i = 0; i < xo.getChildCount(); i++) {
        Object child = xo.getChild(i);
        if (child instanceof Logger) {
            loggers.add((Logger) child);
        }
    }
    mcmc.setShowOperatorAnalysis(true);
    if (xo.hasAttribute(OPERATOR_ANALYSIS)) {
        mcmc.setOperatorAnalysisFile(XMLParser.getLogFile(xo, OPERATOR_ANALYSIS));
    }
    Logger[] loggerArray = new Logger[loggers.size()];
    loggers.toArray(loggerArray);
    java.util.logging.Logger.getLogger("dr.inference").info("\nCreating the MCMC chain:" + "\n  chainLength=" + options.getChainLength() + "\n  autoOptimize=" + options.useCoercion() + (options.useCoercion() ? "\n  autoOptimize delayed for " + options.getCoercionDelay() + " steps" : "") + (options.getFullEvaluationCount() == 0 ? "\n  full evaluation test off" : ""));
    mcmc.init(options, likelihood, opsched, loggerArray);
    MarkovChain mc = mcmc.getMarkovChain();
    double initialScore = mc.getCurrentScore();
    if (initialScore == Double.NEGATIVE_INFINITY) {
        String message = "The initial posterior is zero";
        if (likelihood instanceof CompoundLikelihood) {
            message += ": " + ((CompoundLikelihood) likelihood).getDiagnosis(2);
        } else {
            message += "!";
        }
        throw new IllegalArgumentException(message);
    }
    if (!xo.getAttribute(SPAWN, true))
        mcmc.setSpawnable(false);
    return mcmc;
}

Example 12 with CompoundLikelihood

use of dr.inference.model.CompoundLikelihood in project beast-mcmc by beast-dev.

the class PMDTestProblem method testPMD.

public void testPMD() throws Exception {
    Parameter popSize = new Parameter.Default(ConstantPopulationModelParser.POPULATION_SIZE, 496432.69917113904, 0, Double.POSITIVE_INFINITY);
    ConstantPopulationModel constantModel = createRandomInitialTree(popSize);
    CoalescentLikelihood coalescent = new CoalescentLikelihood(treeModel, null, new ArrayList<TaxonList>(), constantModel);
    coalescent.setId("coalescent");
    // clock model
    Parameter rateParameter = new Parameter.Default(StrictClockBranchRates.RATE, 4.0E-7, 0, 100.0);
    StrictClockBranchRates branchRateModel = new StrictClockBranchRates(rateParameter);
    // Sub model
    Parameter freqs = new Parameter.Default(new double[] { 0.25, 0.25, 0.25, 0.25 });
    Parameter kappa = new Parameter.Default(HKYParser.KAPPA, 1.0, 1.0E-8, Double.POSITIVE_INFINITY);
    FrequencyModel f = new FrequencyModel(Nucleotides.INSTANCE, freqs);
    HKY hky = new HKY(kappa, f);
    //siteModel
    GammaSiteModel siteModel = new GammaSiteModel(hky);
    Parameter mu = new Parameter.Default(GammaSiteModelParser.MUTATION_RATE, 1.0, 0, Double.POSITIVE_INFINITY);
    siteModel.setMutationRateParameter(mu);
    // SequenceErrorModel
    Parameter ageRelatedRateParameter = new Parameter.Default(SequenceErrorModelParser.AGE_RELATED_RATE, 4.0E-7, 0, 100.0);
    TipStatesModel aDNADamageModel = new SequenceErrorModel(null, null, SequenceErrorModel.ErrorType.TRANSITIONS_ONLY, null, ageRelatedRateParameter, null);
    //treeLikelihood
    SitePatterns patterns = new SitePatterns(alignment, null, 0, -1, 1, true);
    TreeLikelihood treeLikelihood = new TreeLikelihood(patterns, treeModel, siteModel, branchRateModel, aDNADamageModel, false, false, true, false, false);
    treeLikelihood.setId(TreeLikelihoodParser.TREE_LIKELIHOOD);
    // Operators
    OperatorSchedule schedule = new SimpleOperatorSchedule();
    MCMCOperator operator = new ScaleOperator(kappa, 0.75);
    operator.setWeight(1.0);
    schedule.addOperator(operator);
    operator = new ScaleOperator(rateParameter, 0.75);
    operator.setWeight(3.0);
    schedule.addOperator(operator);
    Parameter allInternalHeights = treeModel.createNodeHeightsParameter(true, true, false);
    operator = new UpDownOperator(new Scalable[] { new Scalable.Default(rateParameter) }, new Scalable[] { new Scalable.Default(allInternalHeights) }, 0.75, 3.0, CoercionMode.COERCION_ON);
    schedule.addOperator(operator);
    operator = new ScaleOperator(popSize, 0.75);
    operator.setWeight(3.0);
    schedule.addOperator(operator);
    operator = new ScaleOperator(ageRelatedRateParameter, 0.75);
    operator.setWeight(3.0);
    schedule.addOperator(operator);
    Parameter rootHeight = treeModel.getRootHeightParameter();
    rootHeight.setId(TREE_HEIGHT);
    operator = new ScaleOperator(rootHeight, 0.75);
    operator.setWeight(3.0);
    schedule.addOperator(operator);
    Parameter internalHeights = treeModel.createNodeHeightsParameter(false, true, false);
    operator = new UniformOperator(internalHeights, 30.0);
    schedule.addOperator(operator);
    operator = new SubtreeSlideOperator(treeModel, 15.0, 49643.2699171139, true, false, false, false, CoercionMode.COERCION_ON);
    schedule.addOperator(operator);
    operator = new ExchangeOperator(ExchangeOperator.NARROW, treeModel, 15.0);
    //        operator.doOperation();
    schedule.addOperator(operator);
    operator = new ExchangeOperator(ExchangeOperator.WIDE, treeModel, 3.0);
    //        operator.doOperation();
    schedule.addOperator(operator);
    operator = new WilsonBalding(treeModel, 3.0);
    //        operator.doOperation();
    schedule.addOperator(operator);
    // ??? correct?
    operator = new DeltaExchangeOperator(freqs, new int[] { 1, 1, 1, 1 }, 0.01, 1.0, false, CoercionMode.COERCION_ON);
    schedule.addOperator(operator);
    //CompoundLikelihood
    OneOnXPrior likelihood1 = new OneOnXPrior();
    likelihood1.addData(popSize);
    OneOnXPrior likelihood2 = new OneOnXPrior();
    likelihood2.addData(kappa);
    List<Likelihood> likelihoods = new ArrayList<Likelihood>();
    likelihoods.add(likelihood1);
    likelihoods.add(likelihood2);
    likelihoods.add(coalescent);
    Likelihood prior = new CompoundLikelihood(0, likelihoods);
    prior.setId(CompoundLikelihoodParser.PRIOR);
    likelihoods.clear();
    likelihoods.add(treeLikelihood);
    Likelihood likelihood = new CompoundLikelihood(-1, likelihoods);
    likelihoods.clear();
    likelihoods.add(prior);
    likelihoods.add(likelihood);
    Likelihood posterior = new CompoundLikelihood(0, likelihoods);
    posterior.setId(CompoundLikelihoodParser.POSTERIOR);
    // Log
    ArrayLogFormatter formatter = new ArrayLogFormatter(false);
    MCLogger[] loggers = new MCLogger[2];
    loggers[0] = new MCLogger(formatter, 1000, false);
    loggers[0].add(posterior);
    loggers[0].add(treeLikelihood);
    loggers[0].add(rootHeight);
    loggers[0].add(rateParameter);
    loggers[0].add(ageRelatedRateParameter);
    loggers[0].add(popSize);
    loggers[0].add(kappa);
    loggers[0].add(coalescent);
    loggers[1] = new MCLogger(new TabDelimitedFormatter(System.out), 10000, false);
    loggers[1].add(posterior);
    loggers[1].add(treeLikelihood);
    loggers[1].add(rootHeight);
    loggers[1].add(rateParameter);
    // MCMC
    MCMC mcmc = new MCMC("mcmc1");
    MCMCOptions options = new MCMCOptions(1000000);
    mcmc.setShowOperatorAnalysis(true);
    mcmc.init(options, posterior, schedule, loggers);
    mcmc.run();
    // time
    System.out.println(mcmc.getTimer().toString());
    // Tracer
    List<Trace> traces = formatter.getTraces();
    ArrayTraceList traceList = new ArrayTraceList("PMDTest", traces, 0);
    for (int i = 1; i < traces.size(); i++) {
        traceList.analyseTrace(i);
    }
    //        <expectation name="clock.rate" value="1.5E-7"/>
    //        <expectation name="errorModel.ageRate" value="0.7E-7"/>
    //        <expectation name="hky.kappa" value="10"/>
    TraceCorrelation kappaStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(HKYParser.KAPPA));
    assertExpectation(HKYParser.KAPPA, kappaStats, 10);
    TraceCorrelation rateStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(StrictClockBranchRates.RATE));
    assertExpectation(StrictClockBranchRates.RATE, rateStats, 1.5E-7);
    TraceCorrelation ageRateStats = traceList.getCorrelationStatistics(traceList.getTraceIndex(SequenceErrorModelParser.AGE_RELATED_RATE));
    assertExpectation(SequenceErrorModelParser.AGE_RELATED_RATE, ageRateStats, 0.7E-7);
}