Examples with Pathway org.vcell.pathway.Pathway used on opensource projects

Example 1 with Pathway

use of org.vcell.pathway.Pathway in project vcell by virtualcell.

the class PathwayReaderBiopax3 method addContentControl.

private boolean addContentControl(Control control, Element element, Element childElement) {
    if (addContentInteraction(control, element, childElement)) {
        return true;
    }
    /**
     * InteractionImpl controlledInteraction
     * Pathway controlledPathway
     * String controlType
     * ArrayList<Pathway> pathwayControllers
     * ArrayList<PhysicalEntity> physicalControllers
     */
    if (childElement.getName().equals("controller")) {
        // if (resourceAttribute != null){
        if (childElement.getChildren().size() == 0) {
            // if there are no children it must be a resource inside another object
            // we don't know yet whether it's Interaction or Pathway, we make a proxy for each
            // at the time when we solve the references we'll find out which is fake
            PhysicalEntityProxy proxyE = new PhysicalEntityProxy();
            addAttributes(proxyE, childElement);
            pathwayModel.add(proxyE);
            control.addPhysicalController(proxyE);
            PathwayProxy proxyP = new PathwayProxy();
            addAttributes(proxyP, childElement);
            pathwayModel.add(proxyP);
            control.getPathwayControllers().add(proxyP);
            return true;
        } else {
            for (Object child : element.getChildren()) {
                if (child instanceof Element) {
                    if (((Element) child).getName().equals("Pathway")) {
                        Pathway thingie = addObjectPathway((Element) child);
                        control.getPathwayControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("Complex")) {
                        Complex thingie = addObjectComplex((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("Dna")) {
                        Dna thingie = addObjectDna((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("DnaRegion")) {
                        DnaRegion thingie = addObjectDnaRegion((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("Rna")) {
                        Rna thingie = addObjectRna((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("RnaRegion")) {
                        RnaRegion thingie = addObjectRnaRegion((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("Protein")) {
                        Protein thingie = addObjectProtein((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else if (((Element) child).getName().equals("SmallMolecule")) {
                        SmallMolecule thingie = addObjectSmallMolecule((Element) child);
                        control.getPhysicalControllers().add(thingie);
                        return true;
                    } else {
                        return false;
                    }
                }
            }
        }
        return false;
    } else if (childElement.getName().equals("controlled")) {
        if (childElement.getChildren().size() == 0) {
            InteractionProxy proxyI = new InteractionProxy();
            addAttributes(proxyI, childElement);
            pathwayModel.add(proxyI);
            control.setControlledInteraction(proxyI);
            PathwayProxy proxyP = new PathwayProxy();
            addAttributes(proxyP, childElement);
            pathwayModel.add(proxyP);
            control.setControlledPathway(proxyP);
            return true;
        } else {
            for (Object child : childElement.getChildren()) {
                if (child instanceof Element) {
                    if (((Element) child).getName().equals("Pathway")) {
                        Pathway thingie = addObjectPathway((Element) child);
                        control.setControlledPathway(thingie);
                        return true;
                    } else {
                        Interaction thingie = (Interaction) addObjectBioPaxObjectSubclass((Element) child);
                        if (thingie == null) {
                            return false;
                        } else {
                            control.setControlledInteraction(thingie);
                            return true;
                        }
                    }
                // if(((Element)child).getName().equals("Pathway")) {
                // Pathway thingie = addObjectPathway((Element)child);
                // control.setControlledPathway(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Interaction")) {
                // Interaction thingie = addObjectInteraction((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Control")) {
                // Control thingie = addObjectControl((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Modulation")) {
                // Modulation thingie = addObjectModulation((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Catalysis")) {
                // Catalysis thingie = addObjectCatalysis((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("TemplateReactionRegulation")) {
                // TemplateReactionRegulation thingie = addObjectTemplateReactionRegulation((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Conversion")) {
                // Conversion thingie = addObjectConversion((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("BiochemicalReaction")) {
                // BiochemicalReaction thingie = addObjectBiochemicalReaction((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("TransportWithBiochemicalReaction")) {
                // TransportWithBiochemicalReaction thingie = addObjectTransportWithBiochemicalReaction((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("ComplexAssembly")) {
                // ComplexAssembly thingie = addObjectComplexAssembly((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Degradation")) {
                // Degradation thingie = addObjectDegradation((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("Transport")) {
                // Transport thingie = addObjectTransport((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("GeneticInteraction")) {
                // GeneticInteraction thingie = addObjectGeneticInteraction((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("MolecularInteraction")) {
                // MolecularInteraction thingie = addObjectMolecularInteraction((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else if(((Element)child).getName().equals("TemplateReaction")) {
                // TemplateReaction thingie = addObjectTemplateReaction((Element)child);
                // control.setControlledInteraction(thingie);
                // return true;
                // } else {
                // return false;
                // }
                }
            }
        }
        return false;
    } else if (childElement.getName().equals("controlType")) {
        control.setControlType(childElement.getTextTrim());
        return true;
    } else {
        return false;
    }
}

Example 2 with Pathway

use of org.vcell.pathway.Pathway in project vcell by virtualcell.

the class PathwayProducerBiopax3 method addContentPathwayStep.

// stepProcess 	Interaction 	multiple
// stepProcess 	Pathway 		multiple
// nextStep 		PathwayStep 	multiple
// evidence 		Evidence 		multiple
private Element addContentPathwayStep(BioPaxObject bpObject, Element element) {
    element = addContentUtilityClass(bpObject, element);
    PathwayStep ob = (PathwayStep) bpObject;
    Element tmpElement = null;
    if (ob.getStepProcessInteraction() != null && ob.getStepProcessInteraction().size() > 0) {
        List<Interaction> list = ob.getStepProcessInteraction();
        for (Interaction item : list) {
            tmpElement = new Element("stepProcess", bp);
            addIDToProperty(tmpElement, item);
            mustPrintObject(item);
            element.addContent(tmpElement);
        }
    }
    if (ob.getStepProcessPathway() != null && ob.getStepProcessPathway().size() > 0) {
        List<Pathway> list = ob.getStepProcessPathway();
        for (Pathway item : list) {
            tmpElement = new Element("stepProcess", bp);
            addIDToProperty(tmpElement, item);
            mustPrintObject(item);
            element.addContent(tmpElement);
        }
    }
    if (ob.getNextStep() != null && ob.getNextStep().size() > 0) {
        List<PathwayStep> list = ob.getNextStep();
        for (PathwayStep item : list) {
            tmpElement = new Element("nextStep", bp);
            addIDToProperty(tmpElement, item);
            mustPrintObject(item);
            element.addContent(tmpElement);
        }
    }
    if (ob.getEvidence() != null && ob.getEvidence().size() > 0) {
        List<Evidence> list = ob.getEvidence();
        for (Evidence item : list) {
            tmpElement = new Element("evidence", bp);
            addIDToProperty(tmpElement, item);
            mustPrintObject(item);
            element.addContent(tmpElement);
        }
    }
    return element;
}

Example 3 with Pathway

use of org.vcell.pathway.Pathway in project vcell by virtualcell.

the class BioModelEditorConversionTableModel method refreshData.

private void refreshData() {
    if (bioModel == null || bioModel.getPathwayModel() == null || bioPaxObjects == null) {
        setData(null);
        return;
    }
    // function I :: get selected objects only
    // create ConversionTableRow objects
    allPathwayObjectList = new ArrayList<ConversionTableRow>();
    convertedBPObjects = new HashSet<BioPaxObject>();
    printObjects(bioPaxObjects);
    BioModel.printBpModelObjects(bioModel.getPathwayModel().getBiopaxObjects());
    // BioModel.printBpRelationshipObjects(bioModel.getRelationshipModel().getBioPaxObjects());	// derived; the bpObjects that are part of a relationship
    BioModel.printRelationships(bioModel.getRelationshipModel().getRelationshipObjects());
    System.out.println("----------------------------------------------------------------------");
    for (BioPaxObject bpo : bioPaxObjects) {
        if (bpo instanceof Conversion) {
            if (bioModel.getRelationshipModel().getRelationshipObjects(bpo).size() == 0) {
                Conversion conversion = (Conversion) bpo;
                ArrayList<String> nameList = conversion.getName();
                String interactionId = conversion.getID();
                String interactionLabel = nameList.isEmpty() ? conversion.getIDShort() : nameList.get(0);
                ConversionTableRow newConversionTableRow = createTableRow(conversion, interactionId, interactionLabel, "Conversion", 1.0, null);
                allPathwayObjectList.add(newConversionTableRow);
                convertedBPObjects.add(bpo);
                ArrayList<Stoichiometry> stoichiometryList = conversion.getParticipantStoichiometry();
                // stoichiometryMap problem:
                // how to deal with the case that the same object occurs on both left and right sides
                HashMap<PhysicalEntity, Double> stoichiometryMap = createStoichiometryMap(stoichiometryList);
                // reactant
                for (BioPaxObject bpObject1 : conversion.getLeft()) {
                    Double stoich = 1.0;
                    if (stoichiometryMap.get((PhysicalEntity) bpObject1) != null) {
                        stoich = stoichiometryMap.get((PhysicalEntity) bpObject1);
                    }
                    ConversionTableRow conversionTableRow;
                    if (bioModel.getRelationshipModel().getRelationshipObjects(bpObject1).isEmpty()) {
                        if (conversion instanceof Transport)
                            conversionTableRow = createTableRowForTransportParticipant(bpObject1, interactionId, interactionLabel, "Reactant", stoich, null);
                        else
                            conversionTableRow = createTableRow(bpObject1, interactionId, interactionLabel, "Reactant", stoich, null);
                    } else {
                        if (conversion instanceof Transport)
                            conversionTableRow = createTableRowForTransportParticipant(bpObject1, interactionId, interactionLabel, "Reactant", stoich, bioModel.getRelationshipModel().getRelationshipObjects(bpObject1));
                        else
                            conversionTableRow = createTableRow(bpObject1, interactionId, interactionLabel, "Reactant", stoich, bioModel.getRelationshipModel().getRelationshipObjects(bpObject1));
                    }
                    allPathwayObjectList.add(conversionTableRow);
                    convertedBPObjects.add(bpObject1);
                }
                // product
                for (BioPaxObject bpObject1 : conversion.getRight()) {
                    Double stoich = 1.0;
                    if (stoichiometryMap.get((PhysicalEntity) bpObject1) != null) {
                        stoich = stoichiometryMap.get((PhysicalEntity) bpObject1);
                    }
                    ConversionTableRow conversionTableRow;
                    if (bioModel.getRelationshipModel().getRelationshipObjects(bpObject1).isEmpty()) {
                        if (conversion instanceof Transport)
                            conversionTableRow = createTableRowForTransportParticipant(bpObject1, interactionId, interactionLabel, "Product", stoich, null);
                        else
                            conversionTableRow = createTableRow(bpObject1, interactionId, interactionLabel, "Product", stoich, null);
                    } else {
                        if (conversion instanceof Transport)
                            conversionTableRow = createTableRowForTransportParticipant(bpObject1, interactionId, interactionLabel, "Product", stoich, bioModel.getRelationshipModel().getRelationshipObjects(bpObject1));
                        else
                            conversionTableRow = createTableRow(bpObject1, interactionId, interactionLabel, "Product", stoich, bioModel.getRelationshipModel().getRelationshipObjects(bpObject1));
                    }
                    allPathwayObjectList.add(conversionTableRow);
                    convertedBPObjects.add(bpObject1);
                }
                // control
                for (BioPaxObject bpObject : bioModel.getPathwayModel().getBiopaxObjects()) {
                    if (bpObject instanceof Control) {
                        Control control = (Control) bpObject;
                        if (control instanceof Catalysis) {
                            // catalysis
                            if (BioPAXUtil.getControlledNonControlInteraction(control) == conversion) {
                                for (PhysicalEntity pe : ((Catalysis) control).getPhysicalControllers()) {
                                    ConversionTableRow conversionTableRow;
                                    if (bioModel.getRelationshipModel().getRelationshipObjects(pe).isEmpty()) {
                                        conversionTableRow = createTableRow(pe, interactionId, interactionLabel, "Catalyst", 1.0, null);
                                    } else {
                                        conversionTableRow = createTableRow(pe, interactionId, interactionLabel, "Catalyst", 1.0, bioModel.getRelationshipModel().getRelationshipObjects(pe));
                                    }
                                    allPathwayObjectList.add(conversionTableRow);
                                    convertedBPObjects.add(pe);
                                }
                            }
                        } else {
                            // other control types
                            if (BioPAXUtil.getControlledNonControlInteraction(control) == conversion) {
                                for (PhysicalEntity pe : control.getPhysicalControllers()) {
                                    ConversionTableRow conversionTableRow;
                                    if (bioModel.getRelationshipModel().getRelationshipObjects(pe).isEmpty()) {
                                        conversionTableRow = createTableRow(pe, interactionId, interactionLabel, "Control", 1.0, null);
                                    } else {
                                        conversionTableRow = createTableRow(pe, interactionId, interactionLabel, "Control", 1.0, bioModel.getRelationshipModel().getRelationshipObjects(pe));
                                    }
                                    allPathwayObjectList.add(conversionTableRow);
                                    convertedBPObjects.add(pe);
                                }
                            }
                        }
                    }
                }
            }
        } else if (bpo instanceof Catalysis) {
            for (PhysicalEntity pe : ((Catalysis) bpo).getPhysicalControllers()) {
                if (!convertedBPObjects.contains(pe)) {
                    ConversionTableRow conversionTableRow;
                    if (bioModel.getRelationshipModel().getRelationshipObjects(bpo).isEmpty()) {
                        conversionTableRow = createTableRow(pe, "", "", "Catalyst", 1.0, null);
                    } else {
                        conversionTableRow = createTableRow(pe, "", "", "Catalyst", 1.0, bioModel.getRelationshipModel().getRelationshipObjects(bpo));
                    }
                    allPathwayObjectList.add(conversionTableRow);
                    convertedBPObjects.add(pe);
                }
            }
            for (Pathway pathway : ((Catalysis) bpo).getPathwayControllers()) {
            // TODO
            }
        } else if (bpo instanceof Control) {
            for (PhysicalEntity pe : ((Catalysis) bpo).getPhysicalControllers()) {
                if (!convertedBPObjects.contains(pe)) {
                    ConversionTableRow conversionTableRow;
                    if (bioModel.getRelationshipModel().getRelationshipObjects(bpo).isEmpty()) {
                        conversionTableRow = createTableRow(pe, "", "", "Control", 1.0, null);
                    } else {
                        conversionTableRow = createTableRow(pe, "", "", "Control", 1.0, bioModel.getRelationshipModel().getRelationshipObjects(bpo));
                    }
                    allPathwayObjectList.add(conversionTableRow);
                    convertedBPObjects.add(pe);
                }
            }
            for (Pathway pathway : ((Catalysis) bpo).getPathwayControllers()) {
            // TODO
            }
        }
    }
    // 2nd pass - entities selected as themselves
    for (BioPaxObject bpo : bioPaxObjects) {
        if (bpo instanceof PhysicalEntity) {
            if (bioModel.getRelationshipModel().getRelationshipObjects(bpo).size() == 0) {
                PhysicalEntity physicalEntityObject = (PhysicalEntity) bpo;
                // we add standalone selected entities, only if they were not already added as part of any reaction
                if (!convertedBPObjects.contains(physicalEntityObject)) {
                    ConversionTableRow conversionTableRow = createTableRow(physicalEntityObject, "", "", "", 1.0, null);
                    allPathwayObjectList.add(conversionTableRow);
                    convertedBPObjects.add(physicalEntityObject);
                }
            }
        }
    }
    // apply text search function for particular columns
    ArrayList<ConversionTableRow> pathwayObjectList = new ArrayList<ConversionTableRow>();
    if (searchText == null || searchText.length() == 0) {
        pathwayObjectList.addAll(allPathwayObjectList);
    } else {
        String lowerCaseSearchText = searchText.toLowerCase();
        for (ConversionTableRow rs : allPathwayObjectList) {
            BioPaxObject bpObject = rs.getBioPaxObject();
            if (rs.interactionLabel().toLowerCase().contains(lowerCaseSearchText) || rs.participantType().toLowerCase().contains(lowerCaseSearchText) || getLabel(bpObject).toLowerCase().contains(lowerCaseSearchText) || getType(bpObject).toLowerCase().contains(lowerCaseSearchText)) {
                pathwayObjectList.add(rs);
            }
        }
    }
    setData(pathwayObjectList);
    GuiUtils.flexResizeTableColumns(ownerTable);
}

Example 4 with Pathway

use of org.vcell.pathway.Pathway in project vcell by virtualcell.

the class PathwayReaderBiopax3 method addContentPathway.

private boolean addContentPathway(Pathway pathway, Element element, Element childElement) {
    if (addContentEntity(pathway, element, childElement)) {
        return true;
    }
    /**
     * BioSource organism
     * ArrayList<Interaction> pathwayComponentInteraction
     * ArrayList<Pathway> pathwayComponentPathway
     * ArrayList<PathwayStep> pathwayOrder
     */
    if (childElement.getName().equals("organism")) {
        pathway.setOrganism(addObjectBioSource(childElement));
        return true;
    } else if (childElement.getName().equals("pathwayOrder")) {
        pathway.getPathwayOrder().add(addObjectPathwayStep(childElement));
        return true;
    } else if (childElement.getName().equals("pathwayComponent")) {
        if (childElement.getChildren().size() == 0) {
            // if there are no children it must be a resource inside another object
            // we don't know yet whether it's Interaction or Pathway, we make a proxy for each
            // at the time when we solve the references we'll find out which is fake
            InteractionProxy proxyI = new InteractionProxy();
            addAttributes(proxyI, childElement);
            pathwayModel.add(proxyI);
            pathway.getPathwayComponentInteraction().add(proxyI);
            PathwayProxy proxyP = new PathwayProxy();
            addAttributes(proxyP, childElement);
            pathwayModel.add(proxyP);
            pathway.getPathwayComponentPathway().add(proxyP);
            return true;
        } else {
            // it's the real object declaration - could be an interaction or a pathway
            for (Object child : childElement.getChildren()) {
                if (child instanceof Element) {
                    if (((Element) child).getName().equals("Pathway")) {
                        Pathway thingie = addObjectPathway((Element) child);
                        pathway.getPathwayComponentPathway().add(thingie);
                        return true;
                    } else {
                        Interaction thingie = (Interaction) addObjectBioPaxObjectSubclass((Element) child);
                        if (thingie == null) {
                            return false;
                        } else {
                            pathway.getPathwayComponentInteraction().add(thingie);
                            return true;
                        }
                    }
                }
            }
        }
        return false;
    } else {
        return false;
    }
}

Example 5 with Pathway

use of org.vcell.pathway.Pathway in project vcell by virtualcell.

the class PathwayReaderBiopax3 method addObjectPathway.

// proxy thing done elsewhere
private Pathway addObjectPathway(Element element) {
    Pathway pathway = new Pathway();
    addAttributes(pathway, element);
    for (Object child : element.getChildren()) {
        if (child instanceof Element) {
            Element childElement = (Element) child;
            if (!addContentPathway(pathway, element, childElement)) {
                showUnexpected(childElement);
            }
        }
    }
    pathwayModel.add(pathway);
    return pathway;
}