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Example 1 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class BeagleTreeLikelihood method main.

public static void main(String[] args) {
    try {
        MathUtils.setSeed(666);
        System.out.println("Test case 1: simulateOnePartition");
        int sequenceLength = 1000;
        ArrayList<Partition> partitionsList = new ArrayList<Partition>();
        // create tree
        NewickImporter importer = new NewickImporter("(SimSeq1:73.7468,(SimSeq2:25.256989999999995,SimSeq3:45.256989999999995):18.48981);");
        Tree tree = importer.importTree(null);
        TreeModel treeModel = new TreeModel(tree);
        // create Frequency Model
        Parameter freqs = new Parameter.Default(new double[] { 0.25, 0.25, 0.25, 0.25 });
        FrequencyModel freqModel = new FrequencyModel(Nucleotides.INSTANCE, freqs);
        // create branch model
        Parameter kappa1 = new Parameter.Default(1, 1);
        Parameter kappa2 = new Parameter.Default(1, 1);
        HKY hky1 = new HKY(kappa1, freqModel);
        HKY hky2 = new HKY(kappa2, freqModel);
        HomogeneousBranchModel homogenousBranchSubstitutionModel = new HomogeneousBranchModel(hky1);
        List<SubstitutionModel> substitutionModels = new ArrayList<SubstitutionModel>();
        substitutionModels.add(hky1);
        substitutionModels.add(hky2);
        List<FrequencyModel> freqModels = new ArrayList<FrequencyModel>();
        freqModels.add(freqModel);
        Parameter epochTimes = new Parameter.Default(1, 20);
        // create branch rate model
        Parameter rate = new Parameter.Default(1, 0.001);
        BranchRateModel branchRateModel = new StrictClockBranchRates(rate);
        // create site model
        GammaSiteRateModel siteRateModel = new GammaSiteRateModel("siteModel");
        BranchModel homogeneousBranchModel = new HomogeneousBranchModel(hky1);
        BranchModel epochBranchModel = new EpochBranchModel(treeModel, substitutionModels, epochTimes);
        // create partition
        Partition partition1 = new //
        Partition(//
        treeModel, //
        homogenousBranchSubstitutionModel, //
        siteRateModel, //
        branchRateModel, //
        freqModel, // from
        0, // to
        sequenceLength - 1, // every
        1);
        partitionsList.add(partition1);
        // feed to sequence simulator and generate data
        BeagleSequenceSimulator simulator = new BeagleSequenceSimulator(partitionsList);
        Alignment alignment = simulator.simulate(false, false);
        BeagleTreeLikelihood nbtl = new BeagleTreeLikelihood(alignment, treeModel, homogeneousBranchModel, siteRateModel, branchRateModel, null, false, PartialsRescalingScheme.DEFAULT, false);
        System.out.println("nBTL(homogeneous) = " + nbtl.getLogLikelihood());
        nbtl = new BeagleTreeLikelihood(alignment, treeModel, epochBranchModel, siteRateModel, branchRateModel, null, false, PartialsRescalingScheme.DEFAULT, false);
        System.out.println("nBTL(epoch) = " + nbtl.getLogLikelihood());
    } catch (Exception e) {
        e.printStackTrace();
        System.exit(-1);
    }
// END: try-catch block
}
Also used : FrequencyModel(dr.evomodel.substmodel.FrequencyModel) Partition(dr.app.beagle.tools.Partition) EpochBranchModel(dr.evomodel.branchmodel.EpochBranchModel) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) BranchModel(dr.evomodel.branchmodel.BranchModel) EpochBranchModel(dr.evomodel.branchmodel.EpochBranchModel) StrictClockBranchRates(dr.evomodel.branchratemodel.StrictClockBranchRates) SubstitutionModel(dr.evomodel.substmodel.SubstitutionModel) MarkovModulatedSubstitutionModel(dr.evomodel.substmodel.MarkovModulatedSubstitutionModel) BeagleSequenceSimulator(dr.app.beagle.tools.BeagleSequenceSimulator) TreeModel(dr.evomodel.tree.TreeModel) Alignment(dr.evolution.alignment.Alignment) DefaultBranchRateModel(dr.evomodel.branchratemodel.DefaultBranchRateModel) BranchRateModel(dr.evomodel.branchratemodel.BranchRateModel) NewickImporter(dr.evolution.io.NewickImporter) HKY(dr.evomodel.substmodel.nucleotide.HKY) Tree(dr.evolution.tree.Tree) Parameter(dr.inference.model.Parameter)

Example 2 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class DataLikelihoodTester2 method main.

public static void main(String[] args) {
    // turn off logging to avoid screen noise...
    Logger logger = Logger.getLogger("dr");
    logger.setUseParentHandlers(false);
    SimpleAlignment alignment = createAlignment(sequences, Nucleotides.INSTANCE);
    TreeModel treeModel;
    try {
        treeModel = createSpecifiedTree("((human:0.1,chimp:0.1):0.1,gorilla:0.2)");
    } catch (Exception e) {
        throw new RuntimeException("Unable to parse Newick tree");
    }
    System.out.print("\nTest BeagleTreeLikelihood (kappa = 1): ");
    // substitutionModel
    Parameter freqs = new Parameter.Default(new double[] { 0.25, 0.25, 0.25, 0.25 });
    Parameter kappa = new Parameter.Default(HKYParser.KAPPA, 1.0, 0, 100);
    FrequencyModel f = new FrequencyModel(Nucleotides.INSTANCE, freqs);
    HKY hky = new HKY(kappa, f);
    // siteModel
    double alpha = 0.5;
    GammaSiteRateModel siteRateModel = new GammaSiteRateModel("gammaModel", alpha, 4);
    // GammaSiteRateModel siteRateModel = new GammaSiteRateModel("siteRateModel");
    siteRateModel.setSubstitutionModel(hky);
    Parameter mu = new Parameter.Default(GammaSiteModelParser.SUBSTITUTION_RATE, 1.0, 0, Double.POSITIVE_INFINITY);
    siteRateModel.setRelativeRateParameter(mu);
    FrequencyModel f2 = new FrequencyModel(Nucleotides.INSTANCE, freqs);
    Parameter kappa2 = new Parameter.Default(HKYParser.KAPPA, 10.0, 0, 100);
    HKY hky2 = new HKY(kappa2, f2);
    GammaSiteRateModel siteRateModel2 = new GammaSiteRateModel("gammaModel", alpha, 4);
    siteRateModel2.setSubstitutionModel(hky2);
    siteRateModel2.setRelativeRateParameter(mu);
    // treeLikelihood
    SitePatterns patterns = new SitePatterns(alignment, null, 0, -1, 1, true);
    BranchModel branchModel = new HomogeneousBranchModel(siteRateModel.getSubstitutionModel(), siteRateModel.getSubstitutionModel().getFrequencyModel());
    BranchModel branchModel2 = new HomogeneousBranchModel(siteRateModel2.getSubstitutionModel(), siteRateModel2.getSubstitutionModel().getFrequencyModel());
    BranchRateModel branchRateModel = new DefaultBranchRateModel();
    BeagleTreeLikelihood treeLikelihood = new BeagleTreeLikelihood(patterns, treeModel, branchModel, siteRateModel, branchRateModel, null, false, PartialsRescalingScheme.AUTO, true);
    double logLikelihood = treeLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    System.out.print("\nTest BeagleDataLikelihoodDelegate (kappa = 1): ");
    BeagleDataLikelihoodDelegate dataLikelihoodDelegate = new BeagleDataLikelihoodDelegate(treeModel, patterns, branchModel, siteRateModel, false, false, PartialsRescalingScheme.NONE, false, PreOrderSettings.getDefault());
    TreeDataLikelihood treeDataLikelihood = new TreeDataLikelihood(dataLikelihoodDelegate, treeModel, branchRateModel);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    hky.setKappa(5.0);
    System.out.print("\nTest BeagleDataLikelihoodDelegate (kappa = 5): ");
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    System.out.print("\nTest BeagleDataLikelihoodDelegate (kappa = 10): ");
    dataLikelihoodDelegate = new BeagleDataLikelihoodDelegate(treeModel, patterns, branchModel2, siteRateModel2, false, false, PartialsRescalingScheme.NONE, false, PreOrderSettings.getDefault());
    treeDataLikelihood = new TreeDataLikelihood(dataLikelihoodDelegate, treeModel, branchRateModel);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    hky2.setKappa(11.0);
    System.out.print("\nTest BeagleDataLikelihoodDelegate (kappa = 11): ");
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    hky.setKappa(1.0);
    hky2.setKappa(10.0);
    MultiPartitionDataLikelihoodDelegate multiPartitionDataLikelihoodDelegate;
    System.out.print("\nTest MultiPartitionDataLikelihoodDelegate 1 partition (kappa = 1):");
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, Collections.singletonList((PatternList) patterns), Collections.singletonList((BranchModel) branchModel), Collections.singletonList((SiteRateModel) siteRateModel), true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood);
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    hky.setKappa(5.0);
    System.out.print("\nTest MultiPartitionDataLikelihoodDelegate 1 partition (kappa = 5):");
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    hky.setKappa(1.0);
    System.out.print("\nTest MultiPartitionDataLikelihoodDelegate 1 partition (kappa = 10):");
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, Collections.singletonList((PatternList) patterns), Collections.singletonList((BranchModel) branchModel2), Collections.singletonList((SiteRateModel) siteRateModel2), true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood);
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    System.out.print("\nTest MultiPartitionDataLikelihoodDelegate 2 partitions (kappa = 1, 10): ");
    List<PatternList> patternLists = new ArrayList<PatternList>();
    patternLists.add(patterns);
    patternLists.add(patterns);
    List<SiteRateModel> siteRateModels = new ArrayList<SiteRateModel>();
    siteRateModels.add(siteRateModel);
    siteRateModels.add(siteRateModel2);
    List<BranchModel> branchModels = new ArrayList<BranchModel>();
    branchModels.add(branchModel);
    branchModels.add(branchModel2);
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, patternLists, branchModels, siteRateModels, true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: this is 2x the logLikelihood of the 2nd partition)\n\n");
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    System.exit(0);
    // START ADDITIONAL TEST #1 - Guy Baele
    System.out.println("-- Test #1 SiteRateModels -- ");
    // alpha in partition 1 reject followed by alpha in partition 2 reject
    System.out.print("Adjust alpha in partition 1: ");
    siteRateModel.setAlpha(0.4);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    System.out.print("Return alpha in partition 1 to original value: ");
    siteRateModel.setAlpha(0.5);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + " (i.e. reject: OK)\n");
    System.out.print("Adjust alpha in partition 2: ");
    siteRateModel2.setAlpha(0.35);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    System.out.print("Return alpha in partition 2 to original value: ");
    siteRateModel2.setAlpha(0.5);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + " (i.e. reject: OK)\n");
    // alpha in partition 1 accept followed by alpha in partition 2 accept
    System.out.print("Adjust alpha in partition 1: ");
    siteRateModel.setAlpha(0.4);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    System.out.print("Adjust alpha in partition 2: ");
    siteRateModel2.setAlpha(0.35);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: same logLikelihood as only setting alpha in partition 2)");
    System.out.print("Return alpha in partition 1 to original value: ");
    siteRateModel.setAlpha(0.5);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: alpha in partition 2 has not been returned to original value yet)");
    System.out.print("Return alpha in partition 2 to original value: ");
    siteRateModel2.setAlpha(0.5);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + "\n");
    // adjusting alphas in both partitions without explicitly calling getLogLikelihood() in between
    System.out.print("Adjust both alphas in partitions 1 and 2: ");
    siteRateModel.setAlpha(0.4);
    siteRateModel2.setAlpha(0.35);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    System.out.print("Return alpha in partition 2 to original value: ");
    siteRateModel2.setAlpha(0.5);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: alpha in partition 1 has not been returned to original value yet)");
    System.out.print("Return alpha in partition 1 to original value: ");
    siteRateModel.setAlpha(0.5);
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood + "\n\n");
    // END ADDITIONAL TEST - Guy Baele
    // START ADDITIONAL TEST #2 - Guy Baele
    System.out.println("-- Test #2 SiteRateModels -- ");
    logLikelihood = treeDataLikelihood.getLogLikelihood();
    System.out.println("logLikelihood = " + logLikelihood);
    // 1 siteRateModel shared across 2 partitions
    siteRateModels = new ArrayList<SiteRateModel>();
    siteRateModels.add(siteRateModel);
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, patternLists, branchModels, siteRateModels, true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + "\n");
        System.out.print("Adjust alpha in shared siteRateModel: ");
        siteRateModel.setAlpha(0.4);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: same logLikelihood as only adjusted alpha for partition 1)");
        siteRateModel.setAlpha(0.5);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + "\n\n");
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    // END ADDITIONAL TEST - Guy Baele
    // START ADDITIONAL TEST #3 - Guy Baele
    System.out.println("-- Test #3 SiteRateModels -- ");
    siteRateModel = new GammaSiteRateModel("gammaModel");
    siteRateModel.setSubstitutionModel(hky);
    siteRateModel.setRelativeRateParameter(mu);
    siteRateModel2 = new GammaSiteRateModel("gammaModel2");
    siteRateModel2.setSubstitutionModel(hky2);
    siteRateModel2.setRelativeRateParameter(mu);
    siteRateModels = new ArrayList<SiteRateModel>();
    siteRateModels.add(siteRateModel);
    siteRateModels.add(siteRateModel2);
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, patternLists, branchModels, siteRateModels, true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + "\n");
        System.out.print("Adjust kappa in partition 1: ");
        hky.setKappa(5.0);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: logLikelihood has not changed?)");
        System.out.print("Return kappa in partition 1 to original value: ");
        hky.setKappa(1.0);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + "\n");
        System.out.print("Adjust kappa in partition 2: ");
        hky2.setKappa(11.0);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood);
        System.out.print("Return kappa in partition 2 to original value: ");
        hky2.setKappa(10.0);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.println("logLikelihood = " + logLikelihood + " (i.e. reject: OK)\n\n");
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    // END ADDITIONAL TEST - Guy Baele
    // START ADDITIONAL TEST #4 - Guy Baele
    System.out.println("-- Test #4 SiteRateModels -- ");
    SimpleAlignment secondAlignment = createAlignment(moreSequences, Nucleotides.INSTANCE);
    SitePatterns morePatterns = new SitePatterns(secondAlignment, null, 0, -1, 1, true);
    BeagleDataLikelihoodDelegate dataLikelihoodDelegateOne = new BeagleDataLikelihoodDelegate(treeModel, patterns, branchModel, siteRateModel, false, false, PartialsRescalingScheme.NONE, false, PreOrderSettings.getDefault());
    TreeDataLikelihood treeDataLikelihoodOne = new TreeDataLikelihood(dataLikelihoodDelegateOne, treeModel, branchRateModel);
    logLikelihood = treeDataLikelihoodOne.getLogLikelihood();
    System.out.println("\nBeagleDataLikelihoodDelegate logLikelihood partition 1 (kappa = 1) = " + logLikelihood);
    hky.setKappa(10.0);
    logLikelihood = treeDataLikelihoodOne.getLogLikelihood();
    System.out.println("BeagleDataLikelihoodDelegate logLikelihood partition 1 (kappa = 10) = " + logLikelihood);
    hky.setKappa(1.0);
    BeagleDataLikelihoodDelegate dataLikelihoodDelegateTwo = new BeagleDataLikelihoodDelegate(treeModel, morePatterns, branchModel2, siteRateModel2, false, false, PartialsRescalingScheme.NONE, false, PreOrderSettings.getDefault());
    TreeDataLikelihood treeDataLikelihoodTwo = new TreeDataLikelihood(dataLikelihoodDelegateTwo, treeModel, branchRateModel);
    logLikelihood = treeDataLikelihoodTwo.getLogLikelihood();
    System.out.println("BeagleDataLikelihoodDelegate logLikelihood partition 2 (kappa = 10) = " + logLikelihood + "\n");
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, Collections.singletonList((PatternList) patterns), Collections.singletonList((BranchModel) branchModel), Collections.singletonList((SiteRateModel) siteRateModel), true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.print("Test MultiPartitionDataLikelihoodDelegate 1st partition (kappa = 1):");
        System.out.println("logLikelihood = " + logLikelihood);
        hky.setKappa(10.0);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.print("Test MultiPartitionDataLikelihoodDelegate 1st partition (kappa = 10):");
        System.out.println("logLikelihood = " + logLikelihood);
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    hky.setKappa(1.0);
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, Collections.singletonList((PatternList) morePatterns), Collections.singletonList((BranchModel) branchModel2), Collections.singletonList((SiteRateModel) siteRateModel2), true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.print("Test MultiPartitionDataLikelihoodDelegate 2nd partition (kappa = 10):");
        System.out.println("logLikelihood = " + logLikelihood + "\n");
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
    patternLists = new ArrayList<PatternList>();
    patternLists.add(patterns);
    patternLists.add(morePatterns);
    try {
        multiPartitionDataLikelihoodDelegate = new MultiPartitionDataLikelihoodDelegate(treeModel, patternLists, branchModels, siteRateModels, true, PartialsRescalingScheme.NONE, false);
        treeDataLikelihood = new TreeDataLikelihood(multiPartitionDataLikelihoodDelegate, treeModel, branchRateModel);
        logLikelihood = treeDataLikelihood.getLogLikelihood();
        System.out.print("Test MultiPartitionDataLikelihoodDelegate 2 partitions (kappa = 1, 10): ");
        System.out.println("logLikelihood = " + logLikelihood + " (NOT OK: should be the sum of both separate logLikelihoods)\nKappa value of partition 2 is used to compute logLikelihood for both partitions?");
    } catch (DataLikelihoodDelegate.DelegateTypeException dte) {
        System.out.print("Failed to create multiPartitionDataLikelihoodDelegate instance (wrong resource type or no partitions, needs to be CUDA or OpenCL device with multiple partitions)");
    }
// END ADDITIONAL TEST - Guy Baele
}
Also used : FrequencyModel(dr.evomodel.substmodel.FrequencyModel) PatternList(dr.evolution.alignment.PatternList) ArrayList(java.util.ArrayList) Logger(java.util.logging.Logger) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) BranchModel(dr.evomodel.branchmodel.BranchModel) DefaultBranchRateModel(dr.evomodel.branchratemodel.DefaultBranchRateModel) SiteRateModel(dr.evomodel.siteratemodel.SiteRateModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) TreeModel(dr.evomodel.tree.TreeModel) DefaultTreeModel(dr.evomodel.tree.DefaultTreeModel) SimpleAlignment(dr.evolution.alignment.SimpleAlignment) SitePatterns(dr.evolution.alignment.SitePatterns) BeagleTreeLikelihood(dr.evomodel.treelikelihood.BeagleTreeLikelihood) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) DefaultBranchRateModel(dr.evomodel.branchratemodel.DefaultBranchRateModel) BranchRateModel(dr.evomodel.branchratemodel.BranchRateModel) HKY(dr.evomodel.substmodel.nucleotide.HKY) Parameter(dr.inference.model.Parameter)

Example 3 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class BalancedBeagleTreeLikelihoodParser method parseXMLObject.

public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    boolean useAmbiguities = xo.getAttribute(BeagleTreeLikelihoodParser.USE_AMBIGUITIES, false);
    /*int instanceCount = xo.getAttribute(INSTANCE_COUNT, 1);
        if (instanceCount < 1) {
            instanceCount = 1;
        }

        String ic = System.getProperty(BEAGLE_INSTANCE_COUNT);
        if (ic != null && ic.length() > 0) {
            instanceCount = Integer.parseInt(ic);
        }*/
    PatternList patternList = (PatternList) xo.getChild(PatternList.class);
    TreeModel treeModel = (TreeModel) xo.getChild(TreeModel.class);
    GammaSiteRateModel siteRateModel = (GammaSiteRateModel) xo.getChild(GammaSiteRateModel.class);
    FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
    BranchModel branchModel = (BranchModel) xo.getChild(BranchModel.class);
    if (branchModel == null) {
        SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
        if (substitutionModel == null) {
            substitutionModel = siteRateModel.getSubstitutionModel();
        }
        if (substitutionModel == null) {
            throw new XMLParseException("No substitution model available for TreeLikelihood: " + xo.getId());
        }
        branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
    }
    BranchRateModel branchRateModel = (BranchRateModel) xo.getChild(BranchRateModel.class);
    TipStatesModel tipStatesModel = (TipStatesModel) xo.getChild(TipStatesModel.class);
    // if (xo.getChild(TipStatesModel.class) != null) {
    // throw new XMLParseException("Sequence Error Models are not supported under BEAGLE yet. Please use Native BEAST Likelihood.");
    // }
    PartialsRescalingScheme scalingScheme = PartialsRescalingScheme.DEFAULT;
    if (xo.hasAttribute(BeagleTreeLikelihoodParser.SCALING_SCHEME)) {
        // scalingScheme = PartialsRescalingScheme.parseFromString(xo.getStringAttribute(BeagleTreeLikelihoodParser.SCALING_SCHEME));
        if (scalingScheme == null)
            throw new XMLParseException("Unknown scaling scheme '" + xo.getStringAttribute(BeagleTreeLikelihoodParser.SCALING_SCHEME) + "' in " + "OldBeagleTreeLikelihood object '" + xo.getId());
    }
    boolean delayScaling = true;
    Map<Set<String>, Parameter> partialsRestrictions = null;
    if (xo.hasChildNamed(PARTIALS_RESTRICTION)) {
        XMLObject cxo = xo.getChild(PARTIALS_RESTRICTION);
        TaxonList taxonList = (TaxonList) cxo.getChild(TaxonList.class);
        // Parameter parameter = (Parameter) cxo.getChild(Parameter.class);
        try {
            TreeUtils.getLeavesForTaxa(treeModel, taxonList);
        } catch (TreeUtils.MissingTaxonException e) {
            throw new XMLParseException("Unable to parse taxon list: " + e.getMessage());
        }
        throw new XMLParseException("Restricting internal nodes is not yet implemented.  Contact Marc");
    }
    /*if (instanceCount == 1 || patternList.getPatternCount() < instanceCount) {
            return createTreeLikelihood(
                    patternList,
                    treeModel,
                    branchModel,
                    siteRateModel,
                    branchRateModel,
                    tipStatesModel,
                    useAmbiguities,
                    scalingScheme,
                    partialsRestrictions,
                    xo
            );
        }*/
    // first run a test for instanceCount == 1
    System.err.println("\nTesting instanceCount == 1");
    Likelihood baseLikelihood = createTreeLikelihood(patternList, treeModel, branchModel, siteRateModel, branchRateModel, tipStatesModel, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
    double start = System.nanoTime();
    for (int i = 0; i < TEST_RUNS; i++) {
        baseLikelihood.makeDirty();
        baseLikelihood.getLogLikelihood();
    }
    double end = System.nanoTime();
    double baseResult = end - start;
    System.err.println("Evaluation took: " + baseResult);
    if (!(patternList instanceof SitePatterns)) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with BEAUti-selected codon partitioning.");
    }
    if (tipStatesModel != null) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with a TipStateModel (i.e., a sequence error model).");
    }
    // List<Likelihood> likelihoods = new ArrayList<Likelihood>();
    List<Likelihood> likelihoods = null;
    CompoundLikelihood compound = null;
    int instanceCount = 2;
    boolean optimal = false;
    while (optimal == false) {
        System.err.println("\nCreating instanceCount == " + instanceCount);
        likelihoods = new ArrayList<Likelihood>();
        for (int i = 0; i < instanceCount; i++) {
            Patterns subPatterns = new Patterns((SitePatterns) patternList, 0, 0, 1, i, instanceCount);
            AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(subPatterns, treeModel, branchModel, siteRateModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
            treeLikelihood.setId(xo.getId() + "_" + instanceCount);
            likelihoods.add(treeLikelihood);
        }
        // construct compoundLikelihood
        compound = new CompoundLikelihood(instanceCount, likelihoods);
        // test timings
        System.err.println("\nTesting instanceCount == " + instanceCount);
        start = System.nanoTime();
        for (int i = 0; i < TEST_RUNS; i++) {
            compound.makeDirty();
            compound.getLogLikelihood();
        }
        end = System.nanoTime();
        double newResult = end - start;
        System.err.println("Evaluation took: " + newResult);
        if (baseResult / newResult > TEST_CUTOFF) {
            instanceCount++;
            baseResult = newResult;
        } else {
            optimal = true;
            instanceCount--;
            System.err.println("\nCreating final BeagleTreeLikelihood with instanceCount: " + instanceCount);
            likelihoods = new ArrayList<Likelihood>();
            for (int i = 0; i < instanceCount; i++) {
                Patterns subPatterns = new Patterns((SitePatterns) patternList, 0, 0, 1, i, instanceCount);
                AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(subPatterns, treeModel, branchModel, siteRateModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
                treeLikelihood.setId(xo.getId() + "_" + instanceCount);
                likelihoods.add(treeLikelihood);
            }
            // construct compoundLikelihood
            compound = new CompoundLikelihood(instanceCount, likelihoods);
        }
    }
    return compound;
/*for (int i = 0; i < instanceCount; i++) {

            Patterns subPatterns = new Patterns((SitePatterns)patternList, 0, 0, 1, i, instanceCount);

            AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(
                    subPatterns,
                    treeModel,
                    branchModel,
                    siteRateModel,
                    branchRateModel,
                    null,
                    useAmbiguities,
                    scalingScheme,
                    partialsRestrictions,
                    xo);
            treeLikelihood.setId(xo.getId() + "_" + instanceCount);
            likelihoods.add(treeLikelihood);
        }

        return new CompoundLikelihood(likelihoods);*/
}
Also used : FrequencyModel(dr.evomodel.substmodel.FrequencyModel) Set(java.util.Set) CompoundLikelihood(dr.inference.model.CompoundLikelihood) Likelihood(dr.inference.model.Likelihood) BeagleTreeLikelihood(dr.evomodel.treelikelihood.BeagleTreeLikelihood) AbstractTreeLikelihood(dr.evomodel.treelikelihood.AbstractTreeLikelihood) PatternList(dr.evolution.alignment.PatternList) AbstractTreeLikelihood(dr.evomodel.treelikelihood.AbstractTreeLikelihood) PartialsRescalingScheme(dr.evomodel.treelikelihood.PartialsRescalingScheme) BranchModel(dr.evomodel.branchmodel.BranchModel) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) TreeModel(dr.evomodel.tree.TreeModel) Patterns(dr.evolution.alignment.Patterns) SitePatterns(dr.evolution.alignment.SitePatterns) TreeUtils(dr.evolution.tree.TreeUtils) SitePatterns(dr.evolution.alignment.SitePatterns) TaxonList(dr.evolution.util.TaxonList) CompoundLikelihood(dr.inference.model.CompoundLikelihood) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) SubstitutionModel(dr.evomodel.substmodel.SubstitutionModel) TipStatesModel(dr.evomodel.tipstatesmodel.TipStatesModel) BranchRateModel(dr.evomodel.branchratemodel.BranchRateModel) Parameter(dr.inference.model.Parameter)

Example 4 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class BeagleTreeLikelihoodParser method parseXMLObject.

public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    boolean useAmbiguities = xo.getAttribute(USE_AMBIGUITIES, false);
    int instanceCount = xo.getAttribute(INSTANCE_COUNT, 1);
    if (instanceCount < 1) {
        instanceCount = 1;
    }
    String ic = System.getProperty(BEAGLE_INSTANCE_COUNT);
    if (ic != null && ic.length() > 0) {
        instanceCount = Integer.parseInt(ic);
    }
    PatternList patternList = (PatternList) xo.getChild(PatternList.class);
    MutableTreeModel treeModel = (MutableTreeModel) xo.getChild(MutableTreeModel.class);
    GammaSiteRateModel siteRateModel = (GammaSiteRateModel) xo.getChild(GammaSiteRateModel.class);
    FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
    BranchModel branchModel = (BranchModel) xo.getChild(BranchModel.class);
    if (branchModel == null) {
        SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
        if (substitutionModel == null) {
            substitutionModel = siteRateModel.getSubstitutionModel();
        }
        if (substitutionModel == null) {
            throw new XMLParseException("No substitution model available for TreeLikelihood: " + xo.getId());
        }
        branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
    }
    BranchRateModel branchRateModel = (BranchRateModel) xo.getChild(BranchRateModel.class);
    if (branchModel instanceof EpochBranchModel && rootFreqModel != null) {
        EpochBranchModel epochBranchModel = (EpochBranchModel) branchModel;
        epochBranchModel.setRootFrequencyModel(rootFreqModel);
    }
    TipStatesModel tipStatesModel = (TipStatesModel) xo.getChild(TipStatesModel.class);
    // if (xo.getChild(TipStatesModel.class) != null) {
    // throw new XMLParseException("Sequence Error Models are not supported under BEAGLE yet. Please use Native BEAST Likelihood.");
    // }
    PartialsRescalingScheme scalingScheme = PartialsRescalingScheme.DEFAULT;
    boolean delayScaling = true;
    if (xo.hasAttribute(SCALING_SCHEME)) {
        scalingScheme = PartialsRescalingScheme.parseFromString(xo.getStringAttribute(SCALING_SCHEME));
        if (scalingScheme == null)
            throw new XMLParseException("Unknown scaling scheme '" + xo.getStringAttribute(SCALING_SCHEME) + "' in " + "OldBeagleTreeLikelihood object '" + xo.getId());
    }
    if (xo.hasAttribute(DELAY_SCALING)) {
        delayScaling = xo.getBooleanAttribute(DELAY_SCALING);
    }
    Map<Set<String>, Parameter> partialsRestrictions = null;
    if (xo.hasChildNamed(PARTIALS_RESTRICTION)) {
        XMLObject cxo = xo.getChild(PARTIALS_RESTRICTION);
        TaxonList taxonList = (TaxonList) cxo.getChild(TaxonList.class);
        // Parameter parameter = (Parameter) cxo.getChild(Parameter.class);
        try {
            TreeUtils.getLeavesForTaxa(treeModel, taxonList);
        } catch (TreeUtils.MissingTaxonException e) {
            throw new XMLParseException("Unable to parse taxon list: " + e.getMessage());
        }
        throw new XMLParseException("Restricting internal nodes is not yet implemented.  Contact Marc");
    }
    int beagleThreadCount = -1;
    if (System.getProperty(BEAGLE_THREAD_COUNT) != null) {
        beagleThreadCount = Integer.parseInt(System.getProperty(BEAGLE_THREAD_COUNT));
    }
    if (beagleThreadCount == -1) {
        // the default is -1 threads (automatic thread pool size) but an XML attribute can override it
        int threadCount = xo.getAttribute(THREADS, -1);
        if (System.getProperty(THREAD_COUNT) != null) {
            threadCount = Integer.parseInt(System.getProperty(THREAD_COUNT));
        }
        // Todo: allow for different number of threads per beagle instance according to pattern counts
        if (threadCount >= 0) {
            System.setProperty(BEAGLE_THREAD_COUNT, Integer.toString(threadCount / instanceCount));
        }
    }
    if (instanceCount == 1 || patternList.getPatternCount() < instanceCount) {
        return createTreeLikelihood(patternList, treeModel, branchModel, siteRateModel, branchRateModel, tipStatesModel, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
    }
    if (tipStatesModel != null) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with a TipStateModel (i.e., a sequence error model).");
    }
    List<Likelihood> likelihoods = new ArrayList<Likelihood>();
    for (int i = 0; i < instanceCount; i++) {
        Patterns subPatterns = new Patterns(patternList, i, instanceCount);
        AbstractTreeLikelihood treeLikelihood = createTreeLikelihood(subPatterns, treeModel, branchModel, siteRateModel, branchRateModel, null, useAmbiguities, scalingScheme, delayScaling, partialsRestrictions, xo);
        treeLikelihood.setId(xo.getId() + "_" + instanceCount);
        likelihoods.add(treeLikelihood);
    }
    return new CompoundLikelihood(likelihoods);
}
Also used : FrequencyModel(dr.evomodel.substmodel.FrequencyModel) Set(java.util.Set) CompoundLikelihood(dr.inference.model.CompoundLikelihood) Likelihood(dr.inference.model.Likelihood) BeagleTreeLikelihood(dr.evomodel.treelikelihood.BeagleTreeLikelihood) AbstractTreeLikelihood(dr.evomodel.treelikelihood.AbstractTreeLikelihood) PatternList(dr.evolution.alignment.PatternList) ArrayList(java.util.ArrayList) AbstractTreeLikelihood(dr.evomodel.treelikelihood.AbstractTreeLikelihood) PartialsRescalingScheme(dr.evomodel.treelikelihood.PartialsRescalingScheme) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) BranchModel(dr.evomodel.branchmodel.BranchModel) EpochBranchModel(dr.evomodel.branchmodel.EpochBranchModel) MutableTreeModel(dr.evolution.tree.MutableTreeModel) Patterns(dr.evolution.alignment.Patterns) TreeUtils(dr.evolution.tree.TreeUtils) EpochBranchModel(dr.evomodel.branchmodel.EpochBranchModel) TaxonList(dr.evolution.util.TaxonList) CompoundLikelihood(dr.inference.model.CompoundLikelihood) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) SubstitutionModel(dr.evomodel.substmodel.SubstitutionModel) TipStatesModel(dr.evomodel.tipstatesmodel.TipStatesModel) BranchRateModel(dr.evomodel.branchratemodel.BranchRateModel) Parameter(dr.inference.model.Parameter)

Example 5 with HomogeneousBranchModel

use of dr.evomodel.branchmodel.HomogeneousBranchModel in project beast-mcmc by beast-dev.

the class TreeDataLikelihoodParser method parseXMLObject.

public Object parseXMLObject(XMLObject xo) throws XMLParseException {
    boolean useAmbiguities = xo.getAttribute(USE_AMBIGUITIES, false);
    boolean usePreOrder = xo.getAttribute(USE_PREORDER, false);
    boolean branchRateDerivative = xo.getAttribute(BRANCHRATE_DERIVATIVE, usePreOrder);
    boolean branchInfinitesimalDerivative = xo.getAttribute(BRANCHINFINITESIMAL_DERIVATIVE, false);
    if (usePreOrder != (branchRateDerivative || branchInfinitesimalDerivative)) {
        throw new RuntimeException("Need to specify derivative types.");
    }
    PreOrderSettings settings = new PreOrderSettings(usePreOrder, branchRateDerivative, branchInfinitesimalDerivative);
    // TreeDataLikelihood doesn't currently support Instances defined from the command line
    // int instanceCount = xo.getAttribute(INSTANCE_COUNT, 1);
    // if (instanceCount < 1) {
    // instanceCount = 1;
    // }
    // 
    // String ic = System.getProperty(BEAGLE_INSTANCE_COUNT);
    // if (ic != null && ic.length() > 0) {
    // instanceCount = Integer.parseInt(ic);
    // }
    List<PatternList> patternLists = new ArrayList<PatternList>();
    List<SiteRateModel> siteRateModels = new ArrayList<SiteRateModel>();
    List<BranchModel> branchModels = new ArrayList<BranchModel>();
    boolean hasSinglePartition = false;
    PatternList patternList = (PatternList) xo.getChild(PatternList.class);
    if (patternList != null) {
        hasSinglePartition = true;
        patternLists.add(patternList);
        GammaSiteRateModel siteRateModel = (GammaSiteRateModel) xo.getChild(GammaSiteRateModel.class);
        siteRateModels.add(siteRateModel);
        FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
        BranchModel branchModel = (BranchModel) xo.getChild(BranchModel.class);
        if (branchModel == null) {
            SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
            if (substitutionModel == null) {
                substitutionModel = siteRateModel.getSubstitutionModel();
            }
            if (substitutionModel == null) {
                throw new XMLParseException("No substitution model available for partition in DataTreeLikelihood: " + xo.getId());
            }
            branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
        }
        branchModels.add(branchModel);
    }
    int k = 0;
    for (int i = 0; i < xo.getChildCount(); i++) {
        if (xo.getChildName(i).equals(PARTITION)) {
            if (hasSinglePartition) {
                throw new XMLParseException("Either a single set of patterns should be given or multiple 'partitions' elements within DataTreeLikelihood: " + xo.getId());
            }
            k += 1;
            XMLObject cxo = (XMLObject) xo.getChild(i);
            patternList = (PatternList) cxo.getChild(PatternList.class);
            patternLists.add(patternList);
            GammaSiteRateModel siteRateModel = (GammaSiteRateModel) cxo.getChild(GammaSiteRateModel.class);
            siteRateModels.add(siteRateModel);
            FrequencyModel rootFreqModel = (FrequencyModel) xo.getChild(FrequencyModel.class);
            BranchModel branchModel = (BranchModel) cxo.getChild(BranchModel.class);
            if (branchModel == null) {
                SubstitutionModel substitutionModel = (SubstitutionModel) xo.getChild(SubstitutionModel.class);
                if (substitutionModel == null) {
                    substitutionModel = siteRateModel.getSubstitutionModel();
                }
                if (substitutionModel == null) {
                    throw new XMLParseException("No substitution model available for partition " + k + " in DataTreeLikelihood: " + xo.getId());
                }
                branchModel = new HomogeneousBranchModel(substitutionModel, rootFreqModel);
            }
            branchModels.add(branchModel);
            BranchRateModel branchRateModel = (BranchRateModel) cxo.getChild(BranchRateModel.class);
            if (branchRateModel != null) {
                throw new XMLParseException("Partitions are not currently allowed their own BranchRateModel in TreeDataLikelihood object '" + xo.getId());
            }
        }
    }
    if (patternLists.size() == 0) {
        throw new XMLParseException("Either a single set of patterns should be given or multiple 'partitions' elements within DataTreeLikelihood: " + xo.getId());
    }
    Tree treeModel = (Tree) xo.getChild(Tree.class);
    BranchRateModel branchRateModel = (BranchRateModel) xo.getChild(BranchRateModel.class);
    if (branchRateModel == null) {
        throw new XMLParseException("BranchRateModel missing from TreeDataLikelihood object '" + xo.getId());
    // branchRateModel = new DefaultBranchRateModel();
    }
    TipStatesModel tipStatesModel = (TipStatesModel) xo.getChild(TipStatesModel.class);
    final boolean preferGPU = xo.getAttribute(PREFER_GPU, false);
    PartialsRescalingScheme scalingScheme = PartialsRescalingScheme.DEFAULT;
    if (xo.hasAttribute(SCALING_SCHEME)) {
        scalingScheme = PartialsRescalingScheme.parseFromString(xo.getStringAttribute(SCALING_SCHEME));
        if (scalingScheme == null)
            throw new XMLParseException("Unknown scaling scheme '" + xo.getStringAttribute(SCALING_SCHEME) + "' in " + "TreeDataLikelihood object '" + xo.getId());
    }
    final boolean delayScaling = xo.getAttribute(DELAY_SCALING, true);
    if (tipStatesModel != null) {
        throw new XMLParseException("BEAGLE_INSTANCES option cannot be used with a TipStateModel (i.e., a sequence error model).");
    }
    return createTreeDataLikelihood(patternLists, branchModels, siteRateModels, treeModel, branchRateModel, null, useAmbiguities, preferGPU, scalingScheme, delayScaling, settings);
}
Also used : FrequencyModel(dr.evomodel.substmodel.FrequencyModel) PatternList(dr.evolution.alignment.PatternList) ArrayList(java.util.ArrayList) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) PartialsRescalingScheme(dr.evomodel.treelikelihood.PartialsRescalingScheme) BranchModel(dr.evomodel.branchmodel.BranchModel) HomogeneousBranchModel(dr.evomodel.branchmodel.HomogeneousBranchModel) SubstitutionModel(dr.evomodel.substmodel.SubstitutionModel) GammaSiteRateModel(dr.evomodel.siteratemodel.GammaSiteRateModel) SiteRateModel(dr.evomodel.siteratemodel.SiteRateModel) TipStatesModel(dr.evomodel.tipstatesmodel.TipStatesModel) PreOrderSettings(dr.evomodel.treedatalikelihood.PreOrderSettings) BranchRateModel(dr.evomodel.branchratemodel.BranchRateModel) Tree(dr.evolution.tree.Tree)

Aggregations

HomogeneousBranchModel (dr.evomodel.branchmodel.HomogeneousBranchModel)20 FrequencyModel (dr.evomodel.substmodel.FrequencyModel)19 BranchRateModel (dr.evomodel.branchratemodel.BranchRateModel)18 GammaSiteRateModel (dr.evomodel.siteratemodel.GammaSiteRateModel)18 Parameter (dr.inference.model.Parameter)16 BranchModel (dr.evomodel.branchmodel.BranchModel)12 DefaultBranchRateModel (dr.evomodel.branchratemodel.DefaultBranchRateModel)12 ArrayList (java.util.ArrayList)12 HKY (dr.evomodel.substmodel.nucleotide.HKY)11 DefaultTreeModel (dr.evomodel.tree.DefaultTreeModel)11 Partition (dr.app.beagle.tools.Partition)10 TreeModel (dr.evomodel.tree.TreeModel)10 BeagleSequenceSimulator (dr.app.beagle.tools.BeagleSequenceSimulator)9 NewickImporter (dr.evolution.io.NewickImporter)9 Tree (dr.evolution.tree.Tree)9 SubstitutionModel (dr.evomodel.substmodel.SubstitutionModel)8 BeagleTreeLikelihood (dr.evomodel.treelikelihood.BeagleTreeLikelihood)7 PatternList (dr.evolution.alignment.PatternList)6 ImportException (dr.evolution.io.Importer.ImportException)6 IOException (java.io.IOException)6