Examples with HomogeneousBranchModel dr.evomodel.branchmodel.HomogeneousBranchModel used on opensource projects

Example 6 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class TreeDataLikelihoodParser method parseXMLObject.

public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    boolean useAmbiguities = xo.getAttribute(USE_AMBIGUITIES, false);
    // TreeDataLikelihood doesn't currently support Instances defined from the command line
    //        int instanceCount = xo.getAttribute(INSTANCE_COUNT, 1);
    //        if (instanceCount < 1) {
    //            instanceCount = 1;
    //        }
    //
    //        String ic = System.getProperty(BEAGLE_INSTANCE_COUNT);
    //        if (ic != null && ic.length() > 0) {
    //            instanceCount = Integer.parseInt(ic);
    //        }
    List<PatternList> patternLists = new ArrayList<PatternList>();
    List<SiteRateModel> siteRateModels = new ArrayList<SiteRateModel>();
    List<BranchModel> branchModels = new ArrayList<BranchModel>();
    boolean hasSinglePartition = false;
    PatternList patternList = (PatternList) xo.getChild(PatternList.class);
    if (patternList != null) {
        hasSinglePartition = true;
        patternLists.add(patternList);
        GammaSiteRateModel siteRateModel = (GammaSiteRateModel) xo.getChild(GammaSiteRateModel.class);
        siteRateModels.add(siteRateModel);
        FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
        BranchModel branchModel = (BranchModel) xo.getChild(BranchModel.class);
        if (branchModel == null) {
            SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
            if (substitutionModel == null) {
                substitutionModel = siteRateModel.getSubstitutionModel();
            }
            if (substitutionModel == null) {
                throw new XMLParseException("No substitution model available for partition in DataTreeLikelihood: " + xo.getId());
            }
            branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
        }
        branchModels.add(branchModel);
    }
    int k = 0;
    for (int i = 0; i < xo.getChildCount(); i++) {
        if (xo.getChildName(i).equals(PARTITION)) {
            if (hasSinglePartition) {
                throw new XMLParseException("Either a single set of patterns should be given or multiple 'partitions' elements within DataTreeLikelihood: " + xo.getId());
            }
            k += 1;
            XMLObject cxo = (XMLObject) xo.getChild(i);
            patternList = (PatternList) cxo.getChild(PatternList.class);
            patternLists.add(patternList);
            GammaSiteRateModel siteRateModel = (GammaSiteRateModel) cxo.getChild(GammaSiteRateModel.class);
            siteRateModels.add(siteRateModel);
            FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
            BranchModel branchModel = (BranchModel) cxo.getChild(BranchModel.class);
            if (branchModel == null) {
                SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
                if (substitutionModel == null) {
                    substitutionModel = siteRateModel.getSubstitutionModel();
                }
                if (substitutionModel == null) {
                    throw new XMLParseException("No substitution model available for partition " + k + " in DataTreeLikelihood: " + xo.getId());
                }
                branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
            }
            branchModels.add(branchModel);
        }
    }
    if (patternLists.size() == 0) {
        throw new XMLParseException("Either a single set of patterns should be given or multiple 'partitions' elements within DataTreeLikelihood: " + xo.getId());
    }
    TreeModel treeModel = (TreeModel) xo.getChild(TreeModel.class);
    BranchRateModel branchRateModel = (BranchRateModel) xo.getChild(BranchRateModel.class);
    if (branchRateModel == null) {
        branchRateModel = new DefaultBranchRateModel();
    }
    TipStatesModel tipStatesModel = (TipStatesModel) xo.getChild(TipStatesModel.class);
    PartialsRescalingScheme scalingScheme = PartialsRescalingScheme.DEFAULT;
    boolean delayScaling = true;
    if (xo.hasAttribute(SCALING_SCHEME)) {
        scalingScheme = PartialsRescalingScheme.parseFromString(xo.getStringAttribute(SCALING_SCHEME));
        if (scalingScheme == null)
            throw new XMLParseException("Unknown scaling scheme '" + xo.getStringAttribute(SCALING_SCHEME) + "' in " + "BeagleDataLikelihood object '" + xo.getId());
    }
    if (xo.hasAttribute(DELAY_SCALING)) {
        delayScaling = xo.getBooleanAttribute(DELAY_SCALING);
    }
    if (tipStatesModel != null) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with a TipStateModel (i.e., a sequence error model).");
    }
    return createTreeDataLikelihood(patternLists, branchModels, siteRateModels, treeModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling);
}

Example 7 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class BalancedBeagleTreeLikelihoodParser method parseXMLObject.

public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    boolean useAmbiguities = xo.getAttribute(BeagleTreeLikelihoodParser.USE_AMBIGUITIES, false);
    /*int instanceCount = xo.getAttribute(INSTANCE_COUNT, 1);
        if (instanceCount < 1) {
            instanceCount = 1;
        }

        String ic = System.getProperty(BEAGLE_INSTANCE_COUNT);
        if (ic != null && ic.length() > 0) {
            instanceCount = Integer.parseInt(ic);
        }*/
    PatternList patternList = (PatternList) xo.getChild(PatternList.class);
    TreeModel treeModel = (TreeModel) xo.getChild(TreeModel.class);
    GammaSiteRateModel siteRateModel = (GammaSiteRateModel) xo.getChild(GammaSiteRateModel.class);
    FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
    BranchModel branchModel = (BranchModel) xo.getChild(BranchModel.class);
    if (branchModel == null) {
        SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
        if (substitutionModel == null) {
            substitutionModel = siteRateModel.getSubstitutionModel();
        }
        if (substitutionModel == null) {
            throw new XMLParseException("No substitution model available for TreeLikelihood: " + xo.getId());
        }
        branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
    }
    BranchRateModel branchRateModel = (BranchRateModel) xo.getChild(BranchRateModel.class);
    TipStatesModel tipStatesModel = (TipStatesModel) xo.getChild(TipStatesModel.class);
    //        if (xo.getChild(TipStatesModel.class) != null) {
    //            throw new XMLParseException("Sequence Error Models are not supported under BEAGLE yet. Please use Native BEAST Likelihood.");
    //        }
    PartialsRescalingScheme scalingScheme = PartialsRescalingScheme.DEFAULT;
    if (xo.hasAttribute(BeagleTreeLikelihoodParser.SCALING_SCHEME)) {
        //            scalingScheme = PartialsRescalingScheme.parseFromString(xo.getStringAttribute(BeagleTreeLikelihoodParser.SCALING_SCHEME));
        if (scalingScheme == null)
            throw new XMLParseException("Unknown scaling scheme '" + xo.getStringAttribute(BeagleTreeLikelihoodParser.SCALING_SCHEME) + "' in " + "OldBeagleTreeLikelihood object '" + xo.getId());
    }
    boolean delayScaling = true;
    Map<Set<String>, Parameter> partialsRestrictions = null;
    if (xo.hasChildNamed(PARTIALS_RESTRICTION)) {
        XMLObject cxo = xo.getChild(PARTIALS_RESTRICTION);
        TaxonList taxonList = (TaxonList) cxo.getChild(TaxonList.class);
        //            Parameter parameter = (Parameter) cxo.getChild(Parameter.class);
        try {
            TreeUtils.getLeavesForTaxa(treeModel, taxonList);
        } catch (TreeUtils.MissingTaxonException e) {
            throw new XMLParseException("Unable to parse taxon list: " + e.getMessage());
        }
        throw new XMLParseException("Restricting internal nodes is not yet implemented.  Contact Marc");
    }
    /*if (instanceCount == 1 || patternList.getPatternCount() < instanceCount) {
            return createTreeLikelihood(
                    patternList,
                    treeModel,
                    branchModel,
                    siteRateModel,
                    branchRateModel,
                    tipStatesModel,
                    useAmbiguities,
                    scalingScheme,
                    partialsRestrictions,
                    xo
            );
        }*/
    //first run a test for instanceCount == 1
    System.err.println("\nTesting instanceCount == 1");
    Likelihood baseLikelihood = createTreeLikelihood(patternList, treeModel, branchModel, siteRateModel, branchRateModel, tipStatesModel, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
    double start = System.nanoTime();
    for (int i = 0; i < TEST_RUNS; i++) {
        baseLikelihood.makeDirty();
        baseLikelihood.getLogLikelihood();
    }
    double end = System.nanoTime();
    double baseResult = end - start;
    System.err.println("Evaluation took: " + baseResult);
    if (!(patternList instanceof SitePatterns)) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with BEAUti-selected codon partitioning.");
    }
    if (tipStatesModel != null) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with a TipStateModel (i.e., a sequence error model).");
    }
    //List<Likelihood> likelihoods = new ArrayList<Likelihood>();
    List<Likelihood> likelihoods = null;
    CompoundLikelihood compound = null;
    int instanceCount = 2;
    boolean optimal = false;
    while (optimal == false) {
        System.err.println("\nCreating instanceCount == " + instanceCount);
        likelihoods = new ArrayList<Likelihood>();
        for (int i = 0; i < instanceCount; i++) {
            Patterns subPatterns = new Patterns((SitePatterns) patternList, 0, 0, 1, i, instanceCount);
            AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(subPatterns, treeModel, branchModel, siteRateModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
            treeLikelihood.setId(xo.getId() + "_" + instanceCount);
            likelihoods.add(treeLikelihood);
        }
        //construct compoundLikelihood
        compound = new CompoundLikelihood(instanceCount, likelihoods);
        //test timings 
        System.err.println("\nTesting instanceCount == " + instanceCount);
        start = System.nanoTime();
        for (int i = 0; i < TEST_RUNS; i++) {
            compound.makeDirty();
            compound.getLogLikelihood();
        }
        end = System.nanoTime();
        double newResult = end - start;
        System.err.println("Evaluation took: " + newResult);
        if (baseResult / newResult > TEST_CUTOFF) {
            instanceCount++;
            baseResult = newResult;
        } else {
            optimal = true;
            instanceCount--;
            System.err.println("\nCreating final BeagleTreeLikelihood with instanceCount: " + instanceCount);
            likelihoods = new ArrayList<Likelihood>();
            for (int i = 0; i < instanceCount; i++) {
                Patterns subPatterns = new Patterns((SitePatterns) patternList, 0, 0, 1, i, instanceCount);
                AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(subPatterns, treeModel, branchModel, siteRateModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
                treeLikelihood.setId(xo.getId() + "_" + instanceCount);
                likelihoods.add(treeLikelihood);
            }
            //construct compoundLikelihood
            compound = new CompoundLikelihood(instanceCount, likelihoods);
        }
    }
    return compound;
/*for (int i = 0; i < instanceCount; i++) {

            Patterns subPatterns = new Patterns((SitePatterns)patternList, 0, 0, 1, i, instanceCount);

            AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(
                    subPatterns,
                    treeModel,
                    branchModel,
                    siteRateModel,
                    branchRateModel,
                    null,
                    useAmbiguities,
                    scalingScheme,
                    partialsRestrictions,
                    xo);
            treeLikelihood.setId(xo.getId() + "_" + instanceCount);
            likelihoods.add(treeLikelihood);
        }

        return new CompoundLikelihood(likelihoods);*/
}

Example 8 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class BeagleTreeLikelihoodParser method parseXMLObject.

public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    boolean useAmbiguities = xo.getAttribute(USE_AMBIGUITIES, false);
    int instanceCount = xo.getAttribute(INSTANCE_COUNT, 1);
    if (instanceCount < 1) {
        instanceCount = 1;
    }
    String ic = System.getProperty(BEAGLE_INSTANCE_COUNT);
    if (ic != null && ic.length() > 0) {
        instanceCount = Integer.parseInt(ic);
    }
    PatternList patternList = (PatternList) xo.getChild(PatternList.class);
    TreeModel treeModel = (TreeModel) xo.getChild(TreeModel.class);
    GammaSiteRateModel siteRateModel = (GammaSiteRateModel) xo.getChild(GammaSiteRateModel.class);
    FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
    BranchModel branchModel = (BranchModel) xo.getChild(BranchModel.class);
    if (branchModel == null) {
        SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
        if (substitutionModel == null) {
            substitutionModel = siteRateModel.getSubstitutionModel();
        }
        if (substitutionModel == null) {
            throw new XMLParseException("No substitution model available for TreeLikelihood: " + xo.getId());
        }
        branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
    }
    BranchRateModel branchRateModel = (BranchRateModel) xo.getChild(BranchRateModel.class);
    TipStatesModel tipStatesModel = (TipStatesModel) xo.getChild(TipStatesModel.class);
    //        if (xo.getChild(TipStatesModel.class) != null) {
    //            throw new XMLParseException("Sequence Error Models are not supported under BEAGLE yet. Please use Native BEAST Likelihood.");
    //        }
    PartialsRescalingScheme scalingScheme = PartialsRescalingScheme.DEFAULT;
    boolean delayScaling = true;
    if (xo.hasAttribute(SCALING_SCHEME)) {
        scalingScheme = PartialsRescalingScheme.parseFromString(xo.getStringAttribute(SCALING_SCHEME));
        if (scalingScheme == null)
            throw new XMLParseException("Unknown scaling scheme '" + xo.getStringAttribute(SCALING_SCHEME) + "' in " + "OldBeagleTreeLikelihood object '" + xo.getId());
    }
    if (xo.hasAttribute(DELAY_SCALING)) {
        delayScaling = xo.getBooleanAttribute(DELAY_SCALING);
    }
    Map<Set<String>, Parameter> partialsRestrictions = null;
    if (xo.hasChildNamed(PARTIALS_RESTRICTION)) {
        XMLObject cxo = xo.getChild(PARTIALS_RESTRICTION);
        TaxonList taxonList = (TaxonList) cxo.getChild(TaxonList.class);
        //            Parameter parameter = (Parameter) cxo.getChild(Parameter.class);
        try {
            TreeUtils.getLeavesForTaxa(treeModel, taxonList);
        } catch (TreeUtils.MissingTaxonException e) {
            throw new XMLParseException("Unable to parse taxon list: " + e.getMessage());
        }
        throw new XMLParseException("Restricting internal nodes is not yet implemented.  Contact Marc");
    }
    if (instanceCount == 1 || patternList.getPatternCount() < instanceCount) {
        return createTreeLikelihood(patternList, treeModel, branchModel, siteRateModel, branchRateModel, tipStatesModel, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
    }
    if (tipStatesModel != null) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with a TipStateModel (i.e., a sequence error model).");
    }
    List<Likelihood> likelihoods = new ArrayList<Likelihood>();
    for (int i = 0; i < instanceCount; i++) {
        Patterns subPatterns = new Patterns(patternList, i, instanceCount);
        AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(subPatterns, treeModel, branchModel, siteRateModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
        treeLikelihood.setId(xo.getId() + "_" + instanceCount);
        likelihoods.add(treeLikelihood);
    }
    return new CompoundLikelihood(likelihoods);
}

Example 9 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class BeagleTreeLikelihood method main.

public static void main(String[] args) {
    try {
        MathUtils.setSeed(666);
        System.out.println("Test case 1: simulateOnePartition");
        int sequenceLength = 1000;
        ArrayList<Partition> partitionsList = new ArrayList<Partition>();
        // create tree
        NewickImporter importer = new NewickImporter("(SimSeq1:73.7468,(SimSeq2:25.256989999999995,SimSeq3:45.256989999999995):18.48981);");
        Tree tree = importer.importTree(null);
        TreeModel treeModel = new TreeModel(tree);
        // create Frequency Model
        Parameter freqs = new Parameter.Default(new double[] { 0.25, 0.25, 0.25, 0.25 });
        FrequencyModel freqModel = new FrequencyModel(Nucleotides.INSTANCE, freqs);
        // create branch model
        Parameter kappa1 = new Parameter.Default(1, 1);
        Parameter kappa2 = new Parameter.Default(1, 1);
        HKY hky1 = new HKY(kappa1, freqModel);
        HKY hky2 = new HKY(kappa2, freqModel);
        HomogeneousBranchModel homogenousBranchSubstitutionModel = new HomogeneousBranchModel(hky1);
        List<SubstitutionModel> substitutionModels = new ArrayList<SubstitutionModel>();
        substitutionModels.add(hky1);
        substitutionModels.add(hky2);
        List<FrequencyModel> freqModels = new ArrayList<FrequencyModel>();
        freqModels.add(freqModel);
        Parameter epochTimes = new Parameter.Default(1, 20);
        // create branch rate model
        Parameter rate = new Parameter.Default(1, 0.001);
        BranchRateModel branchRateModel = new StrictClockBranchRates(rate);
        // create site model
        GammaSiteRateModel siteRateModel = new GammaSiteRateModel("siteModel");
        BranchModel homogeneousBranchModel = new HomogeneousBranchModel(hky1);
        BranchModel epochBranchModel = new EpochBranchModel(treeModel, substitutionModels, epochTimes);
        // create partition
        Partition partition1 = new //
        Partition(//
        treeModel, //
        homogenousBranchSubstitutionModel, //
        siteRateModel, //
        branchRateModel, //
        freqModel, // from
        0, // to
        sequenceLength - 1, // every
        1);
        partitionsList.add(partition1);
        // feed to sequence simulator and generate data
        BeagleSequenceSimulator simulator = new BeagleSequenceSimulator(partitionsList);
        Alignment alignment = simulator.simulate(false, false);
        BeagleTreeLikelihood nbtl = new BeagleTreeLikelihood(alignment, treeModel, homogeneousBranchModel, siteRateModel, branchRateModel, null, false, PartialsRescalingScheme.DEFAULT, false);
        System.out.println("nBTL(homogeneous) = " + nbtl.getLogLikelihood());
        nbtl = new BeagleTreeLikelihood(alignment, treeModel, epochBranchModel, siteRateModel, branchRateModel, null, false, PartialsRescalingScheme.DEFAULT, false);
        System.out.println("nBTL(epoch) = " + nbtl.getLogLikelihood());
    } catch (Exception e) {
        e.printStackTrace();
        System.exit(-1);
    }
// END: try-catch block
}

Example 10 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class PartitionData method createBranchModel.

public BranchModel createBranchModel() {
    BranchModel branchModel = null;
    if (this.substitutionModelIndex == 0) {
        // HKY
        Parameter kappa = new Parameter.Default(1, substitutionParameterValues[0]);
        FrequencyModel frequencyModel = this.createFrequencyModel();
        HKY hky = new HKY(kappa, frequencyModel);
        branchModel = new HomogeneousBranchModel(hky);
    } else if (this.substitutionModelIndex == 1) {
        // GTR
        Parameter ac = new Parameter.Default(1, substitutionParameterValues[1]);
        Parameter ag = new Parameter.Default(1, substitutionParameterValues[2]);
        Parameter at = new Parameter.Default(1, substitutionParameterValues[3]);
        Parameter cg = new Parameter.Default(1, substitutionParameterValues[4]);
        Parameter ct = new Parameter.Default(1, substitutionParameterValues[5]);
        Parameter gt = new Parameter.Default(1, substitutionParameterValues[6]);
        FrequencyModel frequencyModel = this.createFrequencyModel();
        GTR gtr = new GTR(ac, ag, at, cg, ct, gt, frequencyModel);
        branchModel = new HomogeneousBranchModel(gtr);
    } else if (this.substitutionModelIndex == 2) {
        // TN93
        Parameter kappa1 = new Parameter.Default(1, substitutionParameterValues[7]);
        Parameter kappa2 = new Parameter.Default(1, substitutionParameterValues[8]);
        FrequencyModel frequencyModel = this.createFrequencyModel();
        TN93 tn93 = new TN93(kappa1, kappa2, frequencyModel);
        branchModel = new HomogeneousBranchModel(tn93);
    } else if (this.substitutionModelIndex == 3) {
        // Yang Codon Model
        FrequencyModel frequencyModel = this.createFrequencyModel();
        Parameter kappa = new Parameter.Default(1, substitutionParameterValues[9]);
        Parameter omega = new Parameter.Default(1, substitutionParameterValues[10]);
        GY94CodonModel yangCodonModel = new GY94CodonModel(Codons.UNIVERSAL, omega, kappa, frequencyModel);
        branchModel = new HomogeneousBranchModel(yangCodonModel);
    } else if (this.substitutionModelIndex == 4) {
        // MG94CodonModel
        FrequencyModel frequencyModel = this.createFrequencyModel();
        Parameter alpha = new Parameter.Default(1, substitutionParameterValues[11]);
        Parameter beta = new Parameter.Default(1, substitutionParameterValues[12]);
        Parameter kappa = new Parameter.Default(1, substitutionParameterValues[13]);
        MG94HKYCodonModel mg94 = new MG94HKYCodonModel(Codons.UNIVERSAL, alpha, beta, kappa, frequencyModel);
        branchModel = new HomogeneousBranchModel(mg94);
    } else if (this.substitutionModelIndex == 5) {
        // Blosum62
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = Blosum62.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else if (this.substitutionModelIndex == 6) {
        // CPREV
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = CPREV.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else if (this.substitutionModelIndex == 7) {
        // Dayhoff
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = Dayhoff.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else if (this.substitutionModelIndex == 8) {
        // JTT
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = JTT.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else if (this.substitutionModelIndex == 9) {
        // LG
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = LG.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else if (this.substitutionModelIndex == 10) {
        // MTREV
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = MTREV.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else if (this.substitutionModelIndex == 11) {
        // WAG
        FrequencyModel frequencyModel = this.createFrequencyModel();
        EmpiricalRateMatrix rateMatrix = WAG.INSTANCE;
        EmpiricalAminoAcidModel empiricalAminoAcidModel = new EmpiricalAminoAcidModel(rateMatrix, frequencyModel);
        branchModel = new HomogeneousBranchModel(empiricalAminoAcidModel);
    } else {
        System.out.println("Not yet implemented");
    }
    return branchModel;
}