Examples with ArchiveComponents org.jlibsedml.ArchiveComponents used on opensource projects

Example 1 with ArchiveComponents

use of org.jlibsedml.ArchiveComponents in project vcell by virtualcell.

the class XmlHelper method sedmlToBioModel.

public static VCDocument sedmlToBioModel(VCLogger transLogger, ExternalDocInfo externalDocInfo, SedML sedml, AbstractTask selectedTask) throws Exception {
    if (sedml.getModels().isEmpty()) {
        return null;
    }
    VCDocument doc = null;
    try {
        // extract the path only from the sedml file
        String fullPath = FileUtils.getFullPath(externalDocInfo.getFile().getAbsolutePath());
        // Namespace namespace = sedml.getNamespace();
        // iterate through all the elements and show them at the console
        List<org.jlibsedml.Model> mmm = sedml.getModels();
        for (Model mm : mmm) {
            System.out.println(mm.toString());
        }
        List<org.jlibsedml.Simulation> sss = sedml.getSimulations();
        for (org.jlibsedml.Simulation ss : sss) {
            System.out.println(ss.toString());
        }
        List<AbstractTask> ttt = sedml.getTasks();
        for (AbstractTask tt : ttt) {
            System.out.println(tt.toString());
        }
        List<DataGenerator> ddd = sedml.getDataGenerators();
        for (DataGenerator dd : ddd) {
            System.out.println(dd.toString());
        }
        List<Output> ooo = sedml.getOutputs();
        for (Output oo : ooo) {
            System.out.println(oo.toString());
        }
        KisaoTerm sedmlKisao = null;
        // this will become the vCell simulation
        org.jlibsedml.Simulation sedmlSimulation = null;
        // the "original" model referred to by the task
        org.jlibsedml.Model sedmlOriginalModel = null;
        String sedmlOriginalModelName = null;
        if (selectedTask == null) {
            // no task, just pick the Model and find its sbml file
            sedmlOriginalModelName = SEDMLUtil.getName(mmm.get(0));
        } else {
            if (selectedTask instanceof Task) {
                sedmlOriginalModel = sedml.getModelWithId(selectedTask.getModelReference());
                sedmlSimulation = sedml.getSimulation(selectedTask.getSimulationReference());
            } else if (selectedTask instanceof RepeatedTask) {
                RepeatedTask rt = (RepeatedTask) selectedTask;
                assert (rt.getSubTasks().size() == 1);
                // first (and only) subtask
                SubTask st = rt.getSubTasks().entrySet().iterator().next().getValue();
                String taskId = st.getTaskId();
                AbstractTask t = sedml.getTaskWithId(taskId);
                // get model and simulation from subtask
                sedmlOriginalModel = sedml.getModelWithId(t.getModelReference());
                sedmlSimulation = sedml.getSimulation(t.getSimulationReference());
            } else {
                throw new RuntimeException("Unexpected task " + selectedTask);
            }
            sedmlOriginalModelName = sedmlOriginalModel.getId();
            sedmlKisao = KisaoOntology.getInstance().getTermById(sedmlSimulation.getAlgorithm().getKisaoID());
        }
        // UniformTimeCourse [initialTime=0.0, numberOfPoints=1000, outputEndTime=1.0, outputStartTime=0.0,
        // Algorithm [kisaoID=KISAO:0000019], getId()=SimSlow]
        // identify the vCell solvers that would match best the sedml solver kisao id
        List<SolverDescription> solverDescriptions = new ArrayList<>();
        for (SolverDescription sd : SolverDescription.values()) {
            KisaoTerm solverKisaoTerm = KisaoOntology.getInstance().getTermById(sd.getKisao());
            if (solverKisaoTerm == null) {
                break;
            }
            boolean isExactlySame = solverKisaoTerm.equals(sedmlKisao);
            if (isExactlySame && !solverKisaoTerm.isObsolete()) {
                // we make a list with all the solvers that match the kisao
                solverDescriptions.add(sd);
            }
        }
        // from the list of vcell solvers that match the sedml kisao we select the ones that have a matching time step
        SolverDescription solverDescription = null;
        for (SolverDescription sd : solverDescriptions) {
            if (true) {
                solverDescription = sd;
                break;
            }
        }
        // find out everything else we need about the application we're going to use,
        // some of the info will be needed when we parse the sbml file
        boolean bSpatial = false;
        Application appType = Application.NETWORK_DETERMINISTIC;
        Set<SolverDescription.SolverFeature> sfList = solverDescription.getSupportedFeatures();
        for (SolverDescription.SolverFeature sf : sfList) {
            switch(sf) {
                case Feature_Rulebased:
                    appType = Application.RULE_BASED_STOCHASTIC;
                    break;
                case Feature_Stochastic:
                    appType = Application.NETWORK_STOCHASTIC;
                    break;
                case Feature_Deterministic:
                    appType = Application.NETWORK_DETERMINISTIC;
                    break;
                case Feature_Spatial:
                    bSpatial = true;
                    break;
                default:
                    break;
            }
        }
        // -------------------------------------------------------------------------------------------
        // extract bioModel name from sedx (or sedml) file
        String bioModelName = FileUtils.getBaseName(externalDocInfo.getFile().getAbsolutePath());
        // if we have repeated task, we ignore them, we just use the normal resolvers for archive and changes
        // once the application and simulation are built, we iterate through the repeated tasks and
        // add math overrides to the simulation for each repeated task
        ArchiveComponents ac = null;
        if (externalDocInfo.getFile().getPath().toLowerCase().endsWith("sedx") || externalDocInfo.getFile().getPath().toLowerCase().endsWith("omex")) {
            ac = Libsedml.readSEDMLArchive(new FileInputStream(externalDocInfo.getFile().getPath()));
        }
        ModelResolver resolver = new ModelResolver(sedml);
        if (ac != null) {
            resolver.add(new ArchiveModelResolver(ac));
        }
        resolver.add(new FileModelResolver());
        resolver.add(new RelativeFileModelResolver(fullPath));
        String newMdl = resolver.getModelString(sedmlOriginalModel);
        // sbmlSource with all the changes applied
        XMLSource sbmlSource = new XMLSource(newMdl);
        doc = XmlHelper.importSBML(transLogger, sbmlSource, bSpatial);
        BioModel bioModel = (BioModel) doc;
        bioModel.setName(bioModelName);
        // we already have an application loaded from the sbml file, with initial conditions and stuff
        // which may be not be suitable because the sedml kisao may need a different app type
        // so we do a "copy as" to the right type and then delete the original we loaded from the sbml file
        // the new application we're making from the old one
        SimulationContext newSimulationContext = null;
        if (bioModel.getSimulationContexts().length == 1) {
            SimulationContext oldSimulationContext = bioModel.getSimulationContext(0);
            newSimulationContext = SimulationContext.copySimulationContext(oldSimulationContext, sedmlOriginalModelName, bSpatial, appType);
            bioModel.removeSimulationContext(oldSimulationContext);
            bioModel.addSimulationContext(newSimulationContext);
        } else {
            // length == 0
            newSimulationContext = bioModel.addNewSimulationContext(sedmlOriginalModelName, appType);
        }
        // making the new vCell simulation based on the sedml simulation
        newSimulationContext.refreshDependencies();
        MathMappingCallback callback = new MathMappingCallbackTaskAdapter(null);
        newSimulationContext.refreshMathDescription(callback, NetworkGenerationRequirements.ComputeFullStandardTimeout);
        Simulation newSimulation = new Simulation(newSimulationContext.getMathDescription());
        newSimulation.setName(SEDMLUtil.getName(sedmlSimulation));
        // TODO: make sure that everything has proper names
        // we check the repeated tasks, if any, and add to the list of math overrides
        // if(selectedTask instanceof RepeatedTask) {
        // for(Change change : ((RepeatedTask) selectedTask).getChanges()) {
        // if(!(change instanceof SetValue)) {
        // throw new RuntimeException("Only 'SetValue' changes are supported for repeated tasks.");
        // }
        // SetValue setValue = (SetValue)change;
        // // TODO: extract target from XPath
        // // ......
        // //
        // String target = "s0";	// for now we just use a hardcoded thing
        // ConstantArraySpec cas;
        // Range range = ((RepeatedTask) selectedTask).getRange(setValue.getRangeReference());
        // if(range instanceof UniformRange) {
        // cas = ConstantArraySpec.createIntervalSpec(target, ((UniformRange) range).getStart(), ((UniformRange) range).getEnd(),
        // range.getNumElements(), ((UniformRange) range).getType() == UniformRange.UniformType.LOG ? true : false);
        // } else if(range instanceof VectorRange) {
        // //    				List<String> constants = new ArrayList<> ();
        // //    				for(int i=0; i<range.getNumElements(); i++) {
        // //    					constants.add(new Constant(i+"", new Expression(range.getElementAt(i))));
        // //    				}
        // //    				cas = ConstantArraySpec.createListSpec(target, constants);
        // 
        // } else {
        // throw new RuntimeException("Only 'Uniform Range' and 'Vector Range' are supported at this time.");
        // }
        // 
        // }
        // }
        // we identify the type of sedml simulation (uniform time course, etc)
        // and set the vCell simulation parameters accordingly
        SolverTaskDescription simTaskDesc = newSimulation.getSolverTaskDescription();
        TimeBounds timeBounds = new TimeBounds();
        TimeStep timeStep = new TimeStep();
        double outputTimeStep = 0.1;
        if (sedmlSimulation instanceof UniformTimeCourse) {
            // we translate initial time to zero, we provide output for the duration of the simulation
            // because we can't select just an interval the way the SEDML simulation can
            double initialTime = ((UniformTimeCourse) sedmlSimulation).getInitialTime();
            double outputStartTime = ((UniformTimeCourse) sedmlSimulation).getOutputStartTime();
            double outputEndTime = ((UniformTimeCourse) sedmlSimulation).getOutputEndTime();
            double outputNumberOfPoints = ((UniformTimeCourse) sedmlSimulation).getNumberOfPoints();
            outputTimeStep = (outputEndTime - outputStartTime) / outputNumberOfPoints;
            timeBounds = new TimeBounds(0, outputEndTime - initialTime);
        } else if (sedmlSimulation instanceof OneStep) {
        // for anything other than UniformTimeCourse we just ignore
        } else if (sedmlSimulation instanceof SteadyState) {
        } else {
        }
        OutputTimeSpec outputTimeSpec = new UniformOutputTimeSpec(outputTimeStep);
        simTaskDesc.setTimeBounds(timeBounds);
        simTaskDesc.setTimeStep(timeStep);
        simTaskDesc.setOutputTimeSpec(outputTimeSpec);
        newSimulation.setSolverTaskDescription(simTaskDesc);
        bioModel.addSimulation(newSimulation);
        newSimulation.refreshDependencies();
    } catch (Exception e) {
        e.printStackTrace();
        throw new RuntimeException("Unable to initialize bioModel for the given selection.");
    }
    return doc;
}

Example 2 with ArchiveComponents

use of org.jlibsedml.ArchiveComponents in project vcell by virtualcell.

the class ClientRequestManager method openAfterChecking.

private void openAfterChecking(VCDocumentInfo documentInfo, final TopLevelWindowManager requester, final boolean inNewWindow) {
    final String DOCUMENT_INFO = "documentInfo";
    final String SEDML_TASK = "SedMLTask";
    final String SEDML_MODELS = "SedMLModels";
    final String BNG_UNIT_SYSTEM = "bngUnitSystem";
    final String BMDB_DEFAULT_APPLICATION = "Deterministic";
    /* asynchronous and not blocking any window */
    bOpening = true;
    Hashtable<String, Object> hashTable = new Hashtable<String, Object>();
    // may want to insert corrected VCDocumentInfo later if our import debugger
    // corrects it (BNGL Debugger).
    hashTable.put(DOCUMENT_INFO, documentInfo);
    hashTable.put("isBMDB", false);
    hashTable.put("isSEDML", false);
    // start a thread that gets it and updates the GUI by creating a new document
    // desktop
    String taskName = null;
    if (documentInfo instanceof ExternalDocInfo) {
        taskName = "Importing document";
        ExternalDocInfo externalDocInfo = (ExternalDocInfo) documentInfo;
        File file = externalDocInfo.getFile();
        if (file != null && !file.getName().isEmpty() && file.getName().endsWith("bngl")) {
            BngUnitSystem bngUnitSystem = new BngUnitSystem(BngUnitOrigin.DEFAULT);
            String fileText;
            String originalFileText;
            try {
                fileText = BeanUtils.readBytesFromFile(file, null);
                originalFileText = new String(fileText);
            } catch (IOException e1) {
                e1.printStackTrace();
                DialogUtils.showErrorDialog(requester.getComponent(), "<html>Error reading file " + file.getPath() + "</html>");
                return;
            }
            Reader reader = externalDocInfo.getReader();
            boolean bException = true;
            while (bException) {
                try {
                    BioModel bioModel = createDefaultBioModelDocument(bngUnitSystem);
                    boolean bStochastic = true;
                    boolean bRuleBased = true;
                    SimulationContext ruleBasedSimContext = bioModel.addNewSimulationContext("temp NFSim app", SimulationContext.Application.RULE_BASED_STOCHASTIC);
                    List<SimulationContext> appList = new ArrayList<SimulationContext>();
                    appList.add(ruleBasedSimContext);
                    RbmModelContainer rbmModelContainer = bioModel.getModel().getRbmModelContainer();
                    RbmUtils.reactionRuleLabelIndex = 0;
                    RbmUtils.reactionRuleNames.clear();
                    ASTModel astModel = RbmUtils.importBnglFile(reader);
                    // for now, hasUnitSystem() always returns false
                    if (astModel.hasUnitSystem()) {
                        bngUnitSystem = astModel.getUnitSystem();
                    }
                    if (astModel.hasCompartments()) {
                        Structure struct = bioModel.getModel().getStructure(0);
                        if (struct != null) {
                            bioModel.getModel().removeStructure(struct);
                        }
                    }
                    BnglObjectConstructionVisitor constructionVisitor = null;
                    if (!astModel.hasMolecularDefinitions()) {
                        System.out.println("Molecular Definition Block missing.");
                        constructionVisitor = new BnglObjectConstructionVisitor(bioModel.getModel(), appList, bngUnitSystem, false);
                    } else {
                        constructionVisitor = new BnglObjectConstructionVisitor(bioModel.getModel(), appList, bngUnitSystem, true);
                    }
                    astModel.jjtAccept(constructionVisitor, rbmModelContainer);
                    bException = false;
                } catch (final Exception e) {
                    e.printStackTrace(System.out);
                    BNGLDebuggerPanel panel = new BNGLDebuggerPanel(fileText, e);
                    int oKCancel = DialogUtils.showComponentOKCancelDialog(requester.getComponent(), panel, "Bngl Debugger: " + file.getName());
                    if (oKCancel == JOptionPane.CANCEL_OPTION || oKCancel == JOptionPane.DEFAULT_OPTION) {
                        throw new UserCancelException("Canceling Import");
                    }
                    // inserting <potentially> corrected DocumentInfo
                    fileText = panel.getText();
                    externalDocInfo = new ExternalDocInfo(panel.getText());
                    reader = externalDocInfo.getReader();
                    hashTable.put(DOCUMENT_INFO, externalDocInfo);
                }
            }
            if (!originalFileText.equals(fileText)) {
                // file has been modified
                String message = "Importing <b>" + file.getName() + "</b> into vCell. <br>Overwrite the file on the disk?<br>";
                message = "<html>" + message + "</html>";
                Object[] options = { "Overwrite and Import", "Import Only", "Cancel" };
                int returnCode = JOptionPane.showOptionDialog(requester.getComponent(), message, "Bngl Debugger", JOptionPane.YES_NO_CANCEL_OPTION, JOptionPane.QUESTION_MESSAGE, null, options, options[2]);
                if (returnCode == JOptionPane.YES_OPTION) {
                    try {
                        FileWriter fw = new FileWriter(file);
                        fw.write(fileText);
                        fw.close();
                    } catch (IOException e) {
                        e.printStackTrace();
                    }
                } else if (returnCode == JOptionPane.CANCEL_OPTION || returnCode == JOptionPane.CLOSED_OPTION) {
                    return;
                }
            }
            if (!(bngUnitSystem.getOrigin() == BngUnitOrigin.PARSER)) {
                BNGLUnitsPanel panel = new BNGLUnitsPanel(bngUnitSystem);
                int oKCancel = DialogUtils.showComponentOKCancelDialog(requester.getComponent(), panel, " Bngl Units Selector", null, false);
                if (oKCancel == JOptionPane.CANCEL_OPTION || oKCancel == JOptionPane.DEFAULT_OPTION) {
                    // TODO: or do nothing and continue with default values?
                    return;
                } else {
                    bngUnitSystem = panel.getUnits();
                }
            }
            hashTable.put(BNG_UNIT_SYSTEM, bngUnitSystem);
        } else if (file != null && !file.getName().isEmpty() && file.getName().toLowerCase().endsWith(".sedml")) {
            try {
                XMLSource xmlSource = externalDocInfo.createXMLSource();
                File sedmlFile = xmlSource.getXmlFile();
                SedML sedml = Libsedml.readDocument(sedmlFile).getSedMLModel();
                if (sedml == null || sedml.getModels().isEmpty()) {
                    return;
                }
                // AbstractTask chosenTask = SEDMLChooserPanel.chooseTask(sedml, requester.getComponent(),
                // file.getName());
                List<SedML> sedmls = new ArrayList<>();
                sedmls.add(sedml);
                hashTable.put(SEDML_MODELS, sedmls);
            // hashTable.put(SEDML_TASK, chosenTask);
            } catch (Exception e) {
                e.printStackTrace();
                throw new RuntimeException("failed to read document: " + e.getMessage(), e);
            }
        } else if (file != null && !file.getName().isEmpty() && (file.getName().toLowerCase().endsWith(".sedx") || file.getName().toLowerCase().endsWith(".omex"))) {
            try {
                ArchiveComponents ac = null;
                ac = Libsedml.readSEDMLArchive(new FileInputStream(file));
                List<SEDMLDocument> docs = ac.getSedmlDocuments();
                List<SedML> sedmls = new ArrayList<>();
                for (SEDMLDocument doc : docs) {
                    SedML sedml = doc.getSedMLModel();
                    if (sedml == null) {
                        throw new RuntimeException("Failed importing " + file.getName());
                    }
                    if (sedml.getModels().isEmpty()) {
                        throw new RuntimeException("Unable to find any model in " + file.getName());
                    }
                    sedmls.add(sedml);
                }
                // AbstractTask chosenTask = SEDMLChooserPanel.chooseTask(sedml, requester.getComponent(),
                // file.getName());
                hashTable.put(SEDML_MODELS, sedmls);
            // hashTable.put(SEDML_TASK, chosenTask);
            } catch (Exception e) {
                e.printStackTrace();
                throw new RuntimeException("failed to read archive: " + e.getMessage(), e);
            }
        }
    } else {
        taskName = "Loading document '" + documentInfo.getVersion().getName() + "' from database";
    }
    AsynchClientTask task0 = new AsynchClientTask(taskName, AsynchClientTask.TASKTYPE_SWING_BLOCKING) {

        public void run(Hashtable<String, Object> hashTable) throws Exception {
            if (!inNewWindow) {
                // request was to replace the document in an existing window
                getMdiManager().blockWindow(requester.getManagerID());
            }
        }
    };
    AsynchClientTask task1 = new AsynchClientTask(taskName, AsynchClientTask.TASKTYPE_NONSWING_BLOCKING) {

        @Override
        public void run(Hashtable<String, Object> hashTable) throws Exception {
            VCDocument doc = null;
            List<VCDocument> docs = new ArrayList<>();
            boolean isBMDB = false;
            boolean isSEDML = false;
            VCDocumentInfo documentInfo = (VCDocumentInfo) hashTable.get(DOCUMENT_INFO);
            if (documentInfo instanceof BioModelInfo) {
                BioModelInfo bmi = (BioModelInfo) documentInfo;
                doc = getDocumentManager().getBioModel(bmi);
            } else if (documentInfo instanceof MathModelInfo) {
                MathModelInfo mmi = (MathModelInfo) documentInfo;
                doc = getDocumentManager().getMathModel(mmi);
            } else if (documentInfo instanceof GeometryInfo) {
                GeometryInfo gmi = (GeometryInfo) documentInfo;
                doc = getDocumentManager().getGeometry(gmi);
            } else if (documentInfo instanceof ExternalDocInfo) {
                ExternalDocInfo externalDocInfo = (ExternalDocInfo) documentInfo;
                File file = externalDocInfo.getFile();
                if (file != null && !file.getName().isEmpty() && (file.getName().toLowerCase().endsWith(".sedx") || file.getName().toLowerCase().endsWith(".omex"))) {
                    TranslationLogger transLogger = new TranslationLogger(requester);
                    // iterate through one or more SEDML objects
                    List<SedML> sedmls = (List<SedML>) hashTable.get(SEDML_MODELS);
                    for (SedML sedml : sedmls) {
                        // default to import all tasks
                        List<VCDocument> vcdocs = XmlHelper.sedmlToBioModel(transLogger, externalDocInfo, sedml, null, null, false);
                        for (VCDocument vcdoc : vcdocs) {
                            docs.add(vcdoc);
                        }
                    }
                    // treat the same since OMEX is just and archive with SED-ML file(s)
                    isSEDML = true;
                } else if (!externalDocInfo.isXML()) {
                    if (hashTable.containsKey(BNG_UNIT_SYSTEM)) {
                        // not XML, look for BNGL etc.
                        // we use the BngUnitSystem already created during the 1st pass
                        BngUnitSystem bngUnitSystem = (BngUnitSystem) hashTable.get(BNG_UNIT_SYSTEM);
                        BioModel bioModel = createDefaultBioModelDocument(bngUnitSystem);
                        SimulationContext ruleBasedSimContext = bioModel.addNewSimulationContext("NFSim app", SimulationContext.Application.RULE_BASED_STOCHASTIC);
                        SimulationContext odeSimContext = bioModel.addNewSimulationContext("BioNetGen app", SimulationContext.Application.NETWORK_DETERMINISTIC);
                        List<SimulationContext> appList = new ArrayList<SimulationContext>();
                        appList.add(ruleBasedSimContext);
                        appList.add(odeSimContext);
                        // set convention for initial conditions in generated application for seed
                        // species (concentration or count)
                        ruleBasedSimContext.setUsingConcentration(bngUnitSystem.isConcentration());
                        odeSimContext.setUsingConcentration(bngUnitSystem.isConcentration());
                        RbmModelContainer rbmModelContainer = bioModel.getModel().getRbmModelContainer();
                        RbmUtils.reactionRuleLabelIndex = 0;
                        RbmUtils.reactionRuleNames.clear();
                        Reader reader = externalDocInfo.getReader();
                        ASTModel astModel = RbmUtils.importBnglFile(reader);
                        if (bioModel.getModel() != null && bioModel.getModel().getVcMetaData() != null) {
                            VCMetaData vcMetaData = bioModel.getModel().getVcMetaData();
                            vcMetaData.setFreeTextAnnotation(bioModel, astModel.getProlog());
                        }
                        if (astModel.hasCompartments()) {
                            Structure struct = bioModel.getModel().getStructure(0);
                            if (struct != null) {
                                bioModel.getModel().removeStructure(struct);
                            }
                        }
                        BnglObjectConstructionVisitor constructionVisitor = null;
                        if (!astModel.hasMolecularDefinitions()) {
                            System.out.println("Molecular Definition Block missing. Extracting it from Species, Reactions, Obserbables.");
                            constructionVisitor = new BnglObjectConstructionVisitor(bioModel.getModel(), appList, bngUnitSystem, false);
                        } else {
                            constructionVisitor = new BnglObjectConstructionVisitor(bioModel.getModel(), appList, bngUnitSystem, true);
                        }
                        // we'll convert the kinetic parameters to BngUnitSystem inside the
                        // visit(ASTKineticsParameter...)
                        astModel.jjtAccept(constructionVisitor, rbmModelContainer);
                        // set the volume in the newly created application to
                        // BngUnitSystem.bnglModelVolume
                        // TODO: set the right values if we import compartments from the bngl file!
                        // if(!bngUnitSystem.isConcentration()) {
                        Expression sizeExpression = new Expression(bngUnitSystem.getVolume());
                        ruleBasedSimContext.getGeometryContext().getStructureMapping(0).getSizeParameter().setExpression(sizeExpression);
                        odeSimContext.getGeometryContext().getStructureMapping(0).getSizeParameter().setExpression(sizeExpression);
                        // }
                        // we remove the NFSim application if any seed species is clamped because NFSim
                        // doesn't know what to do with it
                        boolean bClamped = false;
                        for (SpeciesContextSpec scs : ruleBasedSimContext.getReactionContext().getSpeciesContextSpecs()) {
                            if (scs.isConstant()) {
                                bClamped = true;
                                break;
                            }
                        }
                        if (bClamped) {
                            bioModel.removeSimulationContext(ruleBasedSimContext);
                        }
                        // // TODO: DON'T delete this code
                        // // the code below is needed if we also want to create simulations, example for 1 rule based simulation
                        // // it is rule-based so it wont have to flatten, should be fast.
                        // MathMappingCallback callback = new MathMappingCallbackTaskAdapter(getClientTaskStatusSupport());
                        // NetworkGenerationRequirements networkGenerationRequirements = null; // network generation should not be executed.
                        // ruleBasedSimContext.refreshMathDescription(callback,networkGenerationRequirements);
                        // Simulation sim = ruleBasedSimContext.addNewSimulation(SimulationOwner.DEFAULT_SIM_NAME_PREFIX,callback,networkGenerationRequirements);
                        doc = bioModel;
                    }
                } else {
                    // is XML
                    try (TranslationLogger transLogger = new TranslationLogger(requester)) {
                        XMLSource xmlSource = externalDocInfo.createXMLSource();
                        org.jdom.Element rootElement = xmlSource.getXmlDoc().getRootElement();
                        String xmlType = rootElement.getName();
                        String modelXmlType = null;
                        if (xmlType.equals(XMLTags.VcmlRootNodeTag)) {
                            // For now, assuming that <vcml> element has only one child (biomodel, mathmodel
                            // or geometry).
                            // Will deal with multiple children of <vcml> Element when we get to model
                            // composition.
                            @SuppressWarnings("unchecked") List<Element> childElementList = rootElement.getChildren();
                            // assuming first child is the biomodel,
                            Element modelElement = childElementList.get(0);
                            // mathmodel or geometry.
                            modelXmlType = modelElement.getName();
                        }
                        if (xmlType.equals(XMLTags.BioModelTag) || (xmlType.equals(XMLTags.VcmlRootNodeTag) && modelXmlType.equals(XMLTags.BioModelTag))) {
                            doc = XmlHelper.XMLToBioModel(xmlSource);
                        } else if (xmlType.equals(XMLTags.MathModelTag) || (xmlType.equals(XMLTags.VcmlRootNodeTag) && modelXmlType.equals(XMLTags.MathModelTag))) {
                            doc = XmlHelper.XMLToMathModel(xmlSource);
                        } else if (xmlType.equals(XMLTags.GeometryTag) || (xmlType.equals(XMLTags.VcmlRootNodeTag) && modelXmlType.equals(XMLTags.GeometryTag))) {
                            doc = XmlHelper.XMLToGeometry(xmlSource);
                        } else if (xmlType.equals(XMLTags.SbmlRootNodeTag)) {
                            Namespace namespace = rootElement.getNamespace(XMLTags.SBML_SPATIAL_NS_PREFIX);
                            isBMDB = externalDocInfo.isBioModelsNet();
                            boolean bIsSpatial = (namespace == null) ? false : true;
                            doc = XmlHelper.importSBML(transLogger, xmlSource, bIsSpatial);
                        } else if (xmlType.equals(XMLTags.CellmlRootNodeTag)) {
                            if (requester instanceof BioModelWindowManager) {
                                doc = XmlHelper.importBioCellML(transLogger, xmlSource);
                            } else {
                                doc = XmlHelper.importMathCellML(transLogger, xmlSource);
                            }
                        } else if (xmlType.equals(MicroscopyXMLTags.FRAPStudyTag)) {
                            doc = VFrapXmlHelper.VFRAPToBioModel(hashTable, xmlSource, getDocumentManager(), requester);
                        } else if (xmlType.equals(XMLTags.SedMLTypeTag)) {
                            // we know it is a single SedML since it is an actual XML source
                            List<SedML> sedmls = (List<SedML>) hashTable.get(SEDML_MODELS);
                            SedML sedml = sedmls.get(0);
                            // default to import all tasks
                            docs = XmlHelper.sedmlToBioModel(transLogger, externalDocInfo, sedml, null, externalDocInfo.getFile().getAbsolutePath(), false);
                            isSEDML = true;
                        } else {
                            // unknown XML format
                            throw new RuntimeException("unsupported XML format, first element tag is <" + rootElement.getName() + ">");
                        }
                        if (externalDocInfo.getDefaultName() != null) {
                            doc.setName(externalDocInfo.getDefaultName());
                        }
                    }
                }
                if (doc == null && docs == null) {
                    File f = externalDocInfo.getFile();
                    if (f != null) {
                        throw new RuntimeException("Unable to determine type of file " + f.getCanonicalPath());
                    }
                    throw new ProgrammingException();
                }
            }
            // create biopax objects using annotation
            if (doc instanceof BioModel) {
                BioModel bioModel = (BioModel) doc;
                try {
                    bioModel.getVCMetaData().createBioPaxObjects(bioModel);
                } catch (Exception e) {
                    e.printStackTrace();
                }
            }
            requester.prepareDocumentToLoad(doc, inNewWindow);
            hashTable.put("isBMDB", isBMDB);
            hashTable.put("isSEDML", isSEDML);
            if (!isSEDML) {
                hashTable.put("doc", doc);
            } else {
                hashTable.put("docs", docs);
            }
        }
    };
    AsynchClientTask task2 = new AsynchClientTask("Showing document", AsynchClientTask.TASKTYPE_SWING_BLOCKING, false, false) {

        @Override
        public void run(Hashtable<String, Object> hashTable) throws Exception {
            try {
                Throwable exc = (Throwable) hashTable.get(ClientTaskDispatcher.TASK_ABORTED_BY_ERROR);
                if (exc == null) {
                    boolean isSEDML = (boolean) hashTable.get("isSEDML");
                    if (isSEDML) {
                        List<VCDocument> docs = (List<VCDocument>) hashTable.get("docs");
                        List<DocumentWindowManager> windowManagers = new ArrayList<DocumentWindowManager>();
                        for (VCDocument doc : docs) {
                            DocumentWindowManager windowManager = createDocumentWindowManager(doc);
                            getMdiManager().createNewDocumentWindow(windowManager);
                            windowManagers.add(windowManager);
                        }
                        hashTable.put("managers", windowManagers);
                        hashTable.put("docs", docs);
                    } else {
                        VCDocument doc = (VCDocument) hashTable.get("doc");
                        DocumentWindowManager windowManager = null;
                        if (inNewWindow) {
                            windowManager = createDocumentWindowManager(doc);
                            // request was to create a new top-level window with this doc
                            getMdiManager().createNewDocumentWindow(windowManager);
                        } else {
                            // request was to replace the document in an existing window
                            windowManager = (DocumentWindowManager) requester;
                            getMdiManager().setCanonicalTitle(requester.getManagerID());
                            windowManager.resetDocument(doc);
                        }
                        hashTable.put(WIN_MGR_KEY, windowManager);
                        hashTable.put("doc", doc);
                    }
                }
            } catch (Exception ex) {
                ex.printStackTrace();
            // TODO: check why getMdiManager().createNewDocumentWindow(windowManager) fails sometimes
            } finally {
                if (!inNewWindow) {
                    getMdiManager().unBlockWindow(requester.getManagerID());
                }
                bOpening = false;
            }
        }
    };
    AsynchClientTask task3 = new AsynchClientTask("Special Layout", AsynchClientTask.TASKTYPE_SWING_BLOCKING, false, false) {

        @Override
        public void run(Hashtable<String, Object> hashTable) throws Exception {
            if (documentInfo instanceof ExternalDocInfo) {
                ExternalDocInfo externalDocInfo = (ExternalDocInfo) documentInfo;
                boolean isSEDML = (boolean) hashTable.get("isSEDML");
                if (externalDocInfo.isBioModelsNet() || externalDocInfo.isFromXmlFile() || !isSEDML) {
                    DocumentWindowManager windowManager = (DocumentWindowManager) hashTable.get(WIN_MGR_KEY);
                    if (windowManager instanceof BioModelWindowManager) {
                        ((BioModelWindowManager) windowManager).specialLayout();
                    }
                }
                if (isSEDML) {
                    List<DocumentWindowManager> windowManagers = (List<DocumentWindowManager>) hashTable.get("managers");
                    if (windowManagers != null) {
                        for (DocumentWindowManager manager : windowManagers) {
                            ((BioModelWindowManager) manager).specialLayout();
                        }
                    }
                }
            }
        }
    };
    AsynchClientTask task4 = new AsynchClientTaskFunction(ClientRequestManager::setWindowFocus, "Set window focus", AsynchClientTask.TASKTYPE_SWING_BLOCKING, false, false);
    AsynchClientTask task6 = new AsynchClientTask("Renaming, please wait...", // TASKTYPE_NONSWING_BLOCKING
    AsynchClientTask.TASKTYPE_NONSWING_BLOCKING, // TASKTYPE_NONSWING_BLOCKING
    false, // TASKTYPE_NONSWING_BLOCKING
    false) {

        @Override
        public void run(Hashtable<String, Object> hashTable) throws Exception {
            VCDocument doc = (VCDocument) hashTable.get("doc");
            if (!(doc instanceof BioModel)) {
                return;
            }
            boolean isBMDB = (boolean) hashTable.get("isBMDB");
            if (documentInfo instanceof ExternalDocInfo) {
                if (isBMDB) {
                    idToNameConversion(doc);
                }
            }
            if (isBMDB) {
                BioModel bioModel = (BioModel) doc;
                SimulationContext simulationContext = bioModel.getSimulationContext(0);
                simulationContext.setName(BMDB_DEFAULT_APPLICATION);
                MathMappingCallback callback = new MathMappingCallback() {

                    @Override
                    public void setProgressFraction(float fractionDone) {
                    }

                    @Override
                    public void setMessage(String message) {
                    }

                    @Override
                    public boolean isInterrupted() {
                        return false;
                    }
                };
                MathMapping mathMapping = simulationContext.createNewMathMapping(callback, NetworkGenerationRequirements.ComputeFullNoTimeout);
                MathDescription mathDesc = null;
                try {
                    mathDesc = mathMapping.getMathDescription(callback);
                    simulationContext.setMathDescription(mathDesc);
                    Simulation sim = new Simulation(mathDesc);
                    sim.setName(simulationContext.getBioModel().getFreeSimulationName());
                    simulationContext.addSimulation(sim);
                    bioModel.refreshDependencies();
                } catch (MappingException | MathException | MatrixException | ExpressionException | ModelException e1) {
                    e1.printStackTrace();
                }
                hashTable.put("doc", doc);
            }
        }
    };
    ClientTaskDispatcher.dispatch(requester.getComponent(), hashTable, new AsynchClientTask[] { task0, task1, task6, task2, task3, task4 }, false);
}

Example 3 with ArchiveComponents

use of org.jlibsedml.ArchiveComponents in project vcell by virtualcell.

the class StandaloneSEDMLTest method doit.

public static void doit(File archiveFile) throws Exception {
    ArchiveComponents ac = null;
    ac = Libsedml.readSEDMLArchive(new FileInputStream(archiveFile));
    SEDMLDocument sedmlDoc = ac.getSedmlDocuments().get(0);
    SedML sedml = sedmlDoc.getSedMLModel();
    if (sedml == null || sedml.getModels().isEmpty()) {
        throw new RuntimeException("sedml null or empty");
    }
    ModelResolver resolver = new ModelResolver(sedml);
    // resolver.add(new FileModelResolver());
    resolver.add(new ArchiveModelResolver(ac));
    resolver.add(new BioModelsModelsRetriever());
    resolver.add(new URLResourceRetriever());
    // resolver.add(new RelativeFileModelResolver(FileUtils.getFullPath(archiveFile.getAbsolutePath())));
    // 
    // iterate through all the elements and show them at the console
    // 
    List<org.jlibsedml.Model> mmm = sedml.getModels();
    for (Model mm : mmm) {
        System.out.println(mm.toString());
    }
    List<org.jlibsedml.Simulation> sss = sedml.getSimulations();
    for (org.jlibsedml.Simulation ss : sss) {
        System.out.println(ss.toString());
    }
    List<AbstractTask> ttt = sedml.getTasks();
    for (AbstractTask tt : ttt) {
        System.out.println(tt.toString());
    }
    List<DataGenerator> ddd = sedml.getDataGenerators();
    for (DataGenerator dd : ddd) {
        System.out.println(dd.toString());
    }
    List<Output> ooo = sedml.getOutputs();
    for (Output oo : ooo) {
        System.out.println(oo.toString());
    }
    // 
    // extract models referenced in tasks.
    // 
    KisaoOntology kisaoInstance = KisaoOntology.getInstance();
    // HashMap<String,Model> flattenedModels = new HashMap<String, Model>();
    List<AbstractTask> taskList = sedml.getTasks();
    for (AbstractTask task : taskList) {
        String modelReference = task.getModelReference();
        org.jlibsedml.Model sedmlOriginalModel = sedml.getModelWithId(modelReference);
        String sbmlModelString = resolver.getModelString(sedmlOriginalModel);
        // sbmlSource with all the changes applied
        XMLSource sbmlSource = new XMLSource(sbmlModelString);
        org.jlibsedml.Simulation sedmlSimulation = sedml.getSimulation(task.getSimulationReference());
        Algorithm algorithm = sedmlSimulation.getAlgorithm();
        KisaoTerm sedmlKisao = kisaoInstance.getTermById(algorithm.getKisaoID());
        // 
        // try to find a VCell solverDescription to match the Kisao term
        // 
        // UniformTimeCourse [initialTime=0.0, numberOfPoints=1000, outputEndTime=1.0, outputStartTime=0.0,
        // Algorithm [kisaoID=KISAO:0000019], getId()=SimSlow]
        // identify the vCell solvers that would match best the sedml solver kisao id
        List<SolverDescription> solverDescriptions = new ArrayList<>();
        for (SolverDescription sd : SolverDescription.values()) {
            KisaoTerm solverKisaoTerm = kisaoInstance.getTermById(sd.getKisao());
            if (solverKisaoTerm == null) {
                break;
            }
            boolean isExactlySame = solverKisaoTerm.equals(sedmlKisao);
            if (isExactlySame && !solverKisaoTerm.isObsolete()) {
                // we make a list with all the solvers that match the kisao
                solverDescriptions.add(sd);
            }
        }
        if (solverDescriptions.isEmpty()) {
            throw new RuntimeException("cannot find the solverDescription with exact match for Kisao term '" + sedmlKisao + "'");
        }
        // choose first one
        SolverDescription solverDescription = solverDescriptions.get(0);
        // find out everything else we need about the application we're going to use,
        // some of the info will be needed when we parse the sbml file
        boolean bSpatial = false;
        Application appType = Application.NETWORK_DETERMINISTIC;
        Set<SolverDescription.SolverFeature> sfList = solverDescription.getSupportedFeatures();
        for (SolverDescription.SolverFeature sf : sfList) {
            switch(sf) {
                case Feature_Rulebased:
                    appType = Application.RULE_BASED_STOCHASTIC;
                    break;
                case Feature_Stochastic:
                    appType = Application.NETWORK_STOCHASTIC;
                    break;
                case Feature_Deterministic:
                    appType = Application.NETWORK_DETERMINISTIC;
                    break;
                case Feature_Spatial:
                    bSpatial = true;
                    break;
                default:
                    break;
            }
        }
        BioModel bioModel = (BioModel) XmlHelper.importSBML(transLogger, sbmlSource, bSpatial);
        // 
        // we already have an application loaded from the sbml file, with initial conditions and stuff
        // which may be not be suitable because the sedml kisao may need a different app type
        // so we do a "copy as" to the right type and then delete the original we loaded from the sbml file
        // 
        // the new application we're making from the old one
        SimulationContext newSimulationContext = null;
        if (bioModel.getSimulationContexts().length == 1) {
            SimulationContext oldSimulationContext = bioModel.getSimulationContext(0);
            String newSCName = bioModel.getFreeSimulationContextName();
            newSimulationContext = SimulationContext.copySimulationContext(oldSimulationContext, newSCName, bSpatial, appType);
            bioModel.addSimulationContext(newSimulationContext);
            bioModel.removeSimulationContext(oldSimulationContext);
        } else {
            newSimulationContext = bioModel.addNewSimulationContext("App1", appType);
        }
        // 
        // making the new vCell simulation based on the sedml simulation
        // 
        newSimulationContext.refreshDependencies();
        MathMappingCallback callback = new MathMappingCallbackTaskAdapter(progressListener);
        newSimulationContext.refreshMathDescription(callback, NetworkGenerationRequirements.ComputeFullStandardTimeout);
        Simulation newSimulation = new Simulation(newSimulationContext.getMathDescription());
        newSimulation.setName(sedmlSimulation.getName());
        bioModel.addSimulation(newSimulation);
        // and set the vCell simulation parameters accordingly
        if (sedmlSimulation instanceof UniformTimeCourse) {
        } else if (sedmlSimulation instanceof OneStep) {
        } else if (sedmlSimulation instanceof SteadyState) {
        } else {
        }
        System.out.println(XmlHelper.bioModelToXML(bioModel));
    }
}

Example 4 with ArchiveComponents

use of org.jlibsedml.ArchiveComponents in project vcell by virtualcell.

the class XmlHelper method sedmlToBioModel.

public static List<VCDocument> sedmlToBioModel(VCLogger transLogger, ExternalDocInfo externalDocInfo, SedML sedml, List<AbstractTask> tasks, String sedmlFileLocation, boolean exactMatchOnly) throws Exception {
    if (sedml.getModels().isEmpty()) {
        throw new Exception("No models found in SED-ML document");
    }
    try {
        // iterate through all the elements and show them at the console
        List<org.jlibsedml.Model> mmm = sedml.getModels();
        for (Model mm : mmm) {
            System.out.println(mm.toString());
        }
        List<org.jlibsedml.Simulation> sss = sedml.getSimulations();
        for (org.jlibsedml.Simulation ss : sss) {
            System.out.println(ss.toString());
        }
        List<AbstractTask> ttt = sedml.getTasks();
        if (ttt.isEmpty()) {
            throw new Exception("No tasks found in SED-ML document");
        }
        for (AbstractTask tt : ttt) {
            System.out.println(tt.toString());
        }
        List<DataGenerator> ddd = sedml.getDataGenerators();
        for (DataGenerator dd : ddd) {
            System.out.println(dd.toString());
        }
        List<Output> ooo = sedml.getOutputs();
        for (Output oo : ooo) {
            System.out.println(oo.toString());
        }
        if (ooo.isEmpty()) {
            System.err.println("List of outputs cannot be empty!");
        }
        if (tasks == null || tasks.isEmpty()) {
            // no task selection, we'll import all that we find in the SED-ML
            tasks = sedml.getTasks();
        }
        // We need to make a separate BioModel for each SED-ML model
        // We will parse all tasks and create Simulations for each in the BioModel(s) corresponding to the model referenced by the tasks
        List<VCDocument> docs = new ArrayList<VCDocument>();
        // extract bioModel name from sedx (or sedml) file
        String bioModelBaseName = FileUtils.getBaseName(externalDocInfo.getFile().getAbsolutePath());
        String kisaoID = null;
        // this will become the vCell simulation
        org.jlibsedml.Simulation sedmlSimulation = null;
        // the "original" model referred to by the task
        org.jlibsedml.Model sedmlOriginalModel = null;
        // this will be used in the BioModel name
        String sedmlOriginalModelName = null;
        // can be sbml or vcml
        String sedmlOriginalModelLanguage = null;
        ArchiveComponents ac = null;
        if (externalDocInfo.getFile().getPath().toLowerCase().endsWith("sedx") || externalDocInfo.getFile().getPath().toLowerCase().endsWith("omex")) {
            ac = Libsedml.readSEDMLArchive(new FileInputStream(externalDocInfo.getFile().getPath()));
        }
        ModelResolver resolver = new ModelResolver(sedml);
        if (ac != null) {
            resolver.add(new ArchiveModelResolver(ac));
        }
        resolver.add(new FileModelResolver());
        if (sedmlFileLocation != null) {
            File sedmlFile = new File(sedmlFileLocation);
            String sedmlRelativePrefix = sedmlFile.getParent() + File.separator;
            if (sedmlRelativePrefix != null) {
                resolver.add(new RelativeFileModelResolver(sedmlRelativePrefix));
            }
        }
        for (AbstractTask selectedTask : tasks) {
            if (selectedTask instanceof Task) {
                sedmlOriginalModel = sedml.getModelWithId(selectedTask.getModelReference());
                sedmlSimulation = sedml.getSimulation(selectedTask.getSimulationReference());
            } else if (selectedTask instanceof RepeatedTask) {
                System.err.println("RepeatedTask not supported yet, task " + SEDMLUtil.getName(selectedTask) + " is being skipped");
                continue;
            // TODO the below is unfinished code
            // RepeatedTask rt = (RepeatedTask)selectedTask;
            // assert(rt.getSubTasks().size() == 1);
            // SubTask st = rt.getSubTasks().entrySet().iterator().next().getValue();		// first (and only) subtask
            // String taskId = st.getTaskId();
            // AbstractTask t = sedml.getTaskWithId(taskId);
            // sedmlOriginalModel = sedml.getModelWithId(t.getModelReference());			// get model and simulation from subtask
            // sedmlSimulation = sedml.getSimulation(t.getSimulationReference());
            } else {
                throw new RuntimeException("Unexpected task " + selectedTask);
            }
            sedmlOriginalModelName = sedmlOriginalModel.getId();
            sedmlOriginalModelLanguage = sedmlOriginalModel.getLanguage();
            // at this point we assume that the sedml simulation, algorithm and kisaoID are all valid
            Algorithm algorithm = sedmlSimulation.getAlgorithm();
            kisaoID = algorithm.getKisaoID();
            // identify the vCell solvers that would match best the sedml solver kisao id
            // try to find a match in the ontology tree
            SolverDescription solverDescription = SolverUtilities.matchSolverWithKisaoId(kisaoID, exactMatchOnly);
            if (solverDescription != null) {
                System.out.println("Task (id='" + selectedTask.getId() + "') is compatible, solver match found in ontology: '" + kisaoID + "' matched to " + solverDescription);
            } else {
                // give it a try anyway with our deterministic default solver
                solverDescription = SolverDescription.CombinedSundials;
                System.err.println("Task (id='" + selectedTask.getId() + ")' is not compatible, no equivalent solver found in ontology for requested algorithm '" + kisaoID + "'; trying with deterministic default solver " + solverDescription);
            }
            // find out everything else we need about the application we're going to use,
            // some of the info will be needed when we parse the sbml file
            boolean bSpatial = false;
            Application appType = Application.NETWORK_DETERMINISTIC;
            Set<SolverDescription.SolverFeature> sfList = solverDescription.getSupportedFeatures();
            for (SolverDescription.SolverFeature sf : sfList) {
                switch(sf) {
                    case Feature_Rulebased:
                        appType = Application.RULE_BASED_STOCHASTIC;
                        break;
                    case Feature_Stochastic:
                        appType = Application.NETWORK_STOCHASTIC;
                        break;
                    case Feature_Deterministic:
                        appType = Application.NETWORK_DETERMINISTIC;
                        break;
                    case Feature_Spatial:
                        bSpatial = true;
                        break;
                    default:
                        break;
                }
            }
            // we make a biomodel for each task; if there are many simulations, probably
            // only one will match the selected task id, the others are parasites and must not be run
            BioModel bioModel = null;
            boolean justMade = false;
            String newMdl = resolver.getModelString(sedmlOriginalModel);
            String bioModelName = bioModelBaseName + "_" + sedml.getFileName() + "_" + sedmlOriginalModelName;
            // get it if we made it already
            for (VCDocument existingDoc : docs) {
                if (!docs.isEmpty()) {
                    if (existingDoc.getName().equals(bioModelName)) {
                        bioModel = (BioModel) existingDoc;
                        break;
                    }
                }
            }
            // make it if we didn't and mark it as fresh
            if (bioModel == null) {
                if (sedmlOriginalModelLanguage.contentEquals(SUPPORTED_LANGUAGE.VCELL_GENERIC.getURN())) {
                    // vcml
                    XMLSource vcmlSource = new XMLSource(newMdl);
                    bioModel = (BioModel) XmlHelper.XMLToBioModel(vcmlSource);
                    bioModel.setName(bioModelName);
                    docs.add(bioModel);
                    justMade = true;
                    try {
                        bioModel.getVCMetaData().createBioPaxObjects(bioModel);
                    } catch (Exception e) {
                        e.printStackTrace();
                    }
                } else {
                    // we assume it's sbml, if it's neither import will fail
                    // sbmlSource with all the changes applied
                    XMLSource sbmlSource = new XMLSource(newMdl);
                    bioModel = (BioModel) XmlHelper.importSBML(transLogger, sbmlSource, bSpatial);
                    bioModel.setName(bioModelName);
                    docs.add(bioModel);
                    justMade = true;
                }
            }
            if (sedmlOriginalModelLanguage.contentEquals(SUPPORTED_LANGUAGE.VCELL_GENERIC.getURN())) {
                // we basically ignore the sedml simulation altogether
                for (Simulation sim : bioModel.getSimulations()) {
                    if (sim.getName().equals(selectedTask.getName())) {
                        System.out.println(" --- selected task - name: " + selectedTask.getName() + ", id: " + selectedTask.getId());
                        sim.setImportedTaskID(selectedTask.getId());
                    }
                }
                continue;
            }
            // even if we just created the biomodel from the sbml file we have at least one application with initial conditions and stuff
            // see if there is a suitable application type for the sedml kisao
            // if not, we add one by doing a "copy as" to the right type
            SimulationContext[] existingSimulationContexts = bioModel.getSimulationContexts();
            SimulationContext matchingSimulationContext = null;
            for (SimulationContext simContext : existingSimulationContexts) {
                if (simContext.getApplicationType().equals(appType) && ((simContext.getGeometry().getDimension() > 0) == bSpatial)) {
                    matchingSimulationContext = simContext;
                    break;
                }
            }
            if (matchingSimulationContext == null) {
                if (justMade) {
                    matchingSimulationContext = SimulationContext.copySimulationContext(existingSimulationContexts[0], sedmlOriginalModelName, bSpatial, appType);
                    bioModel.removeSimulationContext(existingSimulationContexts[0]);
                } else {
                    matchingSimulationContext = SimulationContext.copySimulationContext(existingSimulationContexts[0], sedmlOriginalModelName + "_" + existingSimulationContexts.length, bSpatial, appType);
                }
                bioModel.addSimulationContext(matchingSimulationContext);
            }
            // making the new vCell simulation based on the sedml simulation
            matchingSimulationContext.refreshDependencies();
            MathMappingCallback callback = new MathMappingCallbackTaskAdapter(null);
            matchingSimulationContext.refreshMathDescription(callback, NetworkGenerationRequirements.ComputeFullStandardTimeout);
            Simulation newSimulation = new Simulation(matchingSimulationContext.getMathDescription());
            newSimulation.setSimulationOwner(matchingSimulationContext);
            if (selectedTask instanceof Task) {
                String newSimName = selectedTask.getId();
                if (SEDMLUtil.getName(selectedTask) != null) {
                    newSimName += "_" + SEDMLUtil.getName(selectedTask);
                }
                newSimulation.setName(newSimName);
                newSimulation.setImportedTaskID(selectedTask.getId());
            } else {
                newSimulation.setName(SEDMLUtil.getName(sedmlSimulation) + "_" + SEDMLUtil.getName(selectedTask));
            }
            // we identify the type of sedml simulation (uniform time course, etc)
            // and set the vCell simulation parameters accordingly
            SolverTaskDescription simTaskDesc = newSimulation.getSolverTaskDescription();
            if (solverDescription != null) {
                simTaskDesc.setSolverDescription(solverDescription);
            }
            TimeBounds timeBounds = new TimeBounds();
            TimeStep timeStep = new TimeStep();
            double outputTimeStep = 0.1;
            int outputNumberOfPoints = 1;
            if (sedmlSimulation instanceof UniformTimeCourse) {
                // we translate initial time to zero, we provide output for the duration of the simulation
                // because we can't select just an interval the way the SEDML simulation can
                double initialTime = ((UniformTimeCourse) sedmlSimulation).getInitialTime();
                double outputStartTime = ((UniformTimeCourse) sedmlSimulation).getOutputStartTime();
                double outputEndTime = ((UniformTimeCourse) sedmlSimulation).getOutputEndTime();
                outputNumberOfPoints = ((UniformTimeCourse) sedmlSimulation).getNumberOfPoints();
                outputTimeStep = (outputEndTime - outputStartTime) / outputNumberOfPoints;
                timeBounds = new TimeBounds(0, outputEndTime - initialTime);
                ErrorTolerance errorTolerance = new ErrorTolerance();
                // we look for explicit algorithm parameters
                List<AlgorithmParameter> sedmlAlgorithmParameters = algorithm.getListOfAlgorithmParameters();
                for (AlgorithmParameter sedmlAlgorithmParameter : sedmlAlgorithmParameters) {
                    String apKisaoID = sedmlAlgorithmParameter.getKisaoID();
                    String apValue = sedmlAlgorithmParameter.getValue();
                    if (apKisaoID == null || apKisaoID.isEmpty()) {
                        System.err.println("Undefined KisaoID algorithm parameter for algorithm '" + kisaoID + "'");
                    }
                    // TODO: use the proper ontology for the algorithm parameters kisao id
                    if (apKisaoID.contentEquals(ErrorTolerance.ErrorToleranceDescription.Absolute.getKisao())) {
                        double value = Double.parseDouble(apValue);
                        errorTolerance.setAbsoluteErrorTolerance(value);
                    } else if (apKisaoID.contentEquals(ErrorTolerance.ErrorToleranceDescription.Relative.getKisao())) {
                        double value = Double.parseDouble(apValue);
                        errorTolerance.setRelativeErrorTolerance(value);
                    } else if (apKisaoID.contentEquals(TimeStep.TimeStepDescription.Default.getKisao())) {
                        double value = Double.parseDouble(apValue);
                        timeStep.setDefaultTimeStep(value);
                    } else if (apKisaoID.contentEquals(TimeStep.TimeStepDescription.Maximum.getKisao())) {
                        double value = Double.parseDouble(apValue);
                        timeStep.setMaximumTimeStep(value);
                    } else if (apKisaoID.contentEquals(TimeStep.TimeStepDescription.Minimum.getKisao())) {
                        double value = Double.parseDouble(apValue);
                        timeStep.setMinimumTimeStep(value);
                    } else if (apKisaoID.contentEquals(AlgorithmParameterDescription.Seed.getKisao())) {
                        // custom seed
                        if (simTaskDesc.getSimulation().getMathDescription().isNonSpatialStoch()) {
                            NonspatialStochSimOptions nssso = simTaskDesc.getStochOpt();
                            int value = Integer.parseInt(apValue);
                            nssso.setCustomSeed(value);
                        } else {
                            System.err.println("Algorithm parameter '" + AlgorithmParameterDescription.Seed.getDescription() + "' is only supported for nonspatial stochastic simulations");
                        }
                    // some arguments used only for non-spatial hybrid solvers
                    } else if (apKisaoID.contentEquals(AlgorithmParameterDescription.Epsilon.getKisao())) {
                        NonspatialStochHybridOptions nssho = simTaskDesc.getStochHybridOpt();
                        nssho.setEpsilon(Double.parseDouble(apValue));
                    } else if (apKisaoID.contentEquals(AlgorithmParameterDescription.Lambda.getKisao())) {
                        NonspatialStochHybridOptions nssho = simTaskDesc.getStochHybridOpt();
                        nssho.setLambda(Double.parseDouble(apValue));
                    } else if (apKisaoID.contentEquals(AlgorithmParameterDescription.MSRTolerance.getKisao())) {
                        NonspatialStochHybridOptions nssho = simTaskDesc.getStochHybridOpt();
                        nssho.setMSRTolerance(Double.parseDouble(apValue));
                    } else if (apKisaoID.contentEquals(AlgorithmParameterDescription.SDETolerance.getKisao())) {
                        NonspatialStochHybridOptions nssho = simTaskDesc.getStochHybridOpt();
                        nssho.setSDETolerance(Double.parseDouble(apValue));
                    } else {
                        System.err.println("Algorithm parameter with kisao id '" + apKisaoID + "' not supported at this time, skipping.");
                    }
                }
                simTaskDesc.setErrorTolerance(errorTolerance);
            } else if (sedmlSimulation instanceof OneStep) {
                // for anything other than UniformTimeCourse we just ignore
                System.err.println("OneStep Simulation not supported");
                continue;
            } else if (sedmlSimulation instanceof SteadyState) {
                System.err.println("SteadyState Simulation not supported");
                continue;
            }
            OutputTimeSpec outputTimeSpec = new UniformOutputTimeSpec(outputTimeStep);
            simTaskDesc.setTimeBounds(timeBounds);
            simTaskDesc.setTimeStep(timeStep);
            if (simTaskDesc.getSolverDescription().supports(outputTimeSpec)) {
                simTaskDesc.setOutputTimeSpec(outputTimeSpec);
            } else {
                simTaskDesc.setOutputTimeSpec(new DefaultOutputTimeSpec(1, Integer.max(DefaultOutputTimeSpec.DEFAULT_KEEP_AT_MOST, outputNumberOfPoints)));
            }
            newSimulation.setSolverTaskDescription(simTaskDesc);
            newSimulation.setDescription(SEDMLUtil.getName(selectedTask));
            bioModel.addSimulation(newSimulation);
            newSimulation.refreshDependencies();
        }
        return docs;
    } catch (Exception e) {
        e.printStackTrace();
        throw new RuntimeException("Unable to initialize bioModel for the given selection\n" + e.getMessage());
    }
}