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Example 1 with FilterMetric

use of org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric in project EnrichmentMapApp by BaderLab.

the class PAKnownSignatureCommandTask method loadGeneSets.

private void loadGeneSets(EnrichmentMap map) {
    FilterMetric filterMetric = new FilterMetric.None();
    LoadSignatureSetsActionListener loadAction = loadSignatureSetsActionListenerFactory.create(gmtFile, filterMetric, map);
    loadAction.setGeneSetCallback(gs -> {
        signatureGenesets = gs;
    });
    loadAction.setFilteredSignatureSetsCallback(names -> {
        selectedGenesetNames = names;
    });
    loadAction.actionPerformed(null);
}
Also used : LoadSignatureSetsActionListener(org.baderlab.csplugins.enrichmentmap.actions.LoadSignatureSetsActionListener) FilterMetric(org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric)

Example 2 with FilterMetric

use of org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric in project EnrichmentMapApp by BaderLab.

the class PostAnalysisKnownSignaturePanel method isReady.

public boolean isReady() {
    String filePath = (String) knownSignatureGMTFileNameTextField.getValue();
    if (filePath == null)
        return false;
    // Load in the GMT file
    // Manually fire the same action listener that is used by the signature discovery panel.
    // Use the synchronousTaskManager so that this blocks
    FilterMetric filterMetric = new FilterMetric.None();
    LoadSignatureSetsActionListener loadAction = loadSignatureSetsActionListenerFactory.create(new File(filePath), filterMetric, parentPanel.getEnrichmentMap());
    loadAction.setGeneSetCallback(gs -> {
        this.signatureGenesets = gs;
    });
    loadAction.setFilteredSignatureSetsCallback(selected -> {
        this.selectedGenesetNames = selected;
    });
    loadAction.actionPerformed(null);
    return true;
}
Also used : LoadSignatureSetsActionListener(org.baderlab.csplugins.enrichmentmap.actions.LoadSignatureSetsActionListener) File(java.io.File) FilterMetric(org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric)

Example 3 with FilterMetric

use of org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric in project EnrichmentMapApp by BaderLab.

the class PostAnalysisSignatureDiscoveryPanel method createSignatureDiscoveryGMTPanel.

/**
     * @return Panel for choosing and loading GMT and SignatureGMT Geneset-Files 
     */
private JPanel createSignatureDiscoveryGMTPanel() {
    signatureDiscoveryGMTFileNameTextField = new JFormattedTextField();
    signatureDiscoveryGMTFileNameTextField.setColumns(15);
    signatureDiscoveryGMTFileNameTextField.setToolTipText(Messages.GMT_INSTRUCTION);
    final Color textFieldForeground = signatureDiscoveryGMTFileNameTextField.getForeground();
    signatureDiscoveryGMTFileNameTextField.addPropertyChangeListener("value", (PropertyChangeEvent e) -> {
        // if the text is red set it back to black as soon as the user starts typing
        signatureDiscoveryGMTFileNameTextField.setForeground(textFieldForeground);
    });
    JButton selectSigGMTFileButton = new JButton("Browse...");
    selectSigGMTFileButton.setToolTipText(Messages.GMT_INSTRUCTION);
    selectSigGMTFileButton.setActionCommand("Signature Discovery");
    selectSigGMTFileButton.addActionListener((ActionEvent evt) -> {
        parentPanel.chooseGMTFile(signatureDiscoveryGMTFileNameTextField);
    });
    JLabel filterLabel = new JLabel("Filter:");
    filterTextField = new JFormattedTextField();
    filterTextField.setColumns(4);
    filterTextField.setHorizontalAlignment(JTextField.RIGHT);
    filterTextField.addPropertyChangeListener("value", (PropertyChangeEvent e) -> {
        StringBuilder message = new StringBuilder("The value you have entered is invalid.\n");
        Number number = (Number) filterTextField.getValue();
        PostAnalysisFilterType filterType = getFilterType();
        Optional<Double> value = PostAnalysisInputPanel.validateAndGetFilterValue(number, filterType, message);
        savedFilterValues.put(filterType, value.orElse(filterType.defaultValue));
        if (!value.isPresent()) {
            filterTextField.setValue(filterType.defaultValue);
            JOptionPane.showMessageDialog(application.getJFrame(), message.toString(), "Parameter out of bounds", JOptionPane.WARNING_MESSAGE);
        }
    });
    // Types of filters:
    // 1. filter by percent, i.e. the overlap between the signature geneset and EM geneset
    //    has to be X percentage of the EM set it overlaps with for at least one geneset in the enrichment map.
    // 2. filter by number, i.e. the overlap between the signature geneset and EM geneset
    //    has to be X genes of the EM set it overlaps with for at least one geneset in the enrichment map.
    // 3. filter by specificity, i.e looking for the signature genesets that are more specific than other genesets
    //    for instance a drug A that targets only X and Y as opposed to drug B that targets X,y,L,M,N,O,P.
    filterTypeCombo = new JComboBox<>();
    // default
    filterTypeCombo.addItem(PostAnalysisFilterType.NO_FILTER);
    //		filterTypeCombo.addItem(PostAnalysisFilterType.MANN_WHIT_TWO_SIDED);
    //		filterTypeCombo.addItem(PostAnalysisFilterType.MANN_WHIT_GREATER);
    //		filterTypeCombo.addItem(PostAnalysisFilterType.MANN_WHIT_LESS);
    filterTypeCombo.addItem(PostAnalysisFilterType.HYPERGEOM);
    filterTypeCombo.addItem(PostAnalysisFilterType.NUMBER);
    filterTypeCombo.addItem(PostAnalysisFilterType.PERCENT);
    filterTypeCombo.addItem(PostAnalysisFilterType.SPECIFIC);
    filterTypeCombo.addActionListener(e -> {
        updateFilterTextField();
    });
    updateFilterTextField();
    //TODO: Maybe move loading SigGMT to File-selection Event add load button
    JButton loadButton = new JButton();
    loadButton.setText("Load Gene Sets");
    loadButton.addActionListener(e -> {
        String filePath = (String) signatureDiscoveryGMTFileNameTextField.getValue();
        if (filePath == null || PostAnalysisInputPanel.checkFile(filePath).equals(Color.RED)) {
            String message = "Signature GMT file name not valid.\n";
            signatureDiscoveryGMTFileNameTextField.setForeground(Color.RED);
            JOptionPane.showMessageDialog(application.getJFrame(), message, "Post Analysis Known Signature", JOptionPane.WARNING_MESSAGE);
            return;
        }
        if (!EnrichmentMapParameters.checkFile(filePath)) {
            String message = "Signature GMT does not exist.\n";
            signatureDiscoveryGMTFileNameTextField.setForeground(Color.RED);
            JOptionPane.showMessageDialog(application.getJFrame(), message, "Post Analysis Known Signature", JOptionPane.WARNING_MESSAGE);
            return;
        }
        FilterMetric filterMetric = createFilterMetric();
        LoadSignatureSetsActionListener action = loadSignatureSetsActionListenerFactory.create(new File(filePath), filterMetric, parentPanel.getEnrichmentMap());
        action.setGeneSetCallback(gs -> {
            this.signatureGenesets = gs;
        });
        action.setFilteredSignatureSetsCallback(selected -> {
            availSigSetsModel.clear();
            selectedSigSetsModel.clear();
            for (String name : selected) availSigSetsModel.addElement(name);
            update();
        });
        action.actionPerformed(null);
    });
    makeSmall(signatureDiscoveryGMTFileNameTextField, selectSigGMTFileButton);
    makeSmall(filterLabel, filterTypeCombo, filterTextField);
    makeSmall(loadButton);
    JPanel panel = new JPanel();
    panel.setBorder(LookAndFeelUtil.createTitledBorder("SigGMT File (contains signature-genesets)"));
    final GroupLayout layout = new GroupLayout(panel);
    panel.setLayout(layout);
    layout.setAutoCreateContainerGaps(true);
    layout.setAutoCreateGaps(!LookAndFeelUtil.isAquaLAF());
    layout.setHorizontalGroup(layout.createParallelGroup(Alignment.CENTER, true).addGroup(layout.createSequentialGroup().addComponent(signatureDiscoveryGMTFileNameTextField, DEFAULT_SIZE, DEFAULT_SIZE, Short.MAX_VALUE).addComponent(selectSigGMTFileButton, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE)).addGroup(layout.createSequentialGroup().addComponent(filterLabel, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE).addComponent(filterTypeCombo, DEFAULT_SIZE, DEFAULT_SIZE, Short.MAX_VALUE).addComponent(filterTextField, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE)).addComponent(loadButton, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE));
    layout.setVerticalGroup(layout.createSequentialGroup().addGroup(layout.createParallelGroup(Alignment.CENTER, false).addComponent(signatureDiscoveryGMTFileNameTextField, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE).addComponent(selectSigGMTFileButton)).addGroup(layout.createParallelGroup(Alignment.CENTER, false).addComponent(filterLabel, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE).addComponent(filterTypeCombo, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE).addComponent(filterTextField, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE)).addComponent(loadButton, PREFERRED_SIZE, DEFAULT_SIZE, PREFERRED_SIZE));
    if (LookAndFeelUtil.isAquaLAF())
        panel.setOpaque(false);
    return panel;
}
Also used : JPanel(javax.swing.JPanel) PropertyChangeEvent(java.beans.PropertyChangeEvent) PostAnalysisFilterType(org.baderlab.csplugins.enrichmentmap.model.PostAnalysisFilterType) ActionEvent(java.awt.event.ActionEvent) Color(java.awt.Color) JFormattedTextField(javax.swing.JFormattedTextField) JButton(javax.swing.JButton) JLabel(javax.swing.JLabel) FilterMetric(org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric) LoadSignatureSetsActionListener(org.baderlab.csplugins.enrichmentmap.actions.LoadSignatureSetsActionListener) GroupLayout(javax.swing.GroupLayout) File(java.io.File)

Aggregations

LoadSignatureSetsActionListener (org.baderlab.csplugins.enrichmentmap.actions.LoadSignatureSetsActionListener)3 FilterMetric (org.baderlab.csplugins.enrichmentmap.task.postanalysis.FilterMetric)3 File (java.io.File)2 Color (java.awt.Color)1 ActionEvent (java.awt.event.ActionEvent)1 PropertyChangeEvent (java.beans.PropertyChangeEvent)1 GroupLayout (javax.swing.GroupLayout)1 JButton (javax.swing.JButton)1 JFormattedTextField (javax.swing.JFormattedTextField)1 JLabel (javax.swing.JLabel)1 JPanel (javax.swing.JPanel)1 PostAnalysisFilterType (org.baderlab.csplugins.enrichmentmap.model.PostAnalysisFilterType)1