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Example 11 with AnnotationEvidence

use of org.nextprot.api.core.domain.annotation.AnnotationEvidence in project nextprot-api by calipho-sib.

the class AnnotationTest method testEmptyExpressionLevel.

@Test
public void testEmptyExpressionLevel() {
    Annotation a = new Annotation();
    List<AnnotationEvidence> evidences = new ArrayList<>();
    evidences.add(buildEvidence(""));
    a.setEvidences(evidences);
    Assert.assertTrue(a.isExpressionLevelDetected().isPresent());
    Assert.assertTrue(!a.isExpressionLevelDetected().get());
}
Also used : AnnotationEvidence(org.nextprot.api.core.domain.annotation.AnnotationEvidence) ArrayList(java.util.ArrayList) Annotation(org.nextprot.api.core.domain.annotation.Annotation) Test(org.junit.Test)

Example 12 with AnnotationEvidence

use of org.nextprot.api.core.domain.annotation.AnnotationEvidence in project nextprot-api by calipho-sib.

the class AnnotationTest method testOneHigh.

@Test
public void testOneHigh() {
    Annotation a = new Annotation();
    List<AnnotationEvidence> evidences = new ArrayList<>();
    evidences.add(buildEvidence("high"));
    a.setEvidences(evidences);
    Assert.assertTrue(a.isExpressionLevelDetected().isPresent());
}
Also used : AnnotationEvidence(org.nextprot.api.core.domain.annotation.AnnotationEvidence) ArrayList(java.util.ArrayList) Annotation(org.nextprot.api.core.domain.annotation.Annotation) Test(org.junit.Test)

Example 13 with AnnotationEvidence

use of org.nextprot.api.core.domain.annotation.AnnotationEvidence in project nextprot-api by calipho-sib.

the class AnnotationFieldBuilder method init.

@Override
protected void init(Entry entry) {
    // Function with canonical first
    List<String> function_canonical = EntryUtils.getFunctionInfoWithCanonicalFirst(entry);
    for (String finfo : function_canonical) {
        addField(Fields.FUNCTION_DESC, finfo);
        addField(Fields.ANNOTATIONS, finfo);
    }
    List<Annotation> annots = entry.getAnnotations();
    for (Annotation currannot : annots) {
        String category = currannot.getCategory();
        AnnotationCategory apiCategory = currannot.getAPICategory();
        String quality = currannot.getQualityQualifier();
        if (apiCategory.equals(AnnotationCategory.FUNCTION_INFO) || apiCategory.equals(AnnotationCategory.EXPRESSION_PROFILE))
            // and tissue specificity values are indexed under other fields
            continue;
        // We also should exclude uninformative category 'sequence conflict'
        // if(!category.equals("tissue specificity")) {//These values are
        // indexed under other fields
        // if(!apiCategory.equals(AnnotationCategory.) {//These values are
        // indexed under other fields
        String desc = currannot.getDescription();
        if (apiCategory.equals(AnnotationCategory.GLYCOSYLATION_SITE)) {
            String xref = currannot.getSynonym();
            if (xref != null)
                // It is actually not a synonym but the carbohydrate id from
                // glycosuitedb !
                addField(Fields.ANNOTATIONS, xref);
        } else if (apiCategory.equals(AnnotationCategory.DNA_BINDING_REGION))
            addField(Fields.ANNOTATIONS, category);
        else if (apiCategory.equals(AnnotationCategory.VARIANT))
            // We need to index them somehow for the GOLD/SILVER tests, or
            // do we ? in creates a lot of useless 'variant null' tokens
            desc = "Variant " + desc;
        if (desc != null) {
            // System.err.println(category + ": " + desc);
            if (apiCategory.equals(AnnotationCategory.SEQUENCE_CAUTION)) {
                int stringpos = 0;
                // The sequence
                desc = desc.split(":")[1].substring(1);
                // AAH70170 differs
                // from that shown.
                // Reason:
                // miscellaneous
                // discrepancy
                String[] desclevels = desc.split("\\.");
                String mainreason = desclevels[0];
                if ((stringpos = mainreason.indexOf(" at position")) != -1) {
                    // truncate the position
                    mainreason = mainreason.substring(0, stringpos);
                }
                addField(Fields.ANNOTATIONS, mainreason);
                if (desclevels.length > 1) {
                    if (// mainreason truncated
                    stringpos > 0)
                        desc = desc.substring(desc.indexOf(".") + 2);
                    else {
                        stringpos = desc.indexOf(mainreason) + mainreason.length();
                        desc = desc.substring(stringpos + 2);
                    }
                    addField(Fields.ANNOTATIONS, desc);
                }
            }
            if (!category.startsWith("go") && desc.length() > 1) {
                // description
                if (!this.isGold() || quality.equals("GOLD")) {
                    if (apiCategory.equals(AnnotationCategory.PHENOTYPIC_VARIATION)) {
                        // Get BED data (also get the notes ? )
                        Map<String, AnnotationIsoformSpecificity> annotSpecs = currannot.getTargetingIsoformsMap();
                        for (Map.Entry<String, AnnotationIsoformSpecificity> mapentry : annotSpecs.entrySet()) {
                            String subjectName = mapentry.getValue().getName();
                            // update description with the subject for each
                            // target isofotm
                            addField(Fields.ANNOTATIONS, subjectName + " " + desc);
                        // System.err.println("adding: " + subjectName +
                        // " " + desc);
                        }
                    } else
                        addField(Fields.ANNOTATIONS, desc);
                }
            }
        // in pathway and disease new annotations may appear due to
        // transformation of specific xrefs (orphanet...) into
        // annotations in the api
        }
        handleAnnotationTerm(currannot, entry);
        if (apiCategory.equals(AnnotationCategory.MATURE_PROTEIN) || apiCategory.equals(AnnotationCategory.MATURATION_PEPTIDE)) {
            String chainid = currannot.getSynonym();
            if (chainid != null) {
                // " synonyms: " + currannot.getAllSynonyms());
                if (chainid.contains("-"))
                    // Uniprot FT id,
                    addField(Fields.ANNOTATIONS, chainid);
                else // like
                // PRO_0000019235,
                // shouldn't be
                // called a
                // synonym
                {
                    List<String> chainsynonyms = currannot.getSynonyms();
                    if (chainsynonyms.size() == 1)
                        addField(Fields.ANNOTATIONS, StringUtils.getSortedValueFromPipeSeparatedField(desc + " | " + chainid));
                    else {
                        chainid = "";
                        for (String syno : chainsynonyms) {
                            chainid += syno + " | ";
                        }
                        addField(Fields.ANNOTATIONS, StringUtils.getSortedValueFromPipeSeparatedField(chainid));
                    }
                }
            }
        // else System.err.println("chainid null for: " + desc);
        // chainid 's null for the main chain, this is wrong
        }
        // variant xrefs and identifiers
        if (apiCategory.equals(AnnotationCategory.VARIANT)) {
            String evidxrefaccs = "";
            List<AnnotationEvidence> evidences = currannot.getEvidences();
            if (evidences != null)
                for (AnnotationEvidence ev : evidences) {
                    if (ev.isResourceAXref()) {
                        String db = ev.getResourceDb();
                        if (db == null)
                            System.err.println("db is null for evidence in variant annot: " + desc);
                        else {
                            if (!evidxrefaccs.isEmpty())
                                evidxrefaccs += " | ";
                            if (db.equals("Cosmic"))
                                evidxrefaccs += db.toLowerCase() + ":" + ev.getResourceAccession();
                            else if (// Just to allow
                            db.equals("dbSNP"))
                                // comparison with
                                // incoherent
                                // current solr
                                // implementation
                                evidxrefaccs += ev.getResourceAccession();
                            else
                                // Uniprot
                                evidxrefaccs += currannot.getSynonym();
                        // FT
                        // id,
                        // like
                        // VAR_056577
                        }
                    }
                }
            if (!this.isGold() || quality.equals("GOLD")) {
                if (!evidxrefaccs.isEmpty())
                    addField(Fields.ANNOTATIONS, StringUtils.getSortedValueFromPipeSeparatedField(evidxrefaccs));
                Collection<AnnotationProperty> props = currannot.getProperties();
                for (AnnotationProperty prop : props) if (prop.getName().equals("mutation AA"))
                    // eg: p.D1685E, it is unclear why this property
                    // exists only in cosmic variants
                    addField(Fields.ANNOTATIONS, prop.getValue());
            }
        }
    }
    // Families (why not part of Annotations ?), always GOLD
    for (Family family : entry.getOverview().getFamilies()) {
        String ac = family.getAccession();
        int stringpos = 0;
        addField(Fields.ANNOTATIONS, ac);
        String famdesc = family.getDescription();
        // There is no get_synonyms() method for families -> can't access
        // PERVR for FA-04785
        addField(Fields.ANNOTATIONS, famdesc);
        stringpos = famdesc.indexOf("elongs to ") + 14;
        // Skip the 'Belongs to' and
        famdesc = famdesc.substring(stringpos);
        // what may come before (eg:
        // NX_P19021)
        // remove
        famdesc = famdesc.substring(0, famdesc.length() - 1);
        // final dot
        addField(Fields.ANNOTATIONS, famdesc);
        // are there subfamilies
        String[] families = famdesc.split("\\. ");
        // ?
        if (families.length > 1) {
            // Always GOLD
            for (int i = 0; i < families.length; i++) {
                addField(Fields.ANNOTATIONS, families[i]);
                if (families[i].contains(") superfamily")) {
                    // index one
                    // more time
                    // without
                    // parenthesis
                    famdesc = families[i].substring(0, families[i].indexOf("(")) + "superfamily";
                    addField(Fields.ANNOTATIONS, famdesc);
                }
            }
        }
        // Sonetimes these synonymes are wrong eg: NX_Q6NUT3 -> Major
        // facilitator (TC 2.A.1) superfamily
        List<String> famsynonyms = this.terminologyservice.findCvTermByAccession(ac).getSynonyms();
        if (famsynonyms != null)
            for (String famsynonym : famsynonyms) addField(Fields.ANNOTATIONS, famsynonym.trim());
    }
}
Also used : AnnotationCategory(org.nextprot.api.commons.constants.AnnotationCategory) Annotation(org.nextprot.api.core.domain.annotation.Annotation) AnnotationEvidence(org.nextprot.api.core.domain.annotation.AnnotationEvidence) AnnotationProperty(org.nextprot.api.core.domain.annotation.AnnotationProperty) AnnotationIsoformSpecificity(org.nextprot.api.core.domain.annotation.AnnotationIsoformSpecificity) Family(org.nextprot.api.core.domain.Family) Map(java.util.Map)

Example 14 with AnnotationEvidence

use of org.nextprot.api.core.domain.annotation.AnnotationEvidence in project nextprot-api by calipho-sib.

the class PeptideMappingDaoImpl method findPeptideAnnotationEvidencesMap.

@Override
public Map<String, List<AnnotationEvidence>> findPeptideAnnotationEvidencesMap(List<String> names, boolean natural) {
    String datasourceClause = natural ? " ds.cv_name != 'SRMAtlas'" : " ds.cv_name  = 'SRMAtlas'";
    final AnnotationMapping2Annotation pmam = natural ? AnnotationMapping2Annotation.PEPTIDE_MAPPING : AnnotationMapping2Annotation.SRM_PEPTIDE_MAPPING;
    String sql = sqlDictionary.getSQLQuery("peptide-evidences-by-peptide-names").replace(":datasourceClause", datasourceClause);
    Map<String, Object> params = new HashMap<String, Object>();
    params.put("names", names);
    SqlParameterSource namedParams = new MapSqlParameterSource(params);
    List<AnnotationEvidence> evidences = new NamedParameterJdbcTemplate(dsLocator.getDataSource()).query(sql, namedParams, new RowMapper<AnnotationEvidence>() {

        @Override
        public AnnotationEvidence mapRow(ResultSet resultSet, int row) throws SQLException {
            AnnotationEvidence evidence = new AnnotationEvidence();
            // set later by service
            evidence.setAnnotationId(0);
            evidence.setEvidenceId(resultSet.getLong("evidence_id") + IdentifierOffset.PEPTIDE_MAPPING_ANNOTATION_EVIDENCE_OFFSET);
            evidence.setAssignedBy(resultSet.getString("assigned_by"));
            evidence.setAssignmentMethod(pmam.getAssignmentMethod());
            evidence.setEvidenceCodeAC(pmam.getEcoAC());
            evidence.setEvidenceCodeOntology(pmam.getEcoOntology());
            evidence.setEvidenceCodeName(pmam.getEcoName());
            evidence.setExperimentalContextId(null);
            evidence.setNegativeEvidence(false);
            evidence.setProperties(new ArrayList<AnnotationEvidenceProperty>());
            evidence.setQualifierType(pmam.getQualifierType());
            evidence.setQualityQualifier(pmam.getQualityQualifier());
            evidence.setResourceAccession(resultSet.getString("accession"));
            evidence.setResourceAssociationType("evidence");
            evidence.setResourceDb(resultSet.getString("database_name"));
            // temp value
            evidence.setResourceDescription(resultSet.getString("unique_name"));
            evidence.setResourceId(resultSet.getLong("resource_id"));
            evidence.setResourceType(resultSet.getString("resource_type"));
            return evidence;
        }
    });
    // turn this list into a map having the peptide name as the key
    Map<String, List<AnnotationEvidence>> result = new HashMap<>();
    for (AnnotationEvidence ev : evidences) {
        String pepKey = ev.getResourceDescription();
        // remove temp value
        ev.setResourceDescription(null);
        if (!result.containsKey(pepKey))
            result.put(pepKey, new ArrayList<AnnotationEvidence>());
        result.get(pepKey).add(ev);
    }
    return result;
}
Also used : HashMap(java.util.HashMap) NamedParameterJdbcTemplate(org.springframework.jdbc.core.namedparam.NamedParameterJdbcTemplate) SQLException(java.sql.SQLException) AnnotationMapping2Annotation(org.nextprot.api.commons.constants.AnnotationMapping2Annotation) ArrayList(java.util.ArrayList) AnnotationEvidence(org.nextprot.api.core.domain.annotation.AnnotationEvidence) MapSqlParameterSource(org.springframework.jdbc.core.namedparam.MapSqlParameterSource) SqlParameterSource(org.springframework.jdbc.core.namedparam.SqlParameterSource) MapSqlParameterSource(org.springframework.jdbc.core.namedparam.MapSqlParameterSource) ResultSet(java.sql.ResultSet) ArrayList(java.util.ArrayList) List(java.util.List)

Example 15 with AnnotationEvidence

use of org.nextprot.api.core.domain.annotation.AnnotationEvidence in project nextprot-api by calipho-sib.

the class AnnotationUtils method convertRelativeEvidenceToProperty.

private static List<AnnotationEvidence> convertRelativeEvidenceToProperty(Annotation annot, String propertyName) {
    List<AnnotationEvidence> toRemove = new ArrayList<>();
    for (AnnotationEvidence evi : annot.getEvidences()) {
        if ("relative".equals(evi.getResourceAssociationType())) {
            AnnotationProperty p = new AnnotationProperty();
            p.setAnnotationId(annot.getAnnotationId());
            p.setAccession(evi.getResourceAccession());
            p.setName(propertyName);
            p.setValue(Long.toString(evi.getResourceId()));
            p.setValueType(PropertyApiModel.VALUE_TYPE_RIF);
            annot.addProperties(Arrays.asList(p));
            toRemove.add(evi);
        }
    }
    return toRemove;
}
Also used : AnnotationEvidence(org.nextprot.api.core.domain.annotation.AnnotationEvidence) AnnotationProperty(org.nextprot.api.core.domain.annotation.AnnotationProperty)

Aggregations

AnnotationEvidence (org.nextprot.api.core.domain.annotation.AnnotationEvidence)39 Annotation (org.nextprot.api.core.domain.annotation.Annotation)28 Test (org.junit.Test)23 ArrayList (java.util.ArrayList)16 CoreUnitBaseTest (org.nextprot.api.core.test.base.CoreUnitBaseTest)11 AnnotationIsoformSpecificity (org.nextprot.api.core.domain.annotation.AnnotationIsoformSpecificity)7 CvTerm (org.nextprot.api.core.domain.CvTerm)6 AnnotationCategory (org.nextprot.api.commons.constants.AnnotationCategory)5 Collectors (java.util.stream.Collectors)4 BioObject (org.nextprot.api.core.domain.BioObject)4 java.util (java.util)3 List (java.util.List)3 NextProtException (org.nextprot.api.commons.exception.NextProtException)3 DbXref (org.nextprot.api.core.domain.DbXref)3 AnnotationEvidenceProperty (org.nextprot.api.core.domain.annotation.AnnotationEvidenceProperty)3 AnnotationProperty (org.nextprot.api.core.domain.annotation.AnnotationProperty)3 Supplier (com.google.common.base.Supplier)2 Logger (org.apache.log4j.Logger)2 IdentifierOffset (org.nextprot.api.commons.constants.IdentifierOffset)2 StringUtils (org.nextprot.api.commons.utils.StringUtils)2