use of org.sbolstandard.core2.GenericTopLevel in project libSBOLj by SynBioDex.
the class RepressionModel method main.
public static void main(String[] args) throws SBOLValidationException, SBOLConversionException, IOException {
SBOLDocument doc = new SBOLDocument();
doc.setDefaultURIprefix("http://sbols.org/CRISPR_Example/");
doc.setComplete(true);
doc.setCreateDefaults(true);
String version = "1.0.0";
// Create ComponentDefinition for cas9_generic protein
doc.createComponentDefinition("cas9_generic", version, ComponentDefinition.PROTEIN);
// Create ComponentDefinition for gRNA_generic RNA
doc.createComponentDefinition("gRNA_generic", version, ComponentDefinition.RNA).addRole(SequenceOntology.SGRNA);
// Create ComponentDefinition for cas9_gRNA_complex
doc.createComponentDefinition("cas9_gRNA_complex", version, ComponentDefinition.COMPLEX);
// Create ComponentDefinition for target gene
doc.createComponentDefinition("target_gene", version, ComponentDefinition.DNA).addRole(SequenceOntology.PROMOTER);
// Create ComponentDefinition for target protein
doc.createComponentDefinition("target", version, ComponentDefinition.PROTEIN);
// Create ModuleDefinition for CRISPR_Repression_Template
ModuleDefinition CRISPR_Template = doc.createModuleDefinition("CRISPR_Template", version);
// Complex Formation Interaction for Cas9m_BFP and gRNA
Interaction Cas9Complex_Formation = CRISPR_Template.createInteraction("cas9_complex_formation", SystemsBiologyOntology.NON_COVALENT_BINDING);
Cas9Complex_Formation.createParticipation("cas9_generic", "cas9_generic", SystemsBiologyOntology.REACTANT);
Cas9Complex_Formation.createParticipation("gRNA_generic", "gRNA_generic", SystemsBiologyOntology.REACTANT);
Cas9Complex_Formation.createParticipation("cas9_gRNA_complex", "cas9_gRNA_complex", SystemsBiologyOntology.PRODUCT);
// Production of target from target gene
Interaction EYFP_production = CRISPR_Template.createInteraction("target_production", SystemsBiologyOntology.GENETIC_PRODUCTION);
EYFP_production.createParticipation("target_gene", "target_gene", SystemsBiologyOntology.PROMOTER);
EYFP_production.createParticipation("target", "target", SystemsBiologyOntology.PRODUCT);
// Inhibition of target by cas9m_BFP_gRNA
Interaction target_generic_gene_inhibition = CRISPR_Template.createInteraction("target_gene_inhibition", SystemsBiologyOntology.INHIBITION);
target_generic_gene_inhibition.createParticipation("cas9_gRNA_complex", "cas9_gRNA_complex", SystemsBiologyOntology.INHIBITOR);
target_generic_gene_inhibition.createParticipation("target_gene", "target_gene", SystemsBiologyOntology.PROMOTER);
// Create Sequence for CRa_U6 promoter
String CRa_U6_seq_elements = "GGTTTACCGAGCTCTTATTGGTTTTCAAACTTCATTGACTGTGCC" + "AAGGTCGGGCAGGAAGAGGGCCTATTTCCCATGATTCCTTCATAT" + "TTGCATATACGATACAAGGCTGTTAGAGAGATAATTAGAATTAAT" + "TTGACTGTAAACACAAAGATATTAGTACAAAATACGTGACGTAGA" + "AAGTAATAATTTCTTGGGTAGTTTGCAGTTTTAAAATTATGTTTT" + "AAAATGGACTATCATATGCTTACCGTAACTTGAAATATAGAACCG" + "ATCCTCCCATTGGTATATATTATAGAACCGATCCTCCCATTGGCT" + "TGTGGAAAGGACGAAACACCGTACCTCATCAGGAACATGTGTTTA" + "AGAGCTATGCTGGAAACAGCAGAAATAGCAAGTTTAAATAAGGCT" + "AGTCCGTTATCAACTTGAAAAAGTGGCACCGAGTCGGTGCTTTTT" + "TTGGTGCGTTTTTATGCTTGTAGTATTGTATAATGTTTTT";
doc.createSequence("CRa_U6_seq", version, CRa_U6_seq_elements, Sequence.IUPAC_DNA);
// Create Sequence for gRNA_b coding sequence
String gRNA_b_elements = "AAGGTCGGGCAGGAAGAGGGCCTATTTCCCATGATTCCTTCATAT" + "TTGCATATACGATACAAGGCTGTTAGAGAGATAATTAGAATTAAT" + "TTGACTGTAAACACAAAGATATTAGTACAAAATACGTGACGTAGA" + "AAGTAATAATTTCTTGGGTAGTTTGCAGTTTTAAAATTATGTTTT" + "AAAATGGACTATCATATGCTTACCGTAACTTGAAAGTATTTCGAT" + "TTCTTGGCTTTATATATCTTGTGGAAAGGACGAAACACCGTACCT" + "CATCAGGAACATGTGTTTAAGAGCTATGCTGGAAACAGCAGAAAT" + "AGCAAGTTTAAATAAGGCTAGTCCGTTATCAACTTGAAAAAGTGG" + "CACCGAGTCGGTGCTTTTTTT";
doc.createSequence("gRNA_b_seq", version, gRNA_b_elements, Sequence.IUPAC_DNA);
// Create Sequence for mKate
String mKate_seq_elements = "TCTAAGGGCGAAGAGCTGATTAAGGAGAACATGCACATGAAGCTG" + "TACATGGAGGGCACCGTGAACAACCACCACTTCAAGTGCACATCC" + "GAGGGCGAAGGCAAGCCCTACGAGGGCACCCAGACCATGAGAATC" + "AAGGTGGTCGAGGGCGGCCCTCTCCCCTTCGCCTTCGACATCCTG" + "GCTACCAGCTTCATGTACGGCAGCAAAACCTTCATCAACCACACC" + "CAGGGCATCCCCGACTTCTTTAAGCAGTCCTTCCCTGAGGTAAGT" + "GGTCCTACCTCATCAGGAACATGTGTTTTAGAGCTAGAAATAGCA" + "AGTTAAAATAAGGCTAGTCCGTTATCAACTTGAAAAAGTGGCACC" + "GAGTCGGTGCTACTAACTCTCGAGTCTTCTTTTTTTTTTTCACAG" + "GGCTTCACATGGGAGAGAGTCACCACATACGAAGACGGGGGCGTG" + "CTGACCGCTACCCAGGACACCAGCCTCCAGGACGGCTGCCTCATC" + "TACAACGTCAAGATCAGAGGGGTGAACTTCCCATCCAACGGCCCT" + "GTGATGCAGAAGAAAACACTCGGCTGGGAGGCCTCCACCGAGATG" + "CTGTACCCCGCTGACGGCGGCCTGGAAGGCAGAAGCGACATGGCC" + "CTGAAGCTCGTGGGCGGGGGCCACCTGATCTGCAACTTGAAGACC" + "ACATACAGATCCAAGAAACCCGCTAAGAACCTCAAGATGCCCGGC" + "GTCTACTATGTGGACAGAAGACTGGAAAGAATCAAGGAGGCCGAC" + "AAAGAGACCTACGTCGAGCAGCACGAGGTGGCTGTGGCCAGATAC" + "TGCG";
doc.createSequence("mKate_seq", version, mKate_seq_elements, Sequence.IUPAC_DNA);
// Create Sequence for CRP_b promoter
String CRP_b_seq_elements = "GCTCCGAATTTCTCGACAGATCTCATGTGATTACGCCAAGCTACG" + "GGCGGAGTACTGTCCTCCGAGCGGAGTACTGTCCTCCGAGCGGAG" + "TACTGTCCTCCGAGCGGAGTACTGTCCTCCGAGCGGAGTTCTGTC" + "CTCCGAGCGGAGACTCTAGATACCTCATCAGGAACATGTTGGAAT" + "TCTAGGCGTGTACGGTGGGAGGCCTATATAAGCAGAGCTCGTTTA" + "GTGAACCGTCAGATCGCCTCGAGTACCTCATCAGGAACATGTTGG" + "ATCCAATTCGACC";
doc.createSequence("CRP_b_seq", version, CRP_b_seq_elements, Sequence.IUPAC_DNA);
// Create ComponentDefinition for a Constitutive Promoter
doc.createComponentDefinition("pConst", version, ComponentDefinition.DNA).addRole(SequenceOntology.PROMOTER);
// Create ComponentDefinition for cas9m_BFP coding sequence
doc.createComponentDefinition("cas9m_BFP_cds", version, ComponentDefinition.DNA).addRole(SequenceOntology.CDS);
// Create ComponentDefinition for cas9m_BFP gene
ComponentDefinition cas9m_BFP_gene = doc.createComponentDefinition("cas9m_BFP_gene", version, ComponentDefinition.DNA);
cas9m_BFP_gene.addRole(SequenceOntology.PROMOTER);
cas9m_BFP_gene.createSequenceConstraint("cas9m_BFP_gene_constraint", RestrictionType.PRECEDES, "pConst", "cas9m_BFP_cds");
// Create ComponentDefintion for cas9m_BFP protein
doc.createComponentDefinition("cas9m_BFP", version, ComponentDefinition.PROTEIN);
// Create ComponentDefintion for CRa_U6 promoter
ComponentDefinition CRa_U6 = doc.createComponentDefinition("CRa_U6", version, ComponentDefinition.DNA);
CRa_U6.addRole(SequenceOntology.PROMOTER);
CRa_U6.addSequence("CRa_U6_seq");
// Create ComponentDefintion for gRNA_b coding sequence
ComponentDefinition gRNA_b_nc = doc.createComponentDefinition("gRNA_b_nc", version, ComponentDefinition.DNA);
gRNA_b_nc.addRole(SequenceOntology.CDS);
gRNA_b_nc.addSequence("gRNA_b_seq");
// Create ComponentDefinition for gRNA_b terminator
doc.createComponentDefinition("gRNA_b_terminator", version, ComponentDefinition.DNA).addRole(SequenceOntology.TERMINATOR);
// Create ComponentDefinition for gRNA_b gene
ComponentDefinition gRNA_b_gene = doc.createComponentDefinition("gRNA_b_gene", version, ComponentDefinition.DNA);
gRNA_b_gene.addRole(SequenceOntology.PROMOTER);
gRNA_b_gene.createSequenceConstraint("gRNA_b_gene_constraint1", RestrictionType.PRECEDES, "CRa_U6", "gRNA_b_nc");
gRNA_b_gene.createSequenceConstraint("gRNA_b_gene_constraint2", RestrictionType.PRECEDES, "gRNA_b_nc", "gRNA_b_terminator");
// Create ComponentDefinition for gRNA_b RNA
doc.createComponentDefinition("gRNA_b", version, ComponentDefinition.RNA).addRole(SequenceOntology.SGRNA);
SequenceOntology so = new SequenceOntology();
URI sgrna = so.getURIbyName("sgRNA");
// Create ComponentDefinition for cas9m_BFP gRNA_b complex
doc.createComponentDefinition("cas9m_BFP_gRNA_b", version, ComponentDefinition.COMPLEX);
// Create ComponentDefinition for mKate coding sequence
ComponentDefinition mKate_cds = doc.createComponentDefinition("mKate_cds", version, ComponentDefinition.DNA);
mKate_cds.addRole(SequenceOntology.CDS);
mKate_cds.addSequence("mKate_seq");
// Create ComponentDefinition for mKate gene
ComponentDefinition mKate_gene = doc.createComponentDefinition("mKate_gene", version, ComponentDefinition.DNA);
mKate_gene.addRole(SequenceOntology.PROMOTER);
mKate_gene.createSequenceConstraint("mKate_gene_constraint", RestrictionType.PRECEDES, "pConst", "mKate_cds");
// Create ComponentDefinition for mKate protein
doc.createComponentDefinition("mKate", version, ComponentDefinition.PROTEIN);
// Create ComponentDefinition for Gal4VP16 coding sequence
ComponentDefinition Gal4VP16_cds = doc.createComponentDefinition("Gal4VP16_cds", version, ComponentDefinition.DNA);
Gal4VP16_cds.addRole(SequenceOntology.CDS);
// Create ComponentDefintion for Gal4VP16 gene
ComponentDefinition Gal4VP16_gene = doc.createComponentDefinition("Gal4VP16_gene", version, ComponentDefinition.DNA);
Gal4VP16_gene.addRole(SequenceOntology.PROMOTER);
Gal4VP16_gene.createSequenceConstraint("GAL4VP16_gene_constraint", RestrictionType.PRECEDES, "pConst", "Gal4VP16_cds");
// Create ComponentDefintion for Gal4VP16 protein
doc.createComponentDefinition("Gal4VP16", version, ComponentDefinition.PROTEIN);
// Create ComponentDefinition for CRP_b promoter
ComponentDefinition CRP_b = doc.createComponentDefinition("CRP_b", version, ComponentDefinition.DNA);
CRP_b.addRole(SequenceOntology.PROMOTER);
CRP_b.addSequence("CRP_b_seq");
// Create ComponentDefintiion for EYFP coding sequence
ComponentDefinition EYFP_cds = doc.createComponentDefinition("EYFP_cds", version, ComponentDefinition.DNA);
EYFP_cds.addRole(SequenceOntology.CDS);
// Create ComponentDefinition for EYFP gene
ComponentDefinition EYFP_gene = doc.createComponentDefinition("EYFP_gene", version, ComponentDefinition.DNA);
EYFP_gene.addRole(SequenceOntology.PROMOTER);
EYFP_gene.createSequenceConstraint("EYFP_gene_constraint", RestrictionType.PRECEDES, "CRP_b", "EYFP_cds");
// Create ComponentDefintiion for EYFP protein
doc.createComponentDefinition("EYFP", version, ComponentDefinition.PROTEIN);
// Create ModuleDefintion for CRISPR Repression
ModuleDefinition CRPb_circuit = doc.createModuleDefinition("CRPb_characterization_circuit", version);
// Create the FunctionalComponents for the ModuleDefinition CRISPR_Repression
CRPb_circuit.createFunctionalComponent("cas9m_BFP", AccessType.PRIVATE, "cas9m_BFP", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("cas9m_BFP_gene", AccessType.PRIVATE, "cas9m_BFP_gene", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("gRNA_b", AccessType.PRIVATE, "gRNA_b", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("gRNA_b_gene", AccessType.PRIVATE, "gRNA_b_gene", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("mKate", AccessType.PRIVATE, "mKate", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("mKate_gene", AccessType.PRIVATE, "mKate_gene", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("Gal4VP16", AccessType.PRIVATE, "Gal4VP16", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("Gal4VP16_gene", AccessType.PRIVATE, "Gal4VP16_gene", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("EYFP", AccessType.PRIVATE, "EYFP", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("EYFP_gene", AccessType.PRIVATE, "EYFP_gene", version, DirectionType.NONE);
CRPb_circuit.createFunctionalComponent("cas9m_BFP_gRNA_b", AccessType.PRIVATE, "cas9m_BFP_gRNA_b", version, DirectionType.NONE);
/* Production of mKate from the mKate gene */
Interaction mKate_production = CRPb_circuit.createInteraction("mKate_production", SystemsBiologyOntology.GENETIC_PRODUCTION);
mKate_production.createParticipation("mKate", "mKate", SystemsBiologyOntology.PRODUCT);
mKate_production.createParticipation("mKate_gene", "mKate_gene", SystemsBiologyOntology.PROMOTER);
// Production of GAL4VP16 from the GAL4VP16 gene
Interaction GAL4VP16_production = CRPb_circuit.createInteraction("Gal4VP16_production", SystemsBiologyOntology.GENETIC_PRODUCTION);
GAL4VP16_production.createParticipation("Gal4VP16_gene", "Gal4VP16_gene", SystemsBiologyOntology.PROMOTER);
GAL4VP16_production.createParticipation("Gal4VP16", "Gal4VP16", SystemsBiologyOntology.PRODUCT);
// Production of cas9m_BFP from the cas9m_BFP gene
Interaction cas9m_BFP_production = CRPb_circuit.createInteraction("cas9m_BFP_production", SystemsBiologyOntology.GENETIC_PRODUCTION);
cas9m_BFP_production.createParticipation("cas9m_BFP_gene", "cas9m_BFP_gene", SystemsBiologyOntology.PROMOTER);
cas9m_BFP_production.createParticipation("cas9m_BFP", "cas9m_BFP", SystemsBiologyOntology.PRODUCT);
// Production of gRNA_b from the gRNA_b gene
Interaction gRNA_b_production = CRPb_circuit.createInteraction("gRNA_b_production", SystemsBiologyOntology.GENETIC_PRODUCTION);
gRNA_b_production.createParticipation("gRNA_b_gene", "gRNA_b_gene", SystemsBiologyOntology.PROMOTER);
gRNA_b_production.createParticipation("gRNA_b", "gRNA_b", SystemsBiologyOntology.PRODUCT);
// Activation of EYFP production by GAL4VP16
Interaction EYFP_Activation = CRPb_circuit.createInteraction("EYFP_Activation", SystemsBiologyOntology.STIMULATION);
EYFP_Activation.createParticipation("Gal4VP16", "Gal4VP16", SystemsBiologyOntology.STIMULATOR);
EYFP_Activation.createParticipation("EYFP_gene", "EYFP_gene", SystemsBiologyOntology.PROMOTER);
// Degradation of mKate
Interaction mKate_deg = CRPb_circuit.createInteraction("mKate_deg", SystemsBiologyOntology.DEGRADATION);
mKate_deg.createParticipation("mKate", "mKate", SystemsBiologyOntology.REACTANT);
// Degradation of GAL4VP16
Interaction GAL4VP16_deg = CRPb_circuit.createInteraction("Gal4VP16_deg", SystemsBiologyOntology.DEGRADATION);
GAL4VP16_deg.createParticipation("Gal4VP16", "Gal4VP16", SystemsBiologyOntology.REACTANT);
// Degradation of cas9m_BFP
Interaction cas9m_BFP_deg = CRPb_circuit.createInteraction("cas9m_BFP_deg", SystemsBiologyOntology.DEGRADATION);
cas9m_BFP_deg.createParticipation("cas9m_BFP", "cas9m_BFP", SystemsBiologyOntology.REACTANT);
// Degradation of gRNA_b
Interaction gRNA_b_deg = CRPb_circuit.createInteraction("gRNA_b_deg", SystemsBiologyOntology.DEGRADATION);
gRNA_b_deg.createParticipation("gRNA_b", "gRNA_b", SystemsBiologyOntology.REACTANT);
// Degradation of EYFP
Interaction EYFP_deg = CRPb_circuit.createInteraction("EYFP_deg", SystemsBiologyOntology.DEGRADATION);
EYFP_deg.createParticipation("EYFP", "EYFP", SystemsBiologyOntology.REACTANT);
// Degradation of cas9m_BFP_gRNA_b
Interaction cas9m_BFP_gRNA_b_deg = CRPb_circuit.createInteraction("cas9m_BFP_gRNA_b_deg", SystemsBiologyOntology.DEGRADATION);
cas9m_BFP_gRNA_b_deg.createParticipation("cas9m_BFP_gRNA_b", "cas9m_BFP_gRNA_b", SystemsBiologyOntology.REACTANT);
// Create Template Module
Module Template_Module = CRPb_circuit.createModule("CRISPR_Template", "CRISPR_Template", version);
// Add MapsTos to Template Module
Template_Module.createMapsTo("cas9m_BFP_map", RefinementType.USELOCAL, "cas9m_BFP", "cas9_generic");
Template_Module.createMapsTo("gRNA_b_map", RefinementType.USELOCAL, "gRNA_b", "gRNA_generic");
Template_Module.createMapsTo("cas9m_BFP_gRNA_map", RefinementType.USELOCAL, "cas9m_BFP_gRNA_b", "cas9_gRNA_complex");
Template_Module.createMapsTo("EYFP_map", RefinementType.USELOCAL, "EYFP", "target");
Template_Module.createMapsTo("EYFP_gene_map", RefinementType.USELOCAL, "EYFP_gene", "target_gene");
// try {
// SBOLWriter.write(doc, "/Users/myers/RepressionModel.rdf");
// }
// catch (XMLStreamException | FactoryConfigurationError | CoreIoException e) {
// e.printStackTrace();
// }
// catch (IOException e) {
// e.printStackTrace();
// }
// END of Repression Model construction. Code below uses trivial manipulations to show other major methods in the library.
ComponentDefinition cas9_generic1 = doc.getComponentDefinition("cas9_generic", version);
ComponentDefinition cas9_generic2 = doc.getComponentDefinition("cas9_generic", null);
if (cas9_generic1.equals(cas9_generic2)) {
System.out.println("Two Cas9 generic protein objects are equal.");
}
gRNA_b_gene.getSequenceConstraint("gRNA_b_gene_constraint1");
CRISPR_Template.setName("C~R*I!S@P#R-based Repression Template");
if (CRISPR_Template.isSetName()) {
CRISPR_Template.unsetName();
CRISPR_Template.setName("CRISPR-based Repression Template");
}
CRISPR_Template.setDescription("Authors: S. Kiani, J. Beal, M. Ebrahimkhani, J. Huh, R. Hall, Z. Xie, Y. Li, and R. Weiss" + "Titel: Crispr transcriptional repression devices and layered circuits in mammalian cells" + "Journal: Nature Methods, vol. 11, no. 7, pp. 723–726, 2014.");
URI gRNA_b_gene_role2 = URI.create("http://identifiers.org/so/SO:0000613");
gRNA_b_gene.addRole(gRNA_b_gene_role2);
if (gRNA_b_gene.containsRole(gRNA_b_gene_role2)) {
gRNA_b_gene.removeRole(gRNA_b_gene_role2);
}
gRNA_b_gene.clearRoles();
if (!gRNA_b_gene.getRoles().isEmpty()) {
System.out.println("gRNA_b_gene set is not empty.");
}
gRNA_b_gene.setRoles(new HashSet<URI>(Arrays.asList(SequenceOntology.PROMOTER)));
CRP_b.clearSequences();
CRP_b.addSequence("CRP_b_seq");
// CRP_b.addSequence(
// URI.create("http://partsregistry.org/seq/partseq_154")
// );
String prURI = "http://partsregistry.org/";
String prPrefix = "pr";
doc.addNamespace(URI.create(prURI), prPrefix);
ComponentDefinition pConst = doc.getComponentDefinition("pConst", version);
pConst.createAnnotation(new QName(prURI, "experience", prPrefix), URI.create("http://parts.igem.org/Part:BBa_J23119:Experience"));
String myersLabURI = "http://www.async.ece.utah.edu/";
String myersLabPrefix = "myersLab";
doc.addNamespace(URI.create(myersLabURI), myersLabPrefix);
GenericTopLevel datasheet = doc.createGenericTopLevel("datasheet", "1.1", new QName(myersLabURI, "datasheet", myersLabPrefix));
datasheet.setName("Datasheet for Custom Parameters");
datasheet.createAnnotation(new QName(myersLabURI, "characterizationData", myersLabPrefix), URI.create(myersLabURI + "/measurement/BBa_J23119"));
datasheet.createAnnotation(new QName(myersLabURI, "transcriptionRate", myersLabPrefix), 0.75);
pConst.createAnnotation(new QName(myersLabURI, "datasheet", myersLabPrefix), datasheet.getIdentity());
ComponentDefinition pConst_alt = (ComponentDefinition) doc.createCopy(pConst, "pConst_alt");
// pConst_alt.createAnnotation(
// new QName(prURI, "", prPrefix),
// URI.create("http://parts.igem.org/Part:BBa_J23100"));
Sequence pConst_alt_seq = doc.createSequence("pConst_alt_seq", version, "ttgacggctagctcagtcctaggtacagtgctagc", Sequence.IUPAC_DNA);
pConst_alt.addSequence(pConst_alt_seq);
SBOLValidate.validateSBOL(doc, true, true, true);
if (SBOLValidate.getNumErrors() > 0) {
for (String error : SBOLValidate.getErrors()) {
System.out.println(error);
}
return;
}
SBOLWriter.write(doc, (System.out));
SBOLWriter.write(doc, "RepressionModel.rdf");
}
use of org.sbolstandard.core2.GenericTopLevel in project libSBOLj by SynBioDex.
the class GettingStartedExample method main.
public static void main(String[] args) throws IOException, SBOLValidationException, SBOLConversionException {
String prURI = "http://partsregistry.org/";
String prPrefix = "pr";
String myersLabURI = "http://www.async.ece.utah.edu/";
String myersLabPrefix = "myersLab";
SBOLDocument document = new SBOLDocument();
document.setDefaultURIprefix(prURI);
document.setTypesInURIs(true);
document.setComplete(true);
document.setCreateDefaults(true);
document.addNamespace(URI.create(prURI), prPrefix);
document.addNamespace(URI.create(myersLabURI), myersLabPrefix);
// Creating a Top-level SBOL Data Object
HashSet<URI> types = new HashSet<URI>(Arrays.asList(ComponentDefinition.DNA, URI.create("http://identifiers.org/chebi/CHEBI:4705")));
ComponentDefinition TetR_promoter = document.createComponentDefinition("BBa_R0040", types);
ComponentDefinition LacI_repressor = document.createComponentDefinition("BBa_C0012", types);
ComponentDefinition pIKELeftCassette = document.createComponentDefinition("pIKELeftCassette", types);
Sequence seq_187 = document.createSequence("partseq_187", "tccctatcagtgatagagattgacatccctatcagtgatagagatactgagcac", Sequence.IUPAC_DNA);
String element2 = "atggtgaatgtgaaaccagtaacgttatacgatgtcgcagagtatgccggtgtc" + "tcttatcagaccgtttcccgcgtggtgaaccaggccagccacgtttctgcgaaaacgcggga" + "aaaagtggaagcggcgatggcggagctgaattacattcccaaccgcgtggcacaacaactgg" + "cgggcaaacagtcgttgctgattggcgttgccacctccagtctggccctgcacgcgccgtcg" + "caaattgtcgcggcgattaaatctcgcgccgatcaactgggtgccagcgtggtggtgtcgat" + "ggtagaacgaagcggcgtcgaagcctgtaaagcggcggtgcacaatcttctcgcgcaacgcg" + "tcagtgggctgatcattaactatccgctggatgaccaggatgccattgctgtggaagctgcc" + "tgcactaatgttccggcgttatttcttgatgtctctgaccagacacccatcaacagtattat" + "tttctcccatgaagacggtacgcgactgggcgtggagcatctggtcgcattgggtcaccagc" + "aaatcgcgctgttagcgggcccattaagttctgtctcggcgcgtctgcgtctggctggctgg" + "cataaatatctcactcgcaatcaaattcagccgatagcggaacgggaaggcgactggagtgc" + "catgtccggttttcaacaaaccatgcaaatgctgaatgagggcatcgttcccactgcgatgc" + "tggttgccaacgatcagatggcgctgggcgcaatgcgcgccattaccgagtccgggctgcgc" + "gttggtgcggatatctcggtagtgggatacgacgataccgaagacagctcatgttatatccc" + "gccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgc" + "tgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaa" + "agaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcatt" + "aatgcagctggcacgacaggtttcccgactggaaagcgggcaggctgcaaacgacgaaaact" + "acgctttagtagcttaataa";
Sequence seq_153 = document.createSequence("partseq_153", element2, Sequence.IUPAC_DNA);
// Setting and editing optional fields
TetR_promoter.setName("p(tetR)");
LacI_repressor.setName("lacI");
TetR_promoter.setDescription("TetR repressible promoter");
LacI_repressor.setDescription("lacI repressor from E. coli (+LVA)");
if (TetR_promoter.isSetName()) {
TetR_promoter.unsetName();
}
TetR_promoter.setName("p(tetR)");
TetR_promoter.addRole(SequenceOntology.PROMOTER);
LacI_repressor.addRole(SequenceOntology.CDS);
URI TetR_promoter_role2 = URI.create("http://identifiers.org/so/SO:0000613");
TetR_promoter.addRole(TetR_promoter_role2);
if (TetR_promoter.containsRole(TetR_promoter_role2)) {
TetR_promoter.removeRole(TetR_promoter_role2);
}
TetR_promoter.clearRoles();
if (!TetR_promoter.getRoles().isEmpty()) {
System.out.println("TetR_promoter set is not empty");
}
TetR_promoter.setRoles(new HashSet<URI>(Arrays.asList(SequenceOntology.PROMOTER)));
// Creating and editing references
TetR_promoter.addSequence(seq_187);
LacI_repressor.addSequence(seq_153);
pIKELeftCassette.addSequence(seq_187);
pIKELeftCassette.clearSequences();
// Adding the sequence below causes an exception because it cannot be found
// pIKELeftCassette.addSequence(URI.create("http://partsregistry.org/seq/partseq_154"));
// Creating Annotations
TetR_promoter.createAnnotation(new QName(prURI, "experience", prPrefix), URI.create("http://parts.igem.org/Part:BBa_R0040"));
// Creating Generic TopLevel Object
GenericTopLevel datasheet = document.createGenericTopLevel("datasheet", "1.0", new QName(myersLabURI, "datasheet", myersLabPrefix));
datasheet.setName("Datasheet for Custom Parameters");
datasheet.createAnnotation(new QName(myersLabURI, "characterizationData", myersLabPrefix), URI.create(myersLabURI + "/measurement/Part:BBa_R0040"));
datasheet.createAnnotation(new QName(myersLabURI, "transcriptionRate", myersLabPrefix), "0.75");
TetR_promoter.createAnnotation(new QName(myersLabURI, "datasheet", myersLabPrefix), datasheet.getIdentity());
// Creating and editing Child Objects
// For pIKELeftCassette, create sequence constraint that says BBa_R0040 precedes BBa_C0012.
// Note that with CreateDefaults that components get created automatically.
// The position of the subject Component MUST precede that of the object Component.
pIKELeftCassette.createSequenceConstraint("pIKELeftCassette_sc", RestrictionType.PRECEDES, TetR_promoter.getDisplayId(), LacI_repressor.getDisplayId());
if (pIKELeftCassette.getComponent("BBa_R0040") == null) {
System.out.println("TetR_promoter component is missing");
}
if (pIKELeftCassette.getComponent("BBa_C0012") == null) {
System.out.println("LacI_repressor component is missing");
}
// Removing the subject component below causes an exception.
// pIKELeftCassette.removeComponent(pIKELeftCassette.getComponent("BBa_R0040"));
// Copying objects
ComponentDefinition TetR_promoter_copy = (ComponentDefinition) document.createCopy(TetR_promoter, "BBa_K137046");
Sequence seq = document.createSequence("seq_K137046", "gtgctcagtatctctatcactgatagggatgtcaatctctatcactgatagggactctagtatat" + "aaacgcagaaaggcccacccgaaggtgagccagtgtgactctagtagagagcgttcaccgaca" + "aacaacagataaaacgaaaggc", Sequence.IUPAC_DNA);
TetR_promoter_copy.addSequence(seq);
SBOLWriter.write(document, "GettingStartedExample.rdf");
writeThenRead(document);
}
use of org.sbolstandard.core2.GenericTopLevel in project libSBOLj by SynBioDex.
the class SBOLReader method parseActivity.
@SuppressWarnings("unchecked")
private static Activity parseActivity(SBOLDocument SBOLDoc, IdentifiableDocument<QName> topLevel, Map<URI, NestedDocument<QName>> nested) throws SBOLValidationException {
String displayId = null;
String name = null;
String description = null;
URI persistentIdentity = null;
String version = null;
Set<URI> wasDerivedFroms = new HashSet<>();
Set<URI> wasGeneratedBys = new HashSet<>();
Set<URI> attachments = new HashSet<>();
DateTime startedAtTime = null;
DateTime endedAtTime = null;
Set<URI> wasInformedBys = new HashSet<>();
Set<Association> qualifiedAssociations = new HashSet<>();
Set<Usage> qualifiedUsages = new HashSet<>();
List<Annotation> annotations = new ArrayList<>();
for (NamedProperty<QName> namedProperty : topLevel.getProperties()) {
if (namedProperty.getName().equals(Sbol2Terms.Identified.persistentIdentity)) {
if (!(namedProperty.getValue() instanceof Literal) || persistentIdentity != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI))) {
throw new SBOLValidationException("sbol-10203", topLevel.getIdentity());
}
persistentIdentity = URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString());
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.version)) {
if (!(namedProperty.getValue() instanceof Literal) || version != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10206", topLevel.getIdentity());
}
version = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.displayId)) {
if (!(namedProperty.getValue() instanceof Literal) || displayId != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10204", topLevel.getIdentity());
}
displayId = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.title)) {
if (!(namedProperty.getValue() instanceof Literal) || name != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10212", topLevel.getIdentity());
}
name = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.description)) {
if (!(namedProperty.getValue() instanceof Literal) || description != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10213", topLevel.getIdentity());
}
description = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.wasDerivedFrom)) {
if (!(namedProperty.getValue() instanceof Literal) || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI))) {
throw new SBOLValidationException("sbol-10208", topLevel.getIdentity());
}
wasDerivedFroms.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.wasGeneratedBy)) {
if (!(namedProperty.getValue() instanceof Literal) || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI))) {
throw new SBOLValidationException("sbol-10221", topLevel.getIdentity());
}
wasGeneratedBys.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getName().equals(Sbol2Terms.TopLevel.hasAttachment)) {
if (namedProperty.getValue() instanceof Literal) {
if (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI)) {
throw new SBOLValidationException("sbol-XXXXX", topLevel.getIdentity());
}
attachments.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getValue() instanceof IdentifiableDocument) {
if (((IdentifiableDocument<QName>) namedProperty).getType().equals(Sbol2Terms.Attachment.Attachment)) {
Attachment attachment = parseAttachment(SBOLDoc, (IdentifiableDocument<QName>) namedProperty.getValue());
attachments.add(attachment.getIdentity());
} else {
throw new SBOLValidationException("sbol-XXXXX", topLevel.getIdentity());
}
} else {
throw new SBOLValidationException("sbol-XXXXX", topLevel.getIdentity());
}
} else if (namedProperty.getName().equals(Sbol2Terms.Activity.startedAtTime)) {
if (!(namedProperty.getValue() instanceof Literal) || startedAtTime != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-12402", topLevel.getIdentity());
}
DateTimeFormatter fmt = ISODateTimeFormat.dateTime();
try {
startedAtTime = fmt.parseDateTime(((Literal<QName>) namedProperty.getValue()).getValue().toString());
} catch (IllegalArgumentException e) {
throw new SBOLValidationException("sbol-12402", topLevel.getIdentity());
}
} else if (namedProperty.getName().equals(Sbol2Terms.Activity.endedAtTime)) {
if (!(namedProperty.getValue() instanceof Literal) || endedAtTime != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-12403", topLevel.getIdentity());
}
DateTimeFormatter fmt = ISODateTimeFormat.dateTime();
try {
endedAtTime = fmt.parseDateTime(((Literal<QName>) namedProperty.getValue()).getValue().toString());
} catch (IllegalArgumentException e) {
throw new SBOLValidationException("sbol-12403", topLevel.getIdentity());
}
} else if (namedProperty.getName().equals(Sbol2Terms.Activity.wasInformedBy)) {
if (namedProperty.getValue() instanceof Literal) {
if (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI)) {
throw new SBOLValidationException("sbol-12406", topLevel.getIdentity());
}
wasInformedBys.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getValue() instanceof IdentifiableDocument) {
if (((IdentifiableDocument<QName>) namedProperty).getType().equals(Sbol2Terms.Activity.Activity)) {
Activity activity = parseActivity(SBOLDoc, (IdentifiableDocument<QName>) namedProperty.getValue(), nested);
wasInformedBys.add(activity.getIdentity());
} else {
throw new SBOLValidationException("sbol-12406", topLevel.getIdentity());
}
} else {
throw new SBOLValidationException("sbol-12406", topLevel.getIdentity());
}
} else if (namedProperty.getName().equals(Sbol2Terms.Activity.qualifiedAssociation)) {
if (namedProperty.getValue() instanceof NestedDocument) {
NestedDocument<QName> nestedDocument = ((NestedDocument<QName>) namedProperty.getValue());
if (nestedDocument.getType() == null || !nestedDocument.getType().equals(Sbol2Terms.Association.Association)) {
throw new SBOLValidationException("sbol-12404", topLevel.getIdentity());
}
qualifiedAssociations.add(parseAssociation(SBOLDoc, ((NestedDocument<QName>) namedProperty.getValue()), nested));
} else {
URI uri = (URI) ((Literal<QName>) namedProperty.getValue()).getValue();
NestedDocument<QName> nestedDocument = nested.get(uri);
if (nestedDocument == null || nestedDocument.getType() == null || !nestedDocument.getType().equals(Sbol2Terms.Association.Association)) {
throw new SBOLValidationException("sbol-12404", topLevel.getIdentity());
}
qualifiedAssociations.add(parseAssociation(SBOLDoc, nestedDocument, nested));
}
} else if (namedProperty.getName().equals(Sbol2Terms.Activity.qualifiedUsage)) {
if (namedProperty.getValue() instanceof NestedDocument) {
NestedDocument<QName> nestedDocument = ((NestedDocument<QName>) namedProperty.getValue());
if (nestedDocument.getType() == null || !nestedDocument.getType().equals(Sbol2Terms.Usage.Usage)) {
throw new SBOLValidationException("sbol-12405", topLevel.getIdentity());
}
qualifiedUsages.add(parseUsage(SBOLDoc, ((NestedDocument<QName>) namedProperty.getValue()), nested));
} else {
URI uri = (URI) ((Literal<QName>) namedProperty.getValue()).getValue();
NestedDocument<QName> nestedDocument = nested.get(uri);
if (nestedDocument == null || nestedDocument.getType() == null || !nestedDocument.getType().equals(Sbol2Terms.Usage.Usage)) {
throw new SBOLValidationException("sbol-12405", topLevel.getIdentity());
}
qualifiedUsages.add(parseUsage(SBOLDoc, nestedDocument, nested));
}
} else {
annotations.add(new Annotation(namedProperty));
}
}
// GenericTopLevel t = SBOLDoc.createGenericTopLevel(topLevel.getIdentity(), topLevel.getType());
Activity t = new Activity(topLevel.getIdentity());
if (persistentIdentity != null)
t.setPersistentIdentity(persistentIdentity);
if (version != null)
t.setVersion(version);
if (displayId != null)
t.setDisplayId(displayId);
if (name != null)
t.setName(name);
if (description != null)
t.setDescription(description);
t.setWasDerivedFroms(wasDerivedFroms);
t.setWasGeneratedBys(wasGeneratedBys);
if (!annotations.isEmpty())
t.setAnnotations(annotations);
if (startedAtTime != null)
t.setStartedAtTime(startedAtTime);
if (endedAtTime != null)
t.setEndedAtTime(endedAtTime);
if (!qualifiedAssociations.isEmpty())
t.setAssociations(qualifiedAssociations);
if (!qualifiedUsages.isEmpty())
t.setUsages(qualifiedUsages);
if (!wasInformedBys.isEmpty())
t.setWasInformedBys(wasInformedBys);
if (!attachments.isEmpty())
t.setAttachments(attachments);
Activity oldA = SBOLDoc.getActivity(topLevel.getIdentity());
if (oldA == null) {
SBOLDoc.addActivity(t);
} else {
if (!t.equals(oldA)) {
throw new SBOLValidationException("sbol-10202", t);
}
}
return t;
}
use of org.sbolstandard.core2.GenericTopLevel in project libSBOLj by SynBioDex.
the class SBOLDocument method updateReferences.
// TODO: need to update persistentIdentities too
private void updateReferences(HashMap<URI, URI> uriMap) throws SBOLValidationException {
for (TopLevel topLevel : getTopLevels()) {
for (URI wasDerivedFrom : topLevel.getWasDerivedFroms()) {
if (uriMap.get(wasDerivedFrom) != null) {
topLevel.removeWasDerivedFrom(wasDerivedFrom);
topLevel.addWasDerivedFrom(uriMap.get(wasDerivedFrom));
}
}
for (URI wasGeneratedBy : topLevel.getWasGeneratedBys()) {
if (uriMap.get(wasGeneratedBy) != null) {
topLevel.removeWasGeneratedBy(wasGeneratedBy);
topLevel.addWasGeneratedBy(uriMap.get(wasGeneratedBy));
}
}
for (URI attachmentURI : topLevel.getAttachmentURIs()) {
if (uriMap.get(attachmentURI) != null) {
topLevel.removeAttachment(attachmentURI);
topLevel.addAttachment(uriMap.get(attachmentURI));
}
}
}
for (Collection collection : getCollections()) {
for (URI memberURI : collection.getMemberURIs()) {
if (uriMap.get(memberURI) != null) {
collection.removeMember(memberURI);
collection.addMember(uriMap.get(memberURI));
}
}
updateReferences(collection, uriMap);
}
for (ComponentDefinition componentDefinition : getComponentDefinitions()) {
updateReferences(componentDefinition, uriMap);
for (Component component : componentDefinition.getComponents()) {
if (uriMap.get(component.getDefinitionURI()) != null) {
component.setDefinition(uriMap.get(component.getDefinitionURI()));
for (MapsTo mapsTo : component.getMapsTos()) {
ComponentDefinition cd = getComponentDefinition(component.getDefinitionURI());
if (cd != null) {
String displayId = URIcompliance.extractDisplayId(mapsTo.getRemoteURI());
URI newURI = URIcompliance.createCompliantURI(cd.getPersistentIdentity().toString(), displayId, cd.getVersion());
mapsTo.setRemote(newURI);
}
}
}
updateReferences(component, uriMap);
for (MapsTo mapsTo : component.getMapsTos()) {
updateReferences(mapsTo, uriMap);
}
}
for (SequenceAnnotation sa : componentDefinition.getSequenceAnnotations()) {
for (Location loc : sa.getLocations()) {
updateReferences(loc, uriMap);
}
updateReferences(sa, uriMap);
}
for (SequenceConstraint sc : componentDefinition.getSequenceConstraints()) {
updateReferences(sc, uriMap);
}
for (URI sequenceURI : componentDefinition.getSequenceURIs()) {
if (uriMap.get(sequenceURI) != null) {
componentDefinition.removeSequence(sequenceURI);
componentDefinition.addSequence(uriMap.get(sequenceURI));
}
}
}
for (ModuleDefinition moduleDefinition : getModuleDefinitions()) {
updateReferences(moduleDefinition, uriMap);
for (FunctionalComponent functionalComponent : moduleDefinition.getFunctionalComponents()) {
if (uriMap.get(functionalComponent.getDefinitionURI()) != null) {
functionalComponent.setDefinition(uriMap.get(functionalComponent.getDefinitionURI()));
for (MapsTo mapsTo : functionalComponent.getMapsTos()) {
ComponentDefinition cd = getComponentDefinition(functionalComponent.getDefinitionURI());
if (cd != null) {
String displayId = URIcompliance.extractDisplayId(mapsTo.getRemoteURI());
URI newURI = URIcompliance.createCompliantURI(cd.getPersistentIdentity().toString(), displayId, cd.getVersion());
mapsTo.setRemote(newURI);
}
}
}
updateReferences(functionalComponent, uriMap);
for (MapsTo mapsTo : functionalComponent.getMapsTos()) {
updateReferences(mapsTo, uriMap);
}
}
for (Module module : moduleDefinition.getModules()) {
if (uriMap.get(module.getDefinitionURI()) != null) {
module.setDefinition(uriMap.get(module.getDefinitionURI()));
for (MapsTo mapsTo : module.getMapsTos()) {
ModuleDefinition md = getModuleDefinition(module.getDefinitionURI());
if (md != null) {
String displayId = URIcompliance.extractDisplayId(mapsTo.getRemoteURI());
URI newURI = URIcompliance.createCompliantURI(md.getPersistentIdentity().toString(), displayId, md.getVersion());
mapsTo.setRemote(newURI);
}
}
}
updateReferences(module, uriMap);
for (MapsTo mapsTo : module.getMapsTos()) {
updateReferences(mapsTo, uriMap);
}
}
for (Interaction interaction : moduleDefinition.getInteractions()) {
updateReferences(interaction, uriMap);
for (Participation participation : interaction.getParticipations()) {
updateReferences(participation, uriMap);
}
}
for (URI modelURI : moduleDefinition.getModelURIs()) {
if (uriMap.get(modelURI) != null) {
moduleDefinition.removeModel(modelURI);
moduleDefinition.addModel(uriMap.get(modelURI));
}
}
}
for (Model model : getModels()) {
updateReferences(model, uriMap);
}
for (Sequence sequence : getSequences()) {
updateReferences(sequence, uriMap);
}
for (Attachment attachment : getAttachments()) {
updateReferences(attachment, uriMap);
}
for (Implementation implementation : getImplementations()) {
if (implementation.isSetBuilt()) {
URI built = implementation.getBuiltURI();
if (uriMap.get(built) != null) {
implementation.setBuilt(uriMap.get(built));
}
}
updateReferences(implementation, uriMap);
}
for (GenericTopLevel genericTopLevel : getGenericTopLevels()) {
updateReferences(genericTopLevel, uriMap);
}
for (CombinatorialDerivation combinatorialDerivation : getCombinatorialDerivations()) {
updateReferences(combinatorialDerivation, uriMap);
if (uriMap.get(combinatorialDerivation.getTemplateURI()) != null) {
combinatorialDerivation.setTemplate(uriMap.get(combinatorialDerivation.getTemplateURI()));
ComponentDefinition cd = getComponentDefinition(combinatorialDerivation.getTemplateURI());
if (cd != null) {
for (VariableComponent variableComponent : combinatorialDerivation.getVariableComponents()) {
String displayId = URIcompliance.extractDisplayId(variableComponent.getVariableURI());
URI newURI = URIcompliance.createCompliantURI(cd.getPersistentIdentity().toString(), displayId, cd.getVersion());
variableComponent.setVariable(newURI);
}
}
}
for (VariableComponent variableComponent : combinatorialDerivation.getVariableComponents()) {
updateReferences(variableComponent, uriMap);
}
}
for (Activity activity : getActivities()) {
updateReferences(activity, uriMap);
for (Association association : activity.getAssociations()) {
if (uriMap.get(association.getAgentURI()) != null) {
association.setAgent(uriMap.get(association.getAgentURI()));
}
if (uriMap.get(association.getPlanURI()) != null) {
association.setPlan(uriMap.get(association.getPlanURI()));
}
updateReferences(association, uriMap);
}
for (Usage usage : activity.getUsages()) {
if (uriMap.get(usage.getEntityURI()) != null) {
usage.setEntity(uriMap.get(usage.getEntityURI()));
}
updateReferences(usage, uriMap);
}
}
for (Agent agent : getAgents()) {
updateReferences(agent, uriMap);
}
for (Plan plan : getPlans()) {
updateReferences(plan, uriMap);
}
}
use of org.sbolstandard.core2.GenericTopLevel in project libSBOLj by SynBioDex.
the class SBOLReader method parseGenericTopLevel.
/**
* @param SBOLDoc
* @param topLevel
* @return
* @throws SBOLValidationException if either of the following conditions is satisfied:
* <ul>
* <li>any of the following SBOL validation rules was violated:
* 10202, 10203, 10204, 10206, 10208, 10212, 10213, 12102; or</li>
* <li>an SBOL validation rule violation occurred in the following constructor or methods:
* <ul>
* <li>{@link GenericTopLevel#GenericTopLevel(URI, QName)}, </li>
* <li>{@link GenericTopLevel#setDisplayId(String)}, </li>
* <li>{@link GenericTopLevel#setVersion(String)}, </li>
* <li>{@link GenericTopLevel#setWasDerivedFrom(URI)}, </li>
* <li>{@link Identified#setAnnotations(List)}, or</li>
* <li>{@link SBOLDocument#addGenericTopLevel(GenericTopLevel)}.</li>
* </ul>
* </li>
* </ul>
*/
@SuppressWarnings("unchecked")
private static GenericTopLevel parseGenericTopLevel(SBOLDocument SBOLDoc, IdentifiableDocument<QName> topLevel) throws SBOLValidationException {
// URIcompliance.extractDisplayId(topLevel.getIdentity());
String displayId = null;
String name = null;
String description = null;
// URI.create(URIcompliance.extractPersistentId(topLevel.getIdentity()));
URI persistentIdentity = null;
String version = null;
Set<URI> wasDerivedFroms = new HashSet<>();
Set<URI> wasGeneratedBys = new HashSet<>();
Set<URI> attachments = new HashSet<>();
QName type = topLevel.getType();
List<Annotation> annotations = new ArrayList<>();
for (NamedProperty<QName> namedProperty : topLevel.getProperties()) {
if (namedProperty.getName().equals(Sbol2Terms.Description.type)) {
String typeStr = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
String nameSpace = URIcompliance.extractNamespace(URI.create(typeStr));
String localPart = URIcompliance.extractDisplayId(URI.create(typeStr));
String prefix = null;
if (nameSpace == null) {
if (typeStr.lastIndexOf('/') > typeStr.lastIndexOf('#')) {
if (typeStr.lastIndexOf('/') > typeStr.lastIndexOf(':')) {
nameSpace = typeStr.substring(0, typeStr.lastIndexOf('/') + 1);
localPart = typeStr.substring(typeStr.lastIndexOf('/') + 1);
} else {
nameSpace = typeStr.substring(0, typeStr.lastIndexOf(':') + 1);
localPart = typeStr.substring(typeStr.lastIndexOf(':') + 1);
}
} else if (typeStr.lastIndexOf('#') > typeStr.lastIndexOf(':')) {
nameSpace = typeStr.substring(0, typeStr.lastIndexOf('#') + 1);
localPart = typeStr.substring(typeStr.lastIndexOf('#') + 1);
} else {
nameSpace = typeStr.substring(0, typeStr.lastIndexOf(':') + 1);
localPart = typeStr.substring(typeStr.lastIndexOf(':') + 1);
}
prefix = SBOLDoc.getNamespacePrefix(URI.create(nameSpace));
if (prefix == null) {
prefix = "ns0";
int prefixCnt = 0;
while (SBOLDoc.getNamespace(prefix) != null) {
prefixCnt++;
prefix = "ns" + prefixCnt;
}
SBOLDoc.addNamespace(new QName(nameSpace, localPart, prefix));
}
} else {
prefix = SBOLDoc.getNamespacePrefix(URI.create(nameSpace));
}
if (!nameSpace.equals(Sbol2Terms.sbol2.getNamespaceURI()))
type = new QName(nameSpace, localPart, prefix);
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.persistentIdentity)) {
if (!(namedProperty.getValue() instanceof Literal) || persistentIdentity != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI))) {
throw new SBOLValidationException("sbol-10203", topLevel.getIdentity());
}
persistentIdentity = URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString());
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.version)) {
if (!(namedProperty.getValue() instanceof Literal) || version != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10206", topLevel.getIdentity());
}
version = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.displayId)) {
if (!(namedProperty.getValue() instanceof Literal) || displayId != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10204", topLevel.getIdentity());
}
displayId = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.title)) {
if (!(namedProperty.getValue() instanceof Literal) || name != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10212", topLevel.getIdentity());
}
name = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.description)) {
if (!(namedProperty.getValue() instanceof Literal) || description != null || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof String))) {
throw new SBOLValidationException("sbol-10213", topLevel.getIdentity());
}
description = ((Literal<QName>) namedProperty.getValue()).getValue().toString();
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.wasDerivedFrom)) {
if (!(namedProperty.getValue() instanceof Literal) || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI))) {
throw new SBOLValidationException("sbol-10208", topLevel.getIdentity());
}
wasDerivedFroms.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getName().equals(Sbol2Terms.Identified.wasGeneratedBy)) {
if (!(namedProperty.getValue() instanceof Literal) || (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI))) {
throw new SBOLValidationException("sbol-10221", topLevel.getIdentity());
}
wasGeneratedBys.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getName().equals(Sbol2Terms.TopLevel.hasAttachment)) {
if (namedProperty.getValue() instanceof Literal) {
if (!(((Literal<QName>) namedProperty.getValue()).getValue() instanceof URI)) {
throw new SBOLValidationException("sbol-XXXXX", topLevel.getIdentity());
}
attachments.add(URI.create(((Literal<QName>) namedProperty.getValue()).getValue().toString()));
} else if (namedProperty.getValue() instanceof IdentifiableDocument) {
if (((IdentifiableDocument<QName>) namedProperty).getType().equals(Sbol2Terms.Attachment.Attachment)) {
Attachment attachment = parseAttachment(SBOLDoc, (IdentifiableDocument<QName>) namedProperty.getValue());
attachments.add(attachment.getIdentity());
} else {
throw new SBOLValidationException("sbol-XXXXX", topLevel.getIdentity());
}
} else {
throw new SBOLValidationException("sbol-XXXXX", topLevel.getIdentity());
}
} else {
annotations.add(new Annotation(namedProperty));
}
}
// GenericTopLevel t = SBOLDoc.createGenericTopLevel(topLevel.getIdentity(), topLevel.getType());
GenericTopLevel t = new GenericTopLevel(topLevel.getIdentity(), type);
if (persistentIdentity != null)
t.setPersistentIdentity(persistentIdentity);
if (version != null)
t.setVersion(version);
if (displayId != null)
t.setDisplayId(displayId);
if (name != null)
t.setName(name);
if (description != null)
t.setDescription(description);
t.setWasDerivedFroms(wasDerivedFroms);
t.setWasGeneratedBys(wasGeneratedBys);
t.setAttachments(attachments);
if (!annotations.isEmpty())
t.setAnnotations(annotations);
GenericTopLevel oldG = SBOLDoc.getGenericTopLevel(topLevel.getIdentity());
if (oldG == null) {
SBOLDoc.addGenericTopLevel(t);
} else {
if (!t.equals(oldG)) {
throw new SBOLValidationException("sbol-10202", t);
}
}
return t;
}
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